Quantification of left ventricular volumes and ejection fraction using freehand transthoracic three-dimensional echocardiography: Comparison with magnetic resonance imaging

Mannaerts, Herman F.J.; Heide, J.A. van der; Kamp, Otto; Papavassiliu, Theano; Marcus, J. Tim; Beek, Aernout M.; Rossum, Albert C. van; Twisk, Jos W. R.; Visser, Cees A.

doi:10.1067/mje.2003.7

Cited by 83 publications

(50 citation statements)

References 28 publications

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“…17,19 A similar study with EchoGen showed a small but significant decrease in LV end-diastolic volume, and no change in LV endsystolic volume and ejection fraction measurements. 23 Conceivably, the difference in LV end-systolic volume measurements between the studies may represent relatively more destruction of ultrasound contrast agent in the intertrabecular zone in the EchoGen study.…”

Section: Discussionmentioning

confidence: 99%

“…23 The study was approved by the medical ethics committee of our institution and all patients provided prior written informed consent. One 3DE acquisition was performed immediately before and one during continuous intravenous ultrasound contrast infusion.…”

Section: Methodsmentioning

confidence: 99%

“…The ultrasound platform was interfaced with a TomTec Compact 3D Cardiac Imaging system (TomTec GmbH, Munich, Germany) as described earlier. 23 Briefly, a pyramidal 3DE dataset was acquired from the apical acoustic window by making a fan-like 120°sweep with the 2DE transducer from the epicardial anterior wall to the epicardial posterior wall or vice-versa, with a spatial locator mounted on top of the transducer. Using ECG triggering, consecutive imaging planes encompassing a full cardiac cycle were thus acquired at known spatial orientations along the 120°sweep.…”

Section: Three-dimensional Echocardiographymentioning

confidence: 99%

“…The magnitude of the reproducibility as observed in this study was comparable to earlier unenhanced studies performed by our group. 23 …”

Section: Reproducibilitymentioning

confidence: 99%

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Contrast-enhanced versus non-enhanced three-dimensional echocardiography of left ventricular volumes

Heide

Mannaerts²,

Yang³

et al. 2008

NHJL

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Contrast-enhanced versus non-enhanced three-dimensional echocardiography of left ventricular volumesBackground. In three-dimensional echocardiography (3DE), individual endocardial trabeculae are not clearly visible necessitating left ventricular (LV) volumes to be measured by tracing the innermost endocardial contour. Ultrasound contrast agents aim to improve endocardial definition, but may delineate the outermost endocardial contour by filling up intertrabecular space. Although measurement reproducibility may benefit, there may be a significant influence on absolute LV volume measurements. Methods. Twenty patients with a recent myocardial infarction and good ultrasound image quality underwent 3DE using the TomTec Freehand method before and during continuous intravenous contrast infusion. LV volumes were measured offline using TomTec Echo-Scan software. Results. The use of contrast enhancement increased end-diastolic (110±35 vs. 144±53 ml; p<0.01) and end-systolic volume measurements (68±31 vs. 87±45 ml; p<0.01) significantly compared with non-contrast; the ejection fraction remained unchanged (40±13 vs. 41±14%, p=NS). Measurement reproducibility did not improve significantly, however. Conclusion. Volumes measured by 3DE are significantly larger when ultrasound contrast is used. Possibly, intertrabecular space comprises a substantial part of the LV cavity. In the presence of an adequate apical acoustic window, ultrasound contrast does not improve LV volume measurement reproducibility. (Neth Heart J 2008;16:47-52.)

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Three-dimensional Echocardiographymentioning

confidence: 99%

“…The magnitude of the reproducibility as observed in this study was comparable to earlier unenhanced studies performed by our group. 23 …”

Section: Reproducibilitymentioning

confidence: 99%

See 2 more Smart Citations

Contrast-enhanced versus non-enhanced three-dimensional echocardiography of left ventricular volumes

Heide

Mannaerts²,

Yang³

et al. 2008

NHJL

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“…22 Dynamic freehand precordial three-dimensional echocardiography, as used in the present study, allows easy and fast determination of the ventricular volume by using a magnetic sensor device attached to the ultrasound probe. 23,24 Materials and methods…”

Section: Introductionmentioning

confidence: 99%

Freehand three-dimensional echocardiographic evaluation of the effect of telmisartan compared with hydrochlorothiazide on left ventricular mass in hypertensive patients with mild-to-moderate hypertension: a multicentre study

et al. 2003

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Antihypertensive efficacy, effects on left ventricular mass index (LVMI) and tolerability of telmisartan, an angiotensin II receptor blocker, were compared with those of hydrochlorothiazide (HCTZ). Adult patients with mild-to-moderate hypertension and an optimal acoustic window by two-dimensional echocardiography were randomised at baseline to 12 months' double-blind, once-daily treatment with telmisartan 80 mg or HCTZ 25 mg. Two-dimensional echocardiography and freehand precordial three-dimensional echocardiography and 24-h ambulatory blood pressure monitoring were performed at baseline and after treatment. Of the 41 telmisartan group patients and 28 HCTZ group patients, 40 and 25, respectively, completed the study. Following treatment, 24-h mean SBP (telmisartan 157 7 11 vs 133 7 7 mmHg, Po0.001; HCTZ 154 7 10 vs 144 7 11 mmHg, Po0.003) and DBP (telmisartan 96 7 6 vs 83 7 5 mmHg, Po0.001; HCTZ 95 7 7 vs 87 7 8 mmHg, Po0.003) were significantly reduced. Telmisartan produced significantly greater 24-h mean SBP and DBP reductions than HCTZ (Po0.001). LVMI was significantly reduced by telmisartan (141 7 16 vs 125 7 19 g/m 2 , Po0.001), but not by HCTZ (139 7 20 vs 135 7 22 g/m 2 ). Incidences of adverse events in both the treatment groups were low; two cases of hypokalaemia occurred with HCTZ. In conclusion, telmisartan 80 mg was well tolerated and significantly reduced SBP, DBP and LVMI after 12 months' treatment compared with HCTZ.

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Echocardiography of Aortic Stenosis

Košťál

Wiegers

2010

Cardiovascular Interventions in Clinical Practice

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Quantification of left ventricular volumes and ejection fraction using freehand transthoracic three-dimensional echocardiography: Comparison with magnetic resonance imaging

Cited by 83 publications

References 28 publications

Contrast-enhanced versus non-enhanced three-dimensional echocardiography of left ventricular volumes

Contrast-enhanced versus non-enhanced three-dimensional echocardiography of left ventricular volumes

Freehand three-dimensional echocardiographic evaluation of the effect of telmisartan compared with hydrochlorothiazide on left ventricular mass in hypertensive patients with mild-to-moderate hypertension: a multicentre study

Echocardiography of Aortic Stenosis

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