Quantitative elastography of renal transplants using supersonic shear imaging: a pilot study

Abstract

• Supersonic shear imaging elastography can measure cortical stiffness in renal transplants • The level of cortical stiffness is correlated with the global degree of tissue lesions • The global histological deterioration of transplanted kidneys can be quantified using elastography.

Kidney Ultrasound Elastography: Review

“…We excluded these articles. The rest amount of related articles were 13 4,5,[8][9][10][11]13,14,25,[71][72][73][74] . But, pubmed search missed some articles 6,7,12,35,75 , that was mentioned in this paper (Table 1).…”

“…Some of them are functional, systemic and diffuse, while some are local and massy, and also vascular, congenital, hereditary and acquired 2,3 . Among all the disorders, chronic kidney disease (CKD) and transplanted kidneys are the subject of elastography in a majority of studies [4][5][6][7][8][9][10][11][12][13][14] . CKD is an important and costly health problem because of not only the increasing incidence and prevalence but also resulting in endstage renal failure.…”

Renal Allograft Fibrosis: Biology and Therapeutic Targets

“…In renal allografts, the two main modalities to assess fibrosis are ultrasound and magnetic resonance imaging (MRI). Ultrasound-based measurement of tissue elasticity (elastography), an approach relatively well established in the assessment of liver fibrosis, has been suggested to correlate with fibrosis in kidney allografts (420)(421)(422)(423)(424), but others have found no such correlation (425). MRI-based elastography is an alternative approach, but the first findings in kidney allografts with fibrosis were disappointing (426).…”

Стеноз Ниркової Артерії Трансплантованої Нирки

“…Grenier с соавт. ука-зывают, что у здоровых добровольцев жесткость кортикального слоя была 15,4 ± 2,5 кПа, а медул-лярного -10, 8 Наши данные в обоих наблюдениях для нижне-го полюса с постоянно сохраненной перфузией де-монстрируют сходные результаты. Нарушение кро-вотока в верхнем и срединном сегментах привело к существенному снижению жесткости паренхимы.…”