Quantification of Hepatic Microcirculation and Intrahepatic Shunt Perfusion During Experimental Liver Transplantation

Mehrabi, Arianeb; Kraus, T.; Otto, Gerd; Golling, M.; Gebhard, Martha Maria; Herfarth, Ch.; Klar, E.

doi:10.1016/s0041-1345(98)00052-9

Cited by 9 publications

(3 citation statements)

References 11 publications

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“…A small thermodiffusion electrode placed in the tissue continuously measures the absolute microcirculation in mL/100 g tissue per minute. It has been applied to ischemic porcine kidneys [66] and livers [67]. Furthermore, it has been clinically applied to thirty renal transplant grafts [68].…”

Section: Reducing Early Renal Graft Lossmentioning

confidence: 99%

Identification of Risk Factors for Vascular Thrombosis May Reduce Early Renal Graft Loss: A Review of Recent Literature

Keller

Jørgensen

Jespersen

2012

Journal of Transplantation

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Renal graft survival has improved over the past years, mainly owing to better immunosuppression. Vascular thrombosis, though rare, therefore accounts for up to one third of early graft loss. We assess current literature on transplantation, identify thrombosis risk factors, and discuss means of avoiding thrombotic events and saving thrombosed grafts. The incidence of arterial thrombosis was reported to 0.2–7.5% and venous thrombosis 0.1–8.2%, with the highest incidence among children and infants, and the lowest in living donor reports. The most significant risk factors for developing thrombosis were donor-age below 6 or above 60 years, or recipient-age below 5-6 years, per- or postoperative hemodynamic instability, peritoneal dialysis, diabetic nephropathy, a history of thrombosis, deceased donor, or >24 hours cold ischemia. Multiple arteries were not a risk factor, and a right kidney graft was most often reported not to be. Given the thrombosed kidney graft is diagnosed in time, salvage is possible by urgent reoperation and thrombectomy. Despite meticulous attentions to reduce thrombotic risk factors, thrombosis cannot be entirely prevented and means to an early detection of this complication is desirable in order to save the kidneys through prompt reoperation. Microdialysis may be a new tool for this.

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Section: Reducing Early Renal Graft Lossmentioning

confidence: 99%

Identification of Risk Factors for Vascular Thrombosis May Reduce Early Renal Graft Loss: A Review of Recent Literature

Keller

Jørgensen

Jespersen

2012

Journal of Transplantation

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“…However, the measurement depends on the tissue location and physiologic status of the rat. Mehrabi et al 5 found that the use of a thermodiffusion probe for the measurement of hepatic blood flow could be of future clinical value for assessing both functional and pathologic alteration after liver surgery, as well as various liver disease statuses. To study tissue perfusion in various parenchymatous organs, different noninvasive imaging modalities also exist, such as computed tomography, single-photon emission computed tomography, positron emission tomography, and magnetic resonance imaging.…”

mentioning

confidence: 99%

Gray Scale Contrast Enhancement and Quantification in Different Positions of Rabbit Liver

Dong²,

Yu³

et al. 2006

Journal of Ultrasound in Medicine

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“…Experimental transplantation surgery has been established in our department many years ago. It was developed and organized during the last years and provided an appropriate atmosphere for surgeons, fellows, and researcher to perform transplantation surgery parallel to their clinical practice .…”

Section: Discussionmentioning

confidence: 99%

Do we need animal hands‐on courses for transplantation surgery?

Golriz

Hafezi

Garoussi

et al. 2013

Clinical Transplantation

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Quantification of Hepatic Microcirculation and Intrahepatic Shunt Perfusion During Experimental Liver Transplantation

Cited by 9 publications

References 11 publications

Identification of Risk Factors for Vascular Thrombosis May Reduce Early Renal Graft Loss: A Review of Recent Literature

Identification of Risk Factors for Vascular Thrombosis May Reduce Early Renal Graft Loss: A Review of Recent Literature

Gray Scale Contrast Enhancement and Quantification in Different Positions of Rabbit Liver

Do we need animal hands‐on courses for transplantation surgery?

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