“…In 1981, Nachtmann et al compiled the then current knowledge of the physical, chemical, and pharmaceutical characteristics of OT, noting the importance of formulation pH on the rate of degradation . In the following years, several methods were published in which LC‐UV was used to determine OT quality in pharmaceutical dosage forms , including the US and EU pharmacopoeias . In these stability‐indicating methods, OT was resolved from its pH‐, heat‐, light‐, and oxidative‐stress degradation products.…”