Quantitative and qualitative assessment of left ventricular volume with                ECG-gated multislice spiral CT: value of different image reconstruction algorithms in                comparison to MRI

Mahnken, Andreas H.; Spuentrup, Elmar; Niethammer, M.; Buecker, Arno; Boese, Jan; Wildberger, JE; Flohr, T.; Sinha, Anil‐Martin; Krombach, Gabriele A.; Günther, Rolf W.

doi:10.1080/02841850312331287799

Cited by 84 publications

(14 citation statements)

References 26 publications

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“…A lesser amount of information on regional wall motion evaluation with CT has been reported [9, 28,31,32,33,34,35,36,37]. In our study, areas of impaired motion identified by CT showed good agreements in comparison with LVG and CMR in segmental analysis.…”

Section: Discussionsupporting

confidence: 63%

“…The feasibility of CT for the evaluation of LV function has been investigated [9, 10,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38]. LV functional analysis by CT has its inherited disadvantage including a higher radiation dose (by avoiding dose modulation protocols) and a longer postprocessing time.…”

Section: Discussionmentioning

confidence: 99%

“…Lately, advances of 64-slice CT provide great improvement in coronary imaging [6,7,8], and the segmental reconstruction algorithm that uses data from several heartbeats further enhances temporal resolution as heart rates increase [9,10,11,12]. So far, only a limited number of functional studies were published comparing 64-slice CT with CMR or LVG.…”

Section: Introductionmentioning

confidence: 99%

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Left Ventricular Functional Analysis Using 64-Slice Multidetector Row Computed Tomography: Comparison with Left Ventriculography and Cardiovascular Magnetic Resonance

Tadamura²,

Kanao³

et al. 2007

Cardiology

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Objective: The progress in computed tomography (CT) has improved temporal resolution and shortened the acquisition time. We compared cardiac function using 64-slice CT with left ventriculography (LVG) and cardiovascular magnetic resonance (CMR). Methods: A head-to-head comparison between CT, LVG and CMR was performed in 41 patients. In global LV function, CMR served as the reference. Regional wall motion was compared in a 5-point scoring system. Results: CT had excellent intra- and interobserver reproducibility. Ejection fraction, end-diastolic and end-systolic volumes by CT were closely correlated with CMR (r = 0.95, 0.96 and 0.98, respectively), while LVG underestimated LV volumes (p < 0.01). The standard deviation of ejection fraction difference between CT and CMR was significantly lower than that between LVG and CMR (p = 0.0015). In regional function, there were good agreements of 94.8% (ĸ = 0.82) between CT and LVG and 94.5% (ĸ = 0.84) between CT and CMR. The intermethod agreements in mild hypokinesis using CT tended to be lower. Conclusion: An excellent correlation was observed between CT and CMR in the LV function over a wide range of heart rates. However, even though 64-slice CT tended to be less sensitive in detecting mild hypokinesis, it still showed excellent concordance in advanced regional abnormalities.

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Section: Discussionsupporting

confidence: 63%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Left Ventricular Functional Analysis Using 64-Slice Multidetector Row Computed Tomography: Comparison with Left Ventriculography and Cardiovascular Magnetic Resonance

Tadamura²,

Kanao³

et al. 2007

Cardiology

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“…Also, analysis of multiplanar reformations of retrospectively ECG-gated MDCT coronary angiography data permits the assessment of left ventricular function and volumes [18]. However, the major drawback of MDCT measurements is the overestimation of EDV and ESV compared with MRI as the standard of reference.…”

Section: Discussionmentioning

confidence: 99%

Comparison of Gated Blood Pool SPECT and Multi-Detector Row Computed Tomography for Measurements of Left Ventricular Volumes and Ejection Fraction in Patients with Atypical Chest Pain: Validation with Radionuclide Ventriculography

Kim

Choo

Lee³

et al. 2006

Cardiology

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Gated blood pool SPECT (GBPS) is an alternative to planar radionuclide ventriculography (PRNV) and offers potential advantages. The aim of this study was to compare GBPS, multi-row detector spiral computed tomography (MDCT), and PRNV for the determination of left ventricular ejection fraction (LVEF) and left ventricular volumes (LV) in subjects with atypical chest pain. Method: Twenty-three consecutive patients (14 men, 9 women; mean age 56.2 ± 9.5 years) referred for MDCT for evaluation of atypical chest pain. All patients underwent PRNV, GBPS, and MDCT at the same day. Results: The mean LVEFs calculated with PRNA (57.3 ± 8.6%), GBPS (55.2 ± 6.6%), and MDCT (56 ± 9.1%) were not statistically different (F value 0.3374, p = 0.715). Comparison of LVEFs from GBPS and MDCT yielded correlation coefficients of 0.5238 (p = 0.0178, 95% CI = 0.1057–0.7845). The correlation of LVEFs between GBPS and PRNV showed a correlation coefficient of 0.8073 (p < 0.0001, 95% CI = 0.5676–0.9209) and 0.6190 (p = 0.0036, 95% CI = 0.2431–0.8333) between MDCT and PRNV. The mean LV end-diastolic volume (EDV) calculated with GBPS (82.7 ± 17.5 ml) was significantly lower than MDCT (106.8 ± 18.5 ml) (p = 0.0001). The mean LV end-systolic volume (ESV) calculated with GBPS (37.2 ± 9.6 ml) was also significantly lower than MDCT (48.1 ± 15.8 ml) (p = 0.012). Comparison of EDV from GBPS and MDCT yielded a correlation coefficient of 0.5220 (p = 0.0182, 95% CI = 0.1033–0.7835). The correlation of ESV between GBPS and MDCT showed a correlation coefficient of 0.6642 (p = 0.0014, 95% CI = 0.3140–0.8553). Conclusion: In conclusion, the LVEF, EDV, and ESV calculated by GBPS correlated significantly with those of obtained with 16-MDCT. In addition, there were no statistical differences of LVEF calculated from PRNV, GBPS, and MDCT. However, with regard to LV, EDV and ESV from GBPS revealed statistically significantly lower than those of MDCT. Also, these results should be addressed whether similar results could also be found in patients with cardiac diseases by the consequent larger population-based study.

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“…Several studies have shown the ability of electronbeam computed tomography and multidetector spiral computed tomography (MDCT) to assess left ventricular function and mass by multiplanar reformation algorithms using short-axis images (9,13,18,19). Due to retrospective gating used for cardiac MDCT, all data for the analysis of left ventricular parameters can be calculated from a standard MDCT coronary angiography data set without any additional radiation exposure.…”

mentioning

confidence: 99%

Assessment of left ventricular function and mass in patients undergoing computed tomography (CT) coronary angiography using 64-detector-row CT: comparison to magnetic resonance imaging

Schlosser¹,

Mohrs²,

Magedanz³

et al. 2007

Acta Radiol

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Quantitative and qualitative assessment of left ventricular volume with ECG-gated multislice spiral CT: value of different image reconstruction algorithms in comparison to MRI

Abstract: Multisegmental image reconstruction improves the quantitative assessment of left ventricular function when compared to standard image reconstruction. Multisegmental image reconstruction allows qualitative wall motion analysis.

Cited by 84 publications

References 26 publications

Left Ventricular Functional Analysis Using 64-Slice Multidetector Row Computed Tomography: Comparison with Left Ventriculography and Cardiovascular Magnetic Resonance

Left Ventricular Functional Analysis Using 64-Slice Multidetector Row Computed Tomography: Comparison with Left Ventriculography and Cardiovascular Magnetic Resonance

Comparison of Gated Blood Pool SPECT and Multi-Detector Row Computed Tomography for Measurements of Left Ventricular Volumes and Ejection Fraction in Patients with Atypical Chest Pain: Validation with Radionuclide Ventriculography

Assessment of left ventricular function and mass in patients undergoing computed tomography (CT) coronary angiography using 64-detector-row CT: comparison to magnetic resonance imaging

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