Quantitative comparison of tympanic membrane displacements using two optical methods to recover the optical phase

Santiago-Lona, Cynthia V.; Hernández-Montes, María del Socorro; Mendoza-Santoyo, Fernando; Esquivel-Tejeda, Jesús

doi:10.1080/09500340.2017.1390173

Cited by 3 publications

(2 citation statements)

References 29 publications

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“…Over the past decade, various non-invasive optical methods, for example, holographic interferometric methods, were developed to quantify TM dynamics such as excitation-induced displacements, and physical characteristics such as shape and thickness [11,[16][17][18][19][20][21][22][23][24][25][26]. However, a study on the live subject remains challenging due to the natural noise, such as motions due to respiration, heartbeat, muscle tremor, etc.…”

Section: Introductionmentioning

confidence: 99%

High-Speed Holographic Shape and Full-Field Displacement Measurements of the Tympanic Membrane in Normal and Experimentally Simulated Pathological Ears

et al. 2019

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To improve the understanding of the middle-ear hearing mechanism and assist in the diagnosis of middle-ear diseases, we are developing a high-speed digital holographic (HDH) system to measure the shape and acoustically-induced transient displacements of the tympanic membrane (TM). In this paper, we performed measurements on cadaveric human ears with simulated common middle-ear pathologies. The frequency response function (FRF) of the normalized displacement by the stimulus (sound pressure) at each measured pixel point of the entire TM surface was calculated and the complex modal indicator function (CMIF) of the middle-ear system based on FRFs of the entire TM surface motions was used to differentiate different middle-ear pathologies. We also observed changes in the TM shape and the surface motion pattern before and after various middle-ear manipulations. The observations of distinguishable TM shapes and motion patterns in both time and frequency domains between normal and experimentally simulated pathological ears support the development of a quantitative clinical holography-based apparatus for diagnosing middle-ear pathologies.

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Section: Introductionmentioning

confidence: 99%

High-Speed Holographic Shape and Full-Field Displacement Measurements of the Tympanic Membrane in Normal and Experimentally Simulated Pathological Ears

et al. 2019

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“…Over the past decade, various holographic methodologies were developed to quantify TM functional parameters such as excitation induced displacements, shape, and thickness. 11,[18][19][20][21][22][23][24][25][26][27][28] One of the main challenges in holographic measurements of TM acoustically induced nanometer-scale motions is the high sensitivity to physiological motions (micrometer to submillimeter) in live ears (motions due to respiration, heartbeat, muscle tremor, etc.). To solve this problem, high-speed digital holographic (HDH) methods were developed to measure the TM motions produced by brief acoustic transients (click response with duration of <5 ms).…”

Section: Introductionmentioning

confidence: 99%

Combined high-speed holographic shape and full-field displacement measurements of tympanic membrane

et al. 2018

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The conical shape of the tympanic membrane (TM or eardrum) plays an important role in its function, such that variations in shape alter the acoustically induced motions of the TM. We present a method that precisely determines both shape and acoustically induced transient response of the entire TM using the same optics and maintaining the same coordinate system, where the TM transient displacements due to a broadband acoustic click excitation (50-μs impulse) and the shape are consecutively measured within <200 ms. Interferograms gathered with continuous high-speed (>2 kHz) optical phase sampling during a single 100-ms wavelength tuning ramp allow precise and rapid reconstructions of the TM shape at varied resolutions (50 to 200 μm). This rapid acquisition of full-field displacements and shape is immune to slow disturbances introduced by breathing or heartbeat of live subjects. Knowledge of TM shape and displacements enables the estimation of surface normal displacements regardless of the orientation of the TM within the measurement system. The proposed method helps better define TM mechanics and provides TM structure and function information useful for the diagnosis of ear disease.

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Tympanic membrane displacement and thickness data correlation using digital holographic interferometry and confocal laser scanning microscopy

et al. 2019

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Quantitative comparison of tympanic membrane displacements using two optical methods to recover the optical phase

Cited by 3 publications

References 29 publications

High-Speed Holographic Shape and Full-Field Displacement Measurements of the Tympanic Membrane in Normal and Experimentally Simulated Pathological Ears

High-Speed Holographic Shape and Full-Field Displacement Measurements of the Tympanic Membrane in Normal and Experimentally Simulated Pathological Ears

Combined high-speed holographic shape and full-field displacement measurements of tympanic membrane

Tympanic membrane displacement and thickness data correlation using digital holographic interferometry and confocal laser scanning microscopy

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