Quantitative brain-derived neurotrophic factor lateral flow assay for point-of-care detection of glaucoma

Wu, Yue; Hu, Yubing; Jiang, Nan; Anantharanjit, Rajeevan; Yetisen, Ali K.; Cordeiro, M. Francesca

doi:10.1039/d2lc00431c

Cited by 7 publications

(5 citation statements)

References 55 publications

(124 reference statements)

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“…Three-dimensional printing technology has enabled the development of cutting-edge tools for researching, diagnosing, and monitoring glaucoma. A pioneering team developed a rapid, portable, and cost-effective glaucoma-detecting device consisting of a 3D-printed readout box and a smartphone camera, suitable for point-of-care settings, promoting the early identification of glaucoma [ 96 ]. Furthermore, 3D printing’s high resolution and customization capabilities with various ink materials can be applied to smart contact lens fabrication.…”

Section: Applications In Glaucoma Therapeuticsmentioning

confidence: 99%

Towards Precision Ophthalmology: The Role of 3D Printing and Bioprinting in Oculoplastic Surgery, Retinal, Corneal, and Glaucoma Treatment

Wu,

Tabari,

Mazerolle

et al. 2024

Biomimetics

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In the forefront of ophthalmic innovation, biomimetic 3D printing and bioprinting technologies are redefining patient-specific therapeutic strategies. This critical review systematically evaluates their application spectrum, spanning oculoplastic reconstruction, retinal tissue engineering, corneal transplantation, and targeted glaucoma treatments. It highlights the intricacies of these technologies, including the fundamental principles, advanced materials, and bioinks that facilitate the replication of ocular tissue architecture. The synthesis of primary studies from 2014 to 2023 provides a rigorous analysis of their evolution and current clinical implications. This review is unique in its holistic approach, juxtaposing the scientific underpinnings with clinical realities, thereby delineating the advantages over conventional modalities, and identifying translational barriers. It elucidates persistent knowledge deficits and outlines future research directions. It ultimately accentuates the imperative for multidisciplinary collaboration to enhance the clinical integration of these biotechnologies, culminating in a paradigm shift towards individualized ophthalmic care.

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Section: Applications In Glaucoma Therapeuticsmentioning

confidence: 99%

Towards Precision Ophthalmology: The Role of 3D Printing and Bioprinting in Oculoplastic Surgery, Retinal, Corneal, and Glaucoma Treatment

Wu,

Tabari,

Mazerolle

et al. 2024

Biomimetics

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“…Similar to sweat, the physicochemical properties and enrichment of tears can be detected non‐invasively with colorimetric biosensors to determine the health status of the living body 95–97 . Contact lenses combined with colorimetric sensors have been widely used for in situ monitoring of tears.…”

Section: Colorimetric and Fluorescence Biosensingmentioning

confidence: 99%

“…Similar to sweat, the physicochemical properties and enrichment of tears can be detected non-invasively with colorimetric biosensors to determine the health status of the living body. [95][96][97] Contact lenses combined with colorimetric sensors have been widely used for in situ monitoring of tears. Riaz et al employed Anthocyanin pigments to functionalize the polymeric matrices of contact lenses to continuously monitor the ocular pH values.…”

Section: Tears Detectionmentioning

confidence: 99%

Optical biosensing systems for a biological living body

Yan

Guo

Wang

et al. 2023

VIEW

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With the development of technology, biosensors are increasingly used in the biomedical field. Due to the high sensitivity of optical signals, good stability, high signal‐to‐noise ratio, and different spectral characteristics of different analytes, optical biosensors can achieve direct and real‐time detection of analytes with high specificity compared with traditional analytical techniques. In view of the rapid development of optical biosensors for in vivo applications and their promising future, we have attempted to summarize the working principles and recent advances in application in humans, with the aim of helping readers to gain an in‐depth and detailed understanding of optical biosensors developed in recent years for applications in the biological living body. In this review, we focus on some of the current widely used and promising optical biosensors, including colorimetric biosensors, fluorescence biosensors, and surface‐enhanced‐Raman‐scattering‐based biosensors. The working principles for each type of optical biosensor are concisely described and the application of the biosensor in the living body is summarized by category. We conclude by looking at the prospects of in vivo applications of optical biosensors.

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“…The detection limit was 14.12 pg mL −1 . 63 Park et al successfully measured the uric acid content (25-150 μM) in tears using surface-enhanced Raman scattering LFA strips, revealing a strong linear correlation between human tears and blood uric acid levels in the diagnosis of gouty arthritis. 64 2.5 Immobilized bioreceptors 2.5.1 Antibody.…”

Section: Sample Typementioning

confidence: 99%

Lateral flow assay of pathogenic viruses and bacteria in healthcare

Nan¹,

Yao²,

Li³

et al. 2023

Analyst

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Quantitative brain-derived neurotrophic factor lateral flow assay for point-of-care detection of glaucoma

Abstract: Glaucoma, a ruinous group of eye diseases with progressive degeneration of optic nerve and vision loss, is the most leading cause of irreversible blindness. Accurate and timely diagnosis of glaucoma...

Cited by 7 publications

References 55 publications

Towards Precision Ophthalmology: The Role of 3D Printing and Bioprinting in Oculoplastic Surgery, Retinal, Corneal, and Glaucoma Treatment

Towards Precision Ophthalmology: The Role of 3D Printing and Bioprinting in Oculoplastic Surgery, Retinal, Corneal, and Glaucoma Treatment

Optical biosensing systems for a biological living body

Lateral flow assay of pathogenic viruses and bacteria in healthcare

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