Quantification and Purification of Mangiferin from Chinese Mango (Mangifera indica L.) Cultivars and Its Protective Effect on Human Umbilical Vein Endothelial Cells under H2O2-induced Stress

Luo, Fenglei; Lv, Qiang; Zhao, Yu-Qin; Hu, Guibing; Guo-qin, Huang; Zhang, Jiukai; Sun, Chongde; Li, Xian; Chen, Kunsong

doi:10.3390/ijms130911260

Cited by 91 publications

(57 citation statements)

References 29 publications

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“…Peels are good source of mangiferin (C-glucosyl xanthone), a heat-stable and pharmacologically active phytochemical. Mangiferin possess various bioactivities, such as antiinflammation, anti-diabetic, immunomodulatory, antitumor and antioxidant (Luo et al 2012). It showed high DPPH· free-radical scavenging capacity and thus has potential in the prevention of oxidative stress-associated diseases.…”

Section: Phenolic Antioxidantsmentioning

confidence: 99%

Biotechnological Potentialities and Valorization of Mango Peel Waste: A Review

Puligundla¹,

Obulam²,

Oh³

et al. 2014

JSM

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Section: Phenolic Antioxidantsmentioning

confidence: 99%

Biotechnological Potentialities and Valorization of Mango Peel Waste: A Review

Puligundla¹,

Obulam²,

Oh³

et al. 2014

JSM

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“…According to the results presented in Table 2, mangos cultivated in Córdoba present similar values and even higher for Mangiferin content reported in different research. For example, Luo et al (2012) reported that the Mangiferin content in 11 varieties of mango pulp from China, was between 0.2 and 20 mg/100 g dry matter.…”

Section: Mangiferinmentioning

confidence: 99%

Mangiferin content, carotenoids, tannins and oxygen radical absorbance capacity (ORAC) values of six mango (Mangifera indica) cultivars from the Colombian Caribbean

Morales¹,

Zapata²,

Jaimes³

et al. 2017

J. Med. Plants Res.

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Mango is one of the tropical fruits of greater production and consumption in the world, and a rich source of bioactive compounds, with various functional properties such as antioxidant activity. In Colombia, mango's market is very broad and diverse. However, there are very few studies that determined the content of bioactive secondary metabolites. The objective of this study was to evaluated the content of different metabolites like Mangiferin, carotenoids, tannins, and the antioxidant capacity by oxygen radical absorbance capacity (ORAC) methodology of six cultivars from the Colombian Caribbean region, with total carotenoid values ranging from 24.67 to 196.15 mg of β-carotene/100 g dry pulp; 84.30 to 161.49 mg Catequine eq./100 g dry pulp for the content of condensed tannins, and 91.80 to 259.23 mg/100 g dry pulp for mangiferin content. The ORAC methodology showed important antioxidant activity results, such as the Chancleta variety with the highest value (2163.78 μmol Trolox/100 g dry pulp). In conclusion, the evaluated mango varieties had promising results as functional food of high nutraceutical value, being Chancleta, Criollo and Jobo varieties, the fruits with highest content in bioactive compounds that expressed the best antioxidant activity.

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“…One of such ingredients that have undergone close scrutiny in recent years is mangiferin (MG), a C-glucosylxanthone (Scheme 1). MG belongs to the class of yellow oxygenated heterocyclics called xanthones, whose role is well-known in medicinal chemistry [3] [4]. The extraction of this promising pharmacological ingredient from various parts of the tropical based Mangifera indica L. by different authors has been reviewed by [5].…”

Section: Introductionmentioning

confidence: 99%

Adsorptive Stripping Voltammetric Determination of Mangiferin Using an Activated Chitosan Modified Carbon Paste Electrode

Tchieno¹,

Njanja²,

Tapondjou³

et al. 2014

AJAC

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A medium molecular weight powdered chitosan modified carbon paste electrode was used to investigate the electrochemical behaviour by cyclic voltammetry of the pharmacologically-active ingredient mangiferin (MG). An irreversible system was observed, with a peak at +0.55 V (vs Ag/AgCl). The peak current increases about fourfold, at the modified electrode in comparison with that recorded at the chitosan free carbon paste electrode. This allowed the use of adsorptive stripping voltammetry to develop a simple and sensitive electroanalytical method for the determination of MG. The influence of key parameters was investigated, including the electrolysis potential, the preconcentration time, the pH of supporting electrolyte and MG concentration. Upon optimisation of these parameters, the electrode response was found to be directly proportional to the concentration of MG in the range from 2.06 × 10 −6 M to 6.74 × 10 −5 M, leading to a detection limit of 1.84 μM for 240 s preconcentration at −0.1 V. A mechanism was also proposed for the electrochemical oxidation of MG.

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Quantification and Purification of Mangiferin from Chinese Mango (Mangifera indica L.) Cultivars and Its Protective Effect on Human Umbilical Vein Endothelial Cells under H2O2-induced Stress

Cited by 91 publications

References 29 publications

Biotechnological Potentialities and Valorization of Mango Peel Waste: A Review

Biotechnological Potentialities and Valorization of Mango Peel Waste: A Review

Mangiferin content, carotenoids, tannins and oxygen radical absorbance capacity (ORAC) values of six mango (Mangifera indica) cultivars from the Colombian Caribbean

Adsorptive Stripping Voltammetric Determination of Mangiferin Using an Activated Chitosan Modified Carbon Paste Electrode

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