Quantification of Myocardial Area at Risk: Validation of Coronary Angiographic Scores With Cardiovascular Magnetic Resonance Methods

Moral, Sergio; Rodríguez-Palomares, José F.; Descalzo, M.; Martí, Gerard; Pineda, Víctor; Otaegui, Imanol; Blanco, Bruno García del; Evangelista, Artur; Garcı́a-Dorado, David

doi:10.1016/j.rec.2012.04.014

Cited by 12 publications

(8 citation statements)

References 34 publications

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“…Our study results demonstrate modest but similar correlation (r = 20.34, P , .0001) with FFR as had been described for conventional angiography (11). We also demonstrated that the score is highly reproducible, with minimal interobserver variability, which is in agreement with previous reports (11,18).…”

Section: Discussionsupporting

confidence: 91%

“…Table E1 (online) demonstrates the derivation of the APPROACH score, as has been previously described (17). Furthermore, it has been validated with cardiac MR imaging methods to quantify the myocardial area at risk after myocardial infarction (18). The modified score takes into account the location of the lesion (proximal, middle, or distal) and the dominance and size of the secondary branches and provides an estimate of the percentage of supplied myocardium beyond the considered coronary lesion (17).…”

Section: Modified Approach Scorementioning

confidence: 99%

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The ASLA Score: A CT Angiographic Index to Predict Functionally Significant Coronary Stenoses in Lesions with Intermediate Severity—Diagnostic Accuracy

Ko¹,

Wong²,

Cameron³

et al. 2015

Radiology

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Section: Discussionsupporting

confidence: 91%

Section: Modified Approach Scorementioning

confidence: 99%

The ASLA Score: A CT Angiographic Index to Predict Functionally Significant Coronary Stenoses in Lesions with Intermediate Severity—Diagnostic Accuracy

Ko¹,

Wong²,

Cameron³

et al. 2015

Radiology

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“…Angiographic scoring systems have been developed to include both the severity of coronary stenosis and the volume of the myocardium subtended distal to the lesion. Moral et al previously demonstrated that the BARI score accurately estimates the amount of the jeopardized myocardium based on the evaluations of infarct size using cardiac MRI in patients with ST-segment elevation myocardial infarction [12]. The myocardial jeopardy score was calculated from an anatomic representation of the size and distribution of the coronary arteries [12,16].…”

Section: Discussionmentioning

confidence: 99%

A novel coronary angiographic index for predicting correlation between fractional flow reserve and resting full-cycle ratio

Ohtani,

Ueshima,

Kawakami

et al. 2023

Coronary Artery Disease

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Objectives The discordant results between fractional flow reserve (FFR) and resting full-cycle ratio (RFR) and the influence of angiographic characteristics on their correlation have not been sufficiently investigated. We aimed to identify angiographic characteristics that can predict FFR and RFR correlations using a novel angiographic scoring system. Methods This retrospective analysis included 220 patients with 252 intermediate coronary lesions assessed using FFR and RFR. Each branch distal to the target lesion was scored based on the vessel diameter (0 points: < 1.5 mm, 1 point: 1.5–2.0 mm, and 2 points: > 2.0 mm) measured using quantitative coronary angiography. The angiographic score was calculated by adding these scores. Results In a propensity score-matched cohort including 84 lesions (42 lesions in each low-and high-angiographic score group), the correlation between FFR and RFR in the high-angiographic score group (>4) was weaker than that in the low-score group (≤4) (Spearman’s correlation: r = 0.44 vs. r = 0.80, P < 0.01). Considering a threshold of functional myocardial ischemia as FFR ≤ 0.80 and RFR ≤ 0.89, the low-angiographic score group showed a significantly lower discordance rate of abnormal FFR/normal RFR than the high-angiographic score group (7.1% vs. 23.8%, P = 0.03), whereas the discordance rates of normal FFR/abnormal RFR were similar in both groups (7.1% vs. 9.5%, P = 0.69). Conclusion This retrospective analysis highlights the influence of angiographic characteristics on the correlation between FFR and RFR. Our simple angiographic assessment method may be useful for interpreting physiological evaluations in daily clinical practice.

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“…Image analysis was conducted on a workstation (Cvi42, Circle Cardiovascular Imaging Inc., Calgary, Alberta, Canada) by 2 cardiologists specialized in cardiac imaging. Data on reproducibility, inter-and intraobserver variability have been previously published [32].…”

Section: Cmr Protocolmentioning

confidence: 99%

Effect of COMBinAtion therapy with remote ischemic conditioning and exenatide on the Myocardial Infarct size: a two-by-two factorial randomized trial (COMBAT-MI)

et al. 2021

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Manuscript-changes in yellowClick here to access/download;Manuscript;MANUSCRIPT COMBAT MI-BRC-DEF_yellow marked.docx Click here to view linked References Acknowledgements: The COMBAT-MI trial was conceived, designed and led by Prof. David Garcia-Dorado and represents the last contribution of his scientific and medical career dedicated entirely to the search for new and effective cardioprotective strategies that can benefit patients with ischemic heart disease. With this article we want to pay a heartfelt tribute to his memory and express our gratitude to him. The authors also want to thank Prof. Aurora García-Dorado for her valuable and expert assistance in the statistical analysis. The trial was sponsored with a grant from Instituto de Salud Carlos III (PIE 13/00027) and a grant from Generalitat de Catalunya (PERIS SLT/2381/2016).

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Quantification of Myocardial Area at Risk: Validation of Coronary Angiographic Scores With Cardiovascular Magnetic Resonance Methods

Cited by 12 publications

References 34 publications

The ASLA Score: A CT Angiographic Index to Predict Functionally Significant Coronary Stenoses in Lesions with Intermediate Severity—Diagnostic Accuracy

The ASLA Score: A CT Angiographic Index to Predict Functionally Significant Coronary Stenoses in Lesions with Intermediate Severity—Diagnostic Accuracy

A novel coronary angiographic index for predicting correlation between fractional flow reserve and resting full-cycle ratio

Effect of COMBinAtion therapy with remote ischemic conditioning and exenatide on the Myocardial Infarct size: a two-by-two factorial randomized trial (COMBAT-MI)

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