Quantitative assessment of endomyocardial biopsy in arrhythmogenic right ventricular cardiomyopathy/dysplasia: an in vitro validation of diagnostic criteria

Basso, Cristina; Ronco, Federico; Marcus, Frank I.; Abudureheman, Aierken; Rizzo, Stefania; Frigo, Anna Chiara; Bauce, Barbara; Maddalena, Francesco; Nava, Andrea; Corrado, Domenico; Grigoletto, Francesco; Thiene, Gaetano

doi:10.1093/eurheartj/ehn415

Cited by 164 publications

(99 citation statements)

References 29 publications

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“…It is surprising that arrhythmogenic RV cardiomyopathy/dysplasia, a disorder that primarily affects the RV "triangle of dysplasia," was commonly diagnosed on LV EMB. 18 These findings extend a smaller comparison study of LV and RV biopsy that found biventricular EMB has a superior diagnostic yield compared with RV EMB. 19 The strongest conclusion from these data and the other recently published LV EMB case series is that the risk of major complications from LV EMB is low (<1%) when performed by experienced operators at centers with appropriate infrastructure support.…”

Section: Article See P 1531supporting

confidence: 77%

Role of Left Ventricular Biopsy in the Management of Heart Disease

Cooper

2013

Circulation

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Section: Article See P 1531supporting

confidence: 77%

Role of Left Ventricular Biopsy in the Management of Heart Disease

Cooper

2013

Circulation

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“…Distinguishing between athlete's heart and hypertrophic or arrhythmogenic cardiomyopathy can be very challenging despite modern imaging 20 and this uncertainty may be incompletely resolved at autopsy. For example, fibro-fatty infiltration of the right ventricle may not be as specific for the diagnosis of arrhythmogenic right ventricular cardiomyopathy (ARVC) as has previously been thought, 21 whilst hypertrophic cardiomyopathy and athlete's heart may also be indistinguishable on histology.…”

Section: Inherited Versus Acquired Heart Disease-not Black and White mentioning

confidence: 98%

Can Intensive Exercise Harm the Heart?

2014

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“…[6][7][8][9][10][11] Our first patient had his genetic screening for mutations of desmosomal proteins, also his father had the same diagnosis, and the third patient had a family history of ARVD/C, and his elder brother managed by medical therapy.…”

Section: Discussionmentioning

confidence: 99%

Arrhytmogenic Right Ventricular Dysplasia/ Cardiomyopathy (ARVD/C) and Heart Transplantation: Case Series

Demirozu¹,

Küçükaksu²

2015

Turkiye Klinikleri J Cardiovasc Sci

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36rrhytmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is a heart muscle disease of unknown etiology, characterized by peculiar right ventricular (RV) involvement, has a prevalence of at least 1 in 1000 and ventricular arrhythmias, sudden death may be observed. 1Arrhytmogenic Right Ventricular Dysplasia/ Cardiomyopathy (ARVD/C) and Heart Transplantation: Case Series A AB BS ST TR RA AC CT T Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) usually originates from right ventricle, has a prevalence 1 in 1000 and leading cause of death in people aged less than 35 years of age, also desmosome mutations and family history can be seen in this disease. We reviewed the literature and described three patients with arrhythmogenic right ventricular dysplasia/ cardiomyopathy (ARVD/C). They had T wave inversion in chest leads V1 to V4 and had premature ventricular complexes of left bundle branch block and left axis deviation, or right bundle branch block (RBB) had implantable cardioverter defibrillator (ICD) implantation and fulfilled the task force criteria for diagnosis of ARVD/C. One patient had familial erythrocytosis and thrombus formation in the right atrium and the right ventricle. He was listed as status 1A and had 2 times phlebotomy during the hospitalization. The other patient had warfarin intoxication, and had hepatic congestion due to end-stage right heart failure. The third patient had a history of cerebrovascular event and had a family history of ARVD/C. All of our patients had the medical regimen for the management of ARVD/C. All of the patients were in NYHA Class III-IV while they admitted to our clinic and they had their final therapeutic option as an orthotopic heart transplantation and have a good quality of life.K Ke ey y W Wo or rd ds s: : Arrhythmogenic right ventricular dysplasia; heart transplantation Ö ÖZ ZE ET T Aritmojenik sağ ventriküler displazisi/kardiyomiyopati (ARVD/C), sağ ventrikülden orijin alır, 1000'de 1 görülme sıklığı vardır, 35 yaşından genç insanlarda en fazla ölüm sebeplerindendir. Bu hastalıkta desmozom mutasyonları ve aile hikayesi görülebilir. Biz detaylı olarak literatürü taradıktan sonra, aritmojenik sağ ventrikül displazisi/kardiyomiyopati (ARVD/C) olan 3 hastamızı sunuyoruz.V1'den V4'e kadar tüm göğüs derivasyonlarında ve sol dal bloğu ile prematür ventrikül atımlar ve sol aks deviasyonu ve sağ dal bloğu tespit edilmesi üzerine hastalara kardiyoverter implantable defibrilatör (ICD) implante edildi. Hastalarımızdan biri 1A statüsünde idi ve hastanede bulunduğu sürede 2 kez filebotomi yapıldı. Diğer hastanın warfarin intoksikasyonu ve sağ kalp yetmezliğine bağlı karaciğer konjesyonu mevcuttu. Üçüncü hastamızın da daha önce geçirilmiş serebrovasküler olayı ve ARVD/C aile hikayesi vardı. Tüm hastalarımız ARVD/C yönelik maksimum medikal tedavilerini almışlardı ve kliniğimize başvurduklarında New York Heart Association (NYHA) Klass III-IV idiler ve onlar için en iyi tedavi kalp nakli olmaları idi. Ortotopik kalp naklini olduktan sonra daha iyi bir yaşam ...

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Quantitative assessment of endomyocardial biopsy in arrhythmogenic right ventricular cardiomyopathy/dysplasia: an in vitro validation of diagnostic criteria

Cited by 164 publications

References 29 publications

Role of Left Ventricular Biopsy in the Management of Heart Disease

Role of Left Ventricular Biopsy in the Management of Heart Disease

Can Intensive Exercise Harm the Heart?

Arrhytmogenic Right Ventricular Dysplasia/ Cardiomyopathy (ARVD/C) and Heart Transplantation: Case Series

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