Quantitative EEG in elderly depressives

Roemer, Richard A.; Shagass, Charles; Dubin, William R.; Jaffe, Richard L.; Siegal, Lynn

doi:10.1007/bf01135566

Cited by 73 publications

(33 citation statements)

References 15 publications

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“…In MDD a consistent finding is an elevated absolute [66,67,68,69,70] or relative alpha power [71,72] at mainly parietal and frontal [68,73] or occipital sites [74]. The reason that some studies did not find alpha power differences between patients and HCs [75,76] or found decreased (relative) alpha activity in comparison to other patient groups [77] might be related to differences of recording periods, where shorter recording periods prevent the differences described above [38,39] in vigilance regulation to occur (e.g.…”

Section: Biomarkersmentioning

confidence: 63%

“…Several studies have reported elevated slow-wave activity in MDD [69,98,99,100,101], with the focus of this elevated theta activity localized to frontal areas and often to the anterior cingulate cortex (ACC) [68,101,102], though decreased ACC activity in MDD has also been reported [103] and some studies found no differences between MDD and controls [104,105]. …”

Section: Biomarkersmentioning

confidence: 99%

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Personalized Medicine: Review and Perspectives of Promising Baseline EEG Biomarkers in Major Depressive Disorder and Attention Deficit Hyperactivity Disorder

2015

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Personalized medicine in psychiatry is in need of biomarkers that resemble central nervous system function at the level of neuronal activity. Electroencephalography (EEG) during sleep or resting-state conditions and event-related potentials (ERPs) have not only been used to discriminate patients from healthy subjects, but also for the prediction of treatment outcome in various psychiatric diseases, yielding information about tailored therapy approaches for an individual. This review focuses on baseline EEG markers for two psychiatric conditions, namely major depressive disorder and attention deficit hyperactivity disorder. It covers potential biomarkers from EEG sleep research and vigilance regulation, paroxysmal EEG patterns and epileptiform discharges, quantitative EEG features within the EEG main frequency bands, connectivity markers and ERP components that might help to identify favourable treatment outcome. Further, the various markers are discussed in the context of their potential clinical value and as research domain criteria, before giving an outline for future studies that are needed to pave the way to an electrophysiological biomarker-based personalized medicine.

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Section: Biomarkersmentioning

confidence: 63%

Section: Biomarkersmentioning

confidence: 99%

Personalized Medicine: Review and Perspectives of Promising Baseline EEG Biomarkers in Major Depressive Disorder and Attention Deficit Hyperactivity Disorder

2015

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“…The inverse relation between alpha power in EEG and cortical activation (Cook, O'Hara, Uijtdehaage, Mandelkern, & Leuchter, 1998) can reflect cortical hypoactivation in these areas of the brain. Several studies reported an increase in slow-wave activity over the right (Kwon, Youn, & Jung, 1996;Volf & Passynkova, 2002) and left (Roemer, Shagass, Dubin, Jaffe, & Siegal, 1992) hemispheres.…”

Section: Introductionmentioning

confidence: 99%

Infra-Low Frequency Neurofeedback in Depression: Three case studies

Grin-Yatsenko

Othmer²,

Пономарев

et al. 2018

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Electroencephalographic (EEG) findings on depressive patients indicate theta and alpha activity higher than in normal controls. Extensive literature reports on the effectiveness of neurofeedback techniques in the treatment of cognitive and behavioral disorders by training the patients to modulate their brain activities, as reflected in their electroencephalogram. Three unmedicated, depressed individuals participated in this study of infra-low frequency neurofeedback (ILF NF) training. Along with the pre-and posttreatment Depression Rating Scales assessment, quantitative EEGs (qEEG) were recorded in eyes-open and eyes-closed resting states and during the visual cued Go/NoGo task before and after 20 sessions of training. Along with remission of the clinical symptoms of depression, significant decrease of theta power over frontal and central areas was observed in all three patients under all test conditions. These qEEG dynamics might be a correlate of ILF NF-related recovery of the appropriate level of frontal cortical activation.Keywords: neurophysiology; neurofeedback; depression; qEEG; infra-low frequency

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“…Aplicase o EEGq no diagnóstico e avaliação evolutiva das fases inicial ou intermediária das demências, quando os dados clínicos não tenham sido conclusivos (classe de evidência I I ) 5 4 . O aumento relativo da atividade lenta sugere org anicidade, ao contrário de depressão e ansiedade (classe de evidência III) [59][60][61][62][63][64][65][66][67][68][69] .…”

Section: Eletrencefalografia E Potenciais Evocadosunclassified

Diagnóstico de doença de Alzheimer no Brasil: critérios diagnósticos e exames complementares. Recomendações do Departamento Científico de Neurologia Cognitiva e do Envelhecimento da Academia Brasileira de Neurologia

Nitrini¹,

Caramelli²,

Bottino³

et al. 2005

Arq. Neuro-Psiquiatr.

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RESUMO -Este consenso teve o objetivo de recomendar condutas baseadas em evidências para o diagnóstico clínico de doença de Alzheimer (DA) em nosso meio. Foram avaliados sistematicamente consensos elaborados em outros países e artigos sobre o diagnóstico de DA no Brasil disponíveis no PUBMED ou LILACS. Concluiuse que o diagnóstico de demência deve basear-se nos critérios do Manual de Diagnóstico e Estatística da Associação Psiquiátrica Americana (DSM) e o de DA, nos de McKhann et al. (NINCDS-ADRDA). Os exames c o m p l e m e n t a res recomendados são: hemograma completo, concentrações séricas de uréia, cre a t i n i n a , t i roxina livre, hormônio tíreo-estimulante, albumina, enzimas hepáticas, vitamina B12 e cálcio, re a ç õ e s sorológicas para sífilis e, em pacientes com idade inferior a 60 anos, sorologia para HIV. Exame do líquido cefalorraqueano está indicado em situações particulares. Tomografia computadorizada (ou preferentemente ressonância magnética, quando disponível) é exame obrigatório e tem a finalidade principal de excluir outras doenças. Cintilografia de perfusão (SPECT) e EEG são métodos opcionais. PALAVRAS-CHAVE: consenso, diretrizes, normas, diagnóstico, doença de Alzheimer, demência, Brasil. Guidelines from other countries and papers on the diagnosis of AD in Brazil were systematically evaluated in a thorough re s e a rch of PUBMED and LILACS databases. The panel concluded that dementia diagnosis should be based on the DSM criteria and AD diagnosis, on the McKhann et al. criteria (NINCDS-ADRDA). The recommended auxiliary tests are: blood cell count, blood urea nitrogen, serum levels of creatinine, fre e -tyroxine,thyroid-stimulant hormone, albumin, hepatic enzymes, vitamin B12 and calcium, serological tests for syphilis and, for those aged less than 60 years, s e rological tests for HIV. Cere b rospinal fluid examination is recommended in special situations. Computed tomography (or pre f e rentially magnetic resonance imaging, when available) is mandatory and has the main objective of excluding other diseases. SPECT and EEG are optional diagnostic methods. Diagnosis of Alzheimer's disease in

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Quantitative EEG in elderly depressives

Cited by 73 publications

References 15 publications

Personalized Medicine: Review and Perspectives of Promising Baseline EEG Biomarkers in Major Depressive Disorder and Attention Deficit Hyperactivity Disorder

Personalized Medicine: Review and Perspectives of Promising Baseline EEG Biomarkers in Major Depressive Disorder and Attention Deficit Hyperactivity Disorder

Infra-Low Frequency Neurofeedback in Depression: Three case studies

Diagnóstico de doença de Alzheimer no Brasil: critérios diagnósticos e exames complementares. Recomendações do Departamento Científico de Neurologia Cognitiva e do Envelhecimento da Academia Brasileira de Neurologia

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