Quantification of phytochemical constituents and in-vitro antioxidant activity of Mesua ferrea leaves

D, Narender Prasad; Rao, Battu Ganga; Rao, E. Sambasiva; Talluri, Mallikarjuna Rao

doi:10.1016/s2221-1691(12)60269-x

Cited by 31 publications

(13 citation statements)

References 6 publications

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“…Recent pharmacognosy analysis on Mesua ferrea leaf and fruit extracts showed both methanolic extracts to exhibit good antibacterial activity towards Staphylococcus aureus [11]. Previous research papers on Mesua species have shown that these plants exhibit many biological activities such as antioxidant [12–14], hepatoprotective [12], antiarthritic [15], immunomodulatory [16], antibacterial [17], antiacetylcholinesterase (AChE) [18], and larvicidal [19] activities, as well as antiproliferative effects [9, 20–22]. These plants were thus selected for our pharmacological investigation.…”

Section: Introductionmentioning

confidence: 99%

In VitroCytotoxic, Antioxidant, and Antimicrobial Activities ofMesua beccariana(Baill.) Kosterm.,Mesua ferreaLinn., andMesua congestifloraExtracts

Teh

Mah³

et al. 2013

BioMed Research International

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The in vitro cytotoxicity tests on the extracts of Mesua beccariana, M. ferrea, and M. congestiflora against Raji, SNU-1, HeLa, LS-174T, NCI-H23, SK-MEL-28, Hep-G2, IMR-32, and K562 were achieved using MTT assay. The methanol extracts of Mesua beccariana showed its potency towards the proliferation of B-lymphoma cell (Raji). In addition, only the nonpolar to semipolar extracts (hexane to ethyl acetate) of the three Mesua species indicated cytotoxic effects on the tested panel of human cancer cell lines. Antioxidant assays were evaluated using DPPH scavenging radical assay and Folin-Ciocalteu method. The methanol extracts of M. beccariana and M. ferrea showed high antioxidant activities with low EC50 values of 12.70 and 9.77 μg/mL, respectively, which are comparable to that of ascorbic acid (EC50 = 5.62 μg/mL). Antibacterial tests were carried out using four Gram positive and four Gram negative bacteria on Mesua beccariana extracts. All the extracts showed negative results in the inhibition of Gram negative bacteria. Nevertheless, methanol extracts showed some activities against Gram positive bacteria which are Bacillus cereus, methicillin-sensitive Staphylococcus aureus (MSSA), and methicillin-resistant Staphylococcus aureus (MRSA), while the hexane extract also contributed some activities towards Bacillus cereus.

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Section: Introductionmentioning

confidence: 99%

In VitroCytotoxic, Antioxidant, and Antimicrobial Activities ofMesua beccariana(Baill.) Kosterm.,Mesua ferreaLinn., andMesua congestifloraExtracts

Teh

Mah³

et al. 2013

BioMed Research International

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“…Preliminary qualitative phytochemical analysis made for the crude extract of D. salina revealed the presence of alkaloids, flavonoids, saponins, tannins, terpenoids and phenols. They are reported to have many biological and therapeutic properties (Prasad et al, 2012;Anusha and Bai, 2017) so this microalgae is expected to have many medicinal uses. From this table we can declare that tannins not detected with n-hexane solvent.…”

Section: Phytochemical Screeningmentioning

confidence: 99%

Minimum Inhibitory Concentration of Marine Microalgae Dunaliella salina on Fish Pathogenic Bacteria Edwardsiella tarda

Rusmawanto

Prajitno

Yuniarti

2019

RJLS

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Dunaliella salina is a type of marine microalgae. The objective of this research were investigated the effect of D. salina to inhibit the growth of E. tarda. The method used in this study was examined antibacterial activity of D. salina using disc diffusion and co culture test. The secondary metabolite compound in D. salina was tested using phytochemical screening and FTIR methods. The results obtained D. salina extracted using n-hexane showed the best activity for inhibiting the growth of E. tarda. Minimum concentration of 100 mg.L -1 crude extract can inhibit E. tarda with a total of bacterial colonies 137x10 11 CFU.mL -1 . The phytochemical test results showed that D. salina extract using n-hexane contained flavonoids, saponins, alkaloids, terpenoids and phenols. The FTIR analysis showed phenol and carotene compounds are one of the secondary metabolites that can be used as antibacterial. It can be concluded that the extract has strong antibacterial activity against E. tarda and potentially as antibacterial in aquaculture.

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“…100-500 µL of extract was taken into different test tubes, make the volume 0.5 mL with phosphate buffer of pH 6.8 Antimicrobial activity was performed according to Narendra et al [18].…”

Section: Inhibition Of Alpha Amylase Enzymementioning

confidence: 99%

Detection of Phytoconstituents of Medicinal Plant Terminalia arjuna Using Chromatographic Techniques

Rr¹,

Sl²,

Date³

et al. 2017

J Chromatogr Sep Tech

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Quantification of phytochemical constituents and in-vitro antioxidant activity of Mesua ferrea leaves

Cited by 31 publications

References 6 publications

In VitroCytotoxic, Antioxidant, and Antimicrobial Activities ofMesua beccariana(Baill.) Kosterm.,Mesua ferreaLinn., andMesua congestifloraExtracts

In VitroCytotoxic, Antioxidant, and Antimicrobial Activities ofMesua beccariana(Baill.) Kosterm.,Mesua ferreaLinn., andMesua congestifloraExtracts

Minimum Inhibitory Concentration of Marine Microalgae Dunaliella salina on Fish Pathogenic Bacteria Edwardsiella tarda

Detection of Phytoconstituents of Medicinal Plant Terminalia arjuna Using Chromatographic Techniques

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