Quantification of Immunity Status of Dabur Chyawanprash - A Review Part-1 (Experimental Studies)

Sastry, J. L. N.; Gupta, Arun; Brindavanam, N. B.; Kanjilal, Satyajyoti; Kumar, Sumit; Setia, M. S.; Vedula, Sasibhushan; Srivastava, Ruchi

doi:10.15373/2249555x/feb2014/131

Cited by 6 publications

(2 citation statements)

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“…On treating dendritic cells with CP, a significant increase in the secretions of tumor necrosis factor-alpha (TNF-α) and macrophage inflammatory protein-1 alpha (MIP-1α), stimulation in interleukin-1 beta (IL-1β) levels, and rise in phagocytic activity were observed. The augmented immunity marker levels (TNF-α, IL-1β, and MIP1α), as well as enhancement of NK cells and phagocytic activity support the immunomodulatory properties of CP [117]. Clinical studies also support the immune-booster role of CP as demonstrated by reduced disease symptoms of seasonal influences, modulated IgE and immunity markers C3 and C4 levels, improved pulmonary functions, decreased cortisol levels, and increased quality of life (QoL) [118].…”

Section: Health Benefitsmentioning

confidence: 99%

Chyawanprash: A Traditional Indian Bioactive Health Supplement

et al. 2019

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Chyawanprash (CP) is an Ayurvedic health supplement which is made up of a super-concentrated blend of nutrient-rich herbs and minerals. It is meant to restore drained reserves of life force (ojas) and to preserve strength, stamina, and vitality, while stalling the course of aging. Chyawanprash is formulated by processing around 50 medicinal herbs and their extracts, including the prime ingredient, Amla (Indian gooseberry), which is the world’s richest source of vitamin C. Chyawanprash preparation involves preparing a decoction of herbs, followed by dried extract preparation, subsequent mixture with honey, and addition of aromatic herb powders (namely clove, cardamom, and cinnamon) as standard. The finished product has a fruit jam-like consistency, and a sweet, sour, and spicy flavor. Scientific exploration of CP is warranted to understand its therapeutic efficacy. Scattered information exploring the therapeutic potential of CP is available, and there is a need to assemble it. Thus, an effort was made to compile the scattered information from ancient Ayurvedic texts and treatises, along with ethnobotanical, ethnopharmacological, and scientifically validated literature, that highlight the role of CP in therapeutics. Citations relevant to the topic were screened.

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Section: Health Benefitsmentioning

confidence: 99%

Chyawanprash: A Traditional Indian Bioactive Health Supplement

et al. 2019

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“…Till now, CP has been clinically studied in diverse population in various therapeutic targets, as a preventive as well as curative preparation and as an adjunct/add on therapy or monotherapy. In animal toxicity studies (acute-dose oral toxicity, 28 days repeated-dose oral toxicity studies, and 90 days repeated-dose oral toxicity studies), CP was found to be safe in the recommended dosage for the de ned period of time as no toxicity or bodyweight loss was found with all animals surviving throughout the study duration [7].…”

Section: Age Dosage and Duration Considerations In Cp Usagementioning

confidence: 96%

Golden Ager Chyawanprash with Meager Evidential Base from Human Clinical Trials

Sharma

Kakodkar

Kabra

et al. 2022

Evidence-Based Complementary and Alternative Medicine

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Chyawanprash (CP) is one of the most revered, effective, and best-selling health supplements of Indian Ayurvedic system of medicine, which is high on the trust and health quotient among Indian consumers. CP is an ancient synergistic blend of around fifty (50) medicinal herbs, herbal extracts with jam-like consistency, traditionally used to improve respiratory health, strengthen the immune system, prevent recurrence of infections, and over the decades is known for its anti-inflammatory and antioxidant properties. With the recent growth of commercialization, this traditional preparation is gaining popularity across the world. Various pharma firms are engaged in its commercial production, and this recipe is easily available on market shelves, with a common brand name “Chyawanprash.” The consumers generally pop up with some genuine queries or doubts regarding its usage and benefits. Though CP is well-trusted traditional preparation, however, limited scientific literature is available on understanding its clinical role. This critical review discusses the general consumer queries apropos its usage, critically analyzing the reported clinical studies, perspectives, and unmapped areas for future research.

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