Quality of life: urinary bladder augmentation or substitution in children

Vajda, Péter; Kispal, Zoltan Farkas; Lenart, I; Farkas, A.; Vastyan, Attila M.; Pintér, Andrew

doi:10.1007/s00383-008-2317-3

Cited by 29 publications

(31 citation statements)

References 19 publications

(18 reference statements)

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“…Many of the studies reporting QOL in bladder exstrophy are limited in that they are retrospective studies, use nonvalidated or physician directed questionnaires, and have small sample sizes. 10,11 Wittmeyer et al recently used the generic SF-36 to assess 25 French adult patients with exstrophy, and found their QOL scores lower than the norms in general health perception and physical activity, but otherwise comparable to those of normal adults. 12 In a second study using the SF-36 Jochault-Ritz et al found French adolescent patients with exstrophy to have superior QOL scores compared to adult and child patients with exstrophy as well as the general population.…”

mentioning

confidence: 99%

Health Related Quality of Life in Adolescents with Bladder Exstrophy-Epispadias as Measured by the Child Health Questionnaire-Child Form 87

Schaeffer¹,

Yenokyan²,

Alcorn

et al. 2012

Journal of Urology

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Purpose We determined health related quality of life as reported by adolescents with bladder exstrophy or epispadias using a validated generic instrument. Materials and Methods Adolescents age 11 to 18 years with bladder exstrophy or epispadias (57) completed a validated, generic, health related quality of life instrument, the CHQ-CF87 (Child Health Questionnaire-Child Form 87). Urinary incontinence, catheterization status, and medical and surgical history data were also obtained. Mean summary scores and 95% CIs for each subdomain of the CHQ-CF87 were calculated, and descriptively compared to 2 population based samples. In our sample health related quality of life outcomes by continence status were compared using univariate and multivariate analysis. However, this analysis was limited by a small sample size. Results Mean age of the 49 patients with bladder exstrophy and the 8 with epispadias was 14.3 years, 67% were male and 81% were Caucasian. There were 31 participants who reported incontinence and the median number of lifetime surgeries was 9. The exstrophy population scored well in all subdomains of the instrument when descriptively compared to 2 large samples of adolescent populations. In our sample incontinent patients had lower scores by multivariate analysis in 7 of 10 domains and better scores in 3 of 10 domains, although these differences were not statistically significant. Conclusions Adolescents with bladder exstrophy and epispadias reported relatively good scores on the CHQ-CF87 when descriptively compared to other reference populations. This finding suggests that these children adapt well to the challenges of their condition. Analysis of the association of incontinence with health related quality of life was limited by the small sample size.

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mentioning

confidence: 99%

Health Related Quality of Life in Adolescents with Bladder Exstrophy-Epispadias as Measured by the Child Health Questionnaire-Child Form 87

Schaeffer¹,

Yenokyan²,

Alcorn

et al. 2012

Journal of Urology

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“…Bladder augmentation is believed to improve the quality of life of children or adolescents with urinary incontinence 10 . The closure of the bladder neck performed during ileocystoplasty is effective for the control of urinary incontinence.…”

Section: Resultsmentioning

confidence: 99%

Complications after bladder augmentation in children

et al. 2016

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PURPOSE:Bladder augmentation is an effective surgical procedure for increasing bladder capacity and reducing pressure on the urinary system. It is indicated for patients with anomalies such as spina bifida, myelomeningocele, urethral valve and bladder exstrophy, who progress with low tolerance of medication. CASES:This was a retrospective study conducted on pediatric patients submitted to bladder augmentation from 2000 to 2011.RESULTS: 34 patients aged 4 to 17 years were submitted to bladder augmentation, 30 of them with an ileal loop and 4 with a ureter.A continent urinary shunt was performed in 16 patients, the Mitrofanoff conduit was associated in 15, and the Macedo technique was used in one. Mean follow-up was 34.35 months (1 to 122 months). Mean creatinine was 1.5 ng/ml (0.4 to 7.5 ng/ml) preoperatively and 1.78 ng/ml postoperatively. Three patients required a renal transplant during follow-up. There was improvement or resolution of vesicoureteral reflux in 83.5% of the kidneys on the right and in 75% on the left. Bladder capacity increased, on average, from 152.5 ml to 410 ml. The main complications were vesical lithiasis in 3 patients and conduit perforation in one. CONCLUSION:Bladder augmentation showed good results in this series, preserving renal function in most of the patients.

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“…It provides a low-pressure, continent, catheterisable reservoir for urine, protects the upper tracts, markedly improves continence and enhances quality of life [1]. Urolithiasis is a complication of BA, with lifelong risk.…”

Section: Introductionmentioning

confidence: 99%

Bladder calculi in the augmented bladder: A follow-up study of 160 children and adolescents

Kisku

Sen

Karl

et al. 2015

Journal of Pediatric Urology

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Quality of life: urinary bladder augmentation or substitution in children

Abstract: Bladder augmentation or substitution significantly improved the health-related quality of life in children and young adolescents taking part in the study. The authors are planning a prospective long-term follow-up of the patients (longitudinal study) to validate the results.

Cited by 29 publications

References 19 publications

Health Related Quality of Life in Adolescents with Bladder Exstrophy-Epispadias as Measured by the Child Health Questionnaire-Child Form 87

Health Related Quality of Life in Adolescents with Bladder Exstrophy-Epispadias as Measured by the Child Health Questionnaire-Child Form 87

Complications after bladder augmentation in children

Bladder calculi in the augmented bladder: A follow-up study of 160 children and adolescents

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