Quantitative<i>In Silico</i>Analysis of Retention of Phenylthiohydantoin-Amino Acids in Reversed-Phase Ion-Pair Liquid Chromatography

Hanai, Toshihiko

doi:10.1093/chromsci/bmv194

Cited by 6 publications

(1 citation statement)

References 2 publications

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“…Rumus senyawa dari amonia adalah NH 3 (aq). Nama dari amonium hidroksida memperlihatkan suatu alkali dengan komposisi [NH4 + ][OH − ], faktanya NH4OH sangat sulit untuk dipisahkan, karena ion dari NH4OH tidak FINISH terdiri dari bagian yang substansial dari seluruh amonia kecuali di dalam larutan yang sangat encer (109)(110)(111)(112)(113)(114)(115)(116) .…”

Section: Pembahasan A) Sifat Amonium Hidroksida (Nh4oh)unclassified

Interaksi Molekuler Amonium Hidroksida

Lubis¹,

Zainul²

2018

Preprint

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Amonium hidroksida adalah larutan amonia didalam air dengan rumus NH4OH. Amonium hidroksida merupakan senyawa yang tidak berwarna dan memiliki bau yang sangat tajam. Penelitian ini bertujuan untuk menganalisis interaksi molekuler dan kinetik dari amonium hidroksida. Metode yang digunakan adalah pemodelan dengan ChemOffice 15.0. Untuk mengetahui konduktivitas, mobilitas, viskositas, kecepatan hanyut dilakukan dengan menggunakan rumus dan data dari hasil riview jurnal penelitian yang berkaitan dengan amonium hidroksida seperti tahapan pada fishbond. Amonium hidroksida mempunyai termokimia dalam fase liquit dengan ∆𝐻,∆𝐺,𝑆°, 𝑑𝑎𝑛 𝐶𝑝 yang masing-masing mempunyai nilai -361.2 kj/mol, -254.0 kj/mol, 165.6 J/molK dan 154.9 J/molK. Mobilitas ion NH4 dan OH- adalah 3.5 dan 1. Amonium hidroksida juga mempunyai energi kinetik yang hasilnya dapat diketahui dengan menggunakan chemoffice 15.0 yaitu sebesar 0,43

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Section: Pembahasan A) Sifat Amonium Hidroksida (Nh4oh)unclassified

Interaksi Molekuler Amonium Hidroksida

Lubis¹,

Zainul²

2018

Preprint

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Sensor Array Based Determination of Edman Degradated Amino Acids Using Poly(p‐phenyleneethynylene)s

Zhang

Wang

Seehafer

et al. 2020

Chemistry A European J

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A cross‐reactive optical sensor array based on poly( p ‐phenyleneethynylene)s (PPEs) determines Edman degraded amino acids. We report a sensor array composed of three anionic PPEs P1–P3 , and their electrostatic complexes with metal ions (Fe 2+ , Cu 2+ , Co 2+ ). We recorded distinct fluorescence intensity response patterns as “fingerprints” of this chemical tongue toward standard phenylthiohydantoin (PTH) amino acids—degradation products of the Edman process. These “fingerprints” were converted into canonical scores by linear discrimination analysis (LDA), which differentiates all of the PTH‐amino acids. This array discriminates PTH‐amino acid residues degraded from an oligopeptide through Edman sequencing. This approach is complementary to chromatography approaches which rely on mass spectrometry; our array offers the advantage of simplicity.

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Spectrophotometric Determination of Some Phenolic Compounds by Formation of Copper(II) Complexes

Abd-Alrassol

Jasim

2019

IOP Conf. Ser.: Mater. Sci. Eng.

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Simple and sensitive spectrophotometric method is described for the determination of phenolic compounds in both in pure form and in pharmaceutical preparations. The method is based on the formation of a new ligand from the reaction between 4-aminoantipyrine with phenolic compounds and then reacts with copper (II) to give a colored complex at room temperature. The maximum absorbance of the prepared complexes were measured at 450,500 and 480 nm for pyridoxine, resorcinol and phloroglucinol complexes respectively. Beer’s law was obeyed in the concentration range of 1.5-20, 2.530 and 2.0-25 μg/ml-1, the molar absorptivity values are 2.4778 x 104,1.6740x104 and 1.7001 x 104 L mol−1cm−1, the Sandal sensitivity values are 0.0501x10−3,0.1740x10−3and 0.1228x10−3μg cm−2 for Pyridoxine, resorcinol and phloroglucinol complexes respectively. The correlation coefficients were 0.9999, 0.9998 and 0.9999, the limits of detection(LOD) were 0.47793, 0.15125 and 0.01434μg ml−1, the limits of quantification were (LOQ) 1.4482, 0.45833 and 0.04347 for pyridoxine, resorcinol and phloroglucinol complexes respectively. The stoichiometry of the complexes formed (1:2) was determined by Job’s continuous variations method and molar ratio method. Furthermore the stability constant (K) and Gibbs free energy ΔG) for the complexes were also calculated. The proposed methods were applied successfully for the determination of phenolic compounds in commercial tablets.

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QuantitativeIn SilicoAnalysis of Retention of Phenylthiohydantoin-Amino Acids in Reversed-Phase Ion-Pair Liquid Chromatography

Cited by 6 publications

References 2 publications

Interaksi Molekuler Amonium Hidroksida

Interaksi Molekuler Amonium Hidroksida

Sensor Array Based Determination of Edman Degradated Amino Acids Using Poly(p‐phenyleneethynylene)s

Spectrophotometric Determination of Some Phenolic Compounds by Formation of Copper(II) Complexes

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