Quantitative aspects of inductively coupled plasma mass spectrometry

Bulska, Ewa; Wagner, Barbara

doi:10.1098/rsta.2015.0369

Cited by 39 publications

(19 citation statements)

References 75 publications

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“…In this study, following other published studies (Jimenez‐Sanchez et al . 2019), scanning electron microscopy with energy‐dispersive X‐ray analysis was carried out to evaluate the surface of all three sealers, and inductively coupled plasma‐mass spectrometry (Bulska & Wagner 2016) was conducted to monitor the ion release of the sealer extracts. In this study, BCS and BCHiF had the same elemental composition.…”

Section: Discussionmentioning

confidence: 99%

Chemical composition and bioactivity potential of the new Endosequence BC Sealer formulation HiFlow

et al. 2020

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AimTo evaluate in a laboratory setting the effects of Endosequence BC Sealer HiFlow (Brasseler USA, Savannah, GA, USA), a novel calcium silicate‐based sealer developed for use in warm canal filling techniques, on human periodontal ligament stem cells (hPDLSCs).MethodologyEluates of EndoSequence BC Sealer HiFlow (BCHiF) (Brasseler USA), EndoSequence BC Sealer (BCS) (Brasseler USA) and AH Plus (AHP) (Dentsply DeTrey GmbH, Konstanz, Germany) were placed in contact with hPDLSCs. The characterization of the chemical elements of the root canal sealers was assessed using scanning electron microscopy and energy‐dispersive X‐ray analysis (SEM‐EDX). Inductively coupled plasma‐mass spectrometry (ICP‐MS) was used to determine the ion release of the sealers. MTT assay and wound healing techniques were used to determine cell viability and migration, respectively. Cell morphology and cell attachment were assessed using a direct contact technique of hPDLSCs onto the surface of the sealers and analysed by SEM. The bioactivity potential was carried out with the Alizarin Red and qPCR testing methods. The statistical differences were evaluated using one‐way anova and Tukey’s test (P < 0.05).ResultsICP‐MS and EDX revealed significantly more zirconium in BCHiF than BCS (P < 0.05), whereas BCS had slightly higher levels of Ca2+ than BCHiF (P < 0.05). The cell viability assay revealed no relevant differences between BCS and BCHiF when compared with the control group (P > 0.05). Both BCS and BCHiF had similar rates of cell migration to the control group at 24 and 48 h. Cell morphology and adhesion capacity were also similar for BCS and BCHiF groups, whilst the AHP group was associated with reduced adhesion capacity. The Alizarin Red assay revealed a significant difference between the BCS and the control group (P < 0.001), as well as for the BCHiF group (P < 0.001). Finally, BCS and BCHiF promoted overexpression of osteo/cementogenic genes.ConclusionsIn general, EndoSequence BC Sealer HiFlow possesses suitable biological properties to be safely used as a root canal filling material and promote increased expression of oste/cementogenic genes by hPDLSCs.

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Section: Discussionmentioning

confidence: 99%

Chemical composition and bioactivity potential of the new Endosequence BC Sealer formulation HiFlow

et al. 2020

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“…The ionization instability may be rather easily accounted for by internal standardization (Vanhaecke and Degryse, 2012). The major benefit of liquid sample ICP‐MS is the possibility to use simple “matrix‐free” ion standards which in certain cases may be applied for direct analysis of solids through the use of LA or electrothermal vaporization (ETV) approaches (Miliszkiewicz, Walas, & Tobiasz, 2015; Bulska & Wagner, 2016; Limbeck, Bonta, & Nischkauer, 2017). In LA‐ICP‐MS (the primary variant of ICP‐MS for the analysis of solids—see Section V), the matrix effects may be considerable due to laser sputtering and aerosol formation (Miliszkiewicz, Walas, & Tobiasz, 2015; Shazzo & Karpov, 2016).…”

Section: Ionization Of N O F CL and Br In Different Mass Spectrometry Techniquesmentioning

confidence: 99%

Mass Spectrometry‐based Techniques for Direct Quantification of High Ionization Energy Elements in Solid Materials—challenges and Perspectives

Gubal

Chuchina

Sorokina

et al. 2020

Mass Spectrometry Reviews

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The determination of nonmetals, first of all, the most electronegative ones—nitrogen, oxygen, fluorine, chlorine, and bromine, poses the highest challenge for element analysis. These elements are characterized by high reactivity, volatility, high ionization energy, and the absence of intensive spectral lines in the optical spectral range. Conventional techniques of their quantification include considerable “wet chemistry” stages so the application of these techniques for the solid sample is highly laborious and prone to uncontrollable uncertainties. Additionally, current development in material science and other areas requires the quantification of the elements at lower levels with good sensitivity. Owing to their robustness and flexibility, mass spectrometry techniques provide vast possibilities for the quantification, spatial and isotopic analysis, including the solutions for direct analysis of solids. The current review focuses on the application of major mass spectrometric techniques for the quantification of N, O, F, Cl, and Br in solid samples. The following techniques are mainly considered: thermal ionization mass spectrometry (TIMS), isotope‐ratio MS (IRMS), secondary ion MS (SIMS), inductively coupled plasma MS (ICP‐MS), and glow discharge MS (GDMS); as the most accessible and widely applied for the purpose. General ionization issues, advantages, limitations, and novel methodological solutions are discussed. © 2020 John Wiley & Sons Ltd.

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“…Laser ablation inductively coupled plasma mass spectrometry is a highly sensitive, reliable technique for trace metal and isotope analysis with a typical limit of detection in the order of ng/kg to pg/kg for many elements in a variety of matrices. 13,[70][71][72][73][74] This technique is not as widely accessible as SEM-EDS and perhaps XPS, but is user friendly in the sense that sample preparation is extremely minimal.…”

Section: Laser Ablation Inductively Coupled Plasma Mass Spectrometrymentioning

confidence: 99%

Spectroscopic and Spectrometric Approaches for Assessing the Composition of Embedded Metals in Tissues

et al. 2021

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Many medical devices contain metals that interface with the body. Additionally, embedded metal fragments from military wounds are typically not removed, to avoid the risk of morbidity associated with invasive surgery. The long-term health consequences of many of these materials are not thoroughly understood. To this end, we have exposed rats for up to one year to implanted single-element metal pellets of any one of Al, Co, Cu, Fe, Ni, Pb, Ta, or W. Various tissues were harvested and flash frozen for analysis of their metal distribution. We discuss approaches to most thoroughly and reliably evaluate the distribution of metal in these tissues. The path to the most appropriate analytical technique took us through extensive examination of the tissues using Scanning Electron Microscopy with Energy Dispersive X-ray Spectroscopy (SEM-EDS), X-ray Photoelectron Spectroscopy (XPS), and Laser Ablation Inductively Coupled Plamsa Mass Spectrometry (LA-ICP-MS). Though any one of these methods is highly relied upon in surface chemistry analysis, LA-ICP-MS alone showed presence of metal in the tissue. This information will help build robust methods to bridge the gap in our understanding of biosolubility and distribution of embedded metal throughout the body.

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Quantitative aspects of inductively coupled plasma mass spectrometry

Cited by 39 publications

References 75 publications

Chemical composition and bioactivity potential of the new Endosequence BC Sealer formulation HiFlow

Chemical composition and bioactivity potential of the new Endosequence BC Sealer formulation HiFlow

Mass Spectrometry‐based Techniques for Direct Quantification of High Ionization Energy Elements in Solid Materials—challenges and Perspectives

Spectroscopic and Spectrometric Approaches for Assessing the Composition of Embedded Metals in Tissues

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