Quality of life outcome measures using University of Washington questionnaire version 4 in early T1/T2 anterior tongue cancers with and without radiotherapy: A cross-sectional study

Abstract

Although locoregional control and disease-free survival are the major treatment-related endpoints for cancer management, QOL outcome measures have to assess to determine the impact of a treatment modality on patients well-being and for better rehabilitation of cancer-free patients.

Mastication in health‐related quality of life in patients treated for oral cancer: A systematic review

“…); 6 = Ghai et al (2021) ( I : T1 without RT, II : T2 without RT, III : T1 and T2 with RT); 7 = Gu et al (2021) ( I : ND with submandibular gland preservation, II : conventional ND); 9 = Larson et al (2021) ( I : lateral FOM, II : anterior FOM, III : alveolar ridge with FOM); 11 = Li et al (2016) ( I : PMMF, II : RFFF); 12 = Li et al (2016) ( I : RT pre‐Tx, II : RT post‐Tx, III : RT pre‐ and post‐Tx, IV : no RT); 14 = Rogers et al (2004) ( I : nil, II : rim res., III : segment res. ); 16 = Sakthivel et al (2017) ( I : surgery, II : adjuvant therapy); 17 = Seferin et al (2022) ( I : sentinel lymph node biopsy, II : cervical ND levels I–III); 21 = Wu et al (2020) ( I : classic ALTFF, II : chimeric ALTFF); 22 = Yan et al (2017) ( I : long‐term survivors, II : non‐survivors); 24 = Yuan et al (2016) ( I : RFFF, II : ALTFF); 25 = Yue et al (2018) ( I : tongue, II : other, III : no rec., IV : rec. ); 26 = Zhang et al (2013) ( I : ≤40 years, II : ≥40 years).…”

“…The MINORS quality scores of non‐comparative studies ranged from 44% (Vakil et al, 2012) to 69% (Fang et al, 2013; Vora et al, 2017; Zhang et al, 2020), with an average of 60%. The MINORS quality scores of comparative studies ranged from 54% (Ochoa et al, 2021; Sakthivel et al, 2017) to 75% (Ghai et al, 2021; Gu et al, 2021; Wu et al, 2020; Yan et al, 2017; Zhang et al, 2013; Zhang et al, 2020), with an average of 67%.…”

“…The percentage of patients considering chewing as one of the three most important domains of the UW‐QoL differed between 33.3% (second rank) (Fang et al, 2013) and 94.1% (first rank) (Li et al, 2013). Other studies only reported the rank of the chewing domain: first rank (Li et al, 2016; Vora et al, 2017; Yue et al, 2018), second rank (Sakthivel et al, 2017) and third rank (Sakthivel et al, 2017). Soares et al (2018) used an alternative way to present outcomes.…”

“…In some studies, patients administered the questionnaire at least once pre‐ and post‐treatment (Agarwal et al, 2014; Yan et al, 2017). Patients in other studies administered the questionnaire only once post‐treatment (Bekiroglu et al, 2011; Devine et al, 2001; Fang et al, 2013; Fang et al, 2014; Ghai et al, 2021; Gu et al, 2021; Larson et al, 2021; Li et al, 2013; Li et al, 2016; Ochoa et al, 2021; Sakthivel et al, 2017; Seferin et al, 2022; Soares et al, 2018; Vakil et al, 2012; Vora et al, 2017; Wu et al, 2020; Yang et al, 2014; Yue et al, 2018; Zhang et al, 2013; Zhang et al, 2020). The questionnaire was administered twice post‐treatment in two studies (Rogers & Lowe, 2020; Yuan et al, 2016).…”

“…However, the type of primary treatment differed: Besides primary surgery (tumour resection), a (selective/functional) neck dissection was performed in some studies(Agarwal et al, 2014;Bekiroglu et al, 2011;Devine et al, 2001;Fang et al, 2013;Fang et al, 2014;Ochoa et al, 2021;Sakthivel et al, 2017;Seferin et al, 2022;Wu et al, 2020;Yang et al, 2014;Yue et al, 2018). Most surgical treatments included reconstruction(Devine et al, 2001;Fang et al, 2014;Ghai et al, 2021;Gu et al, 2021;Hoene et al, 2021;Larson et al, 2021;Li et al, 2013;Rogers et al, 2004;Rogers & Lowe, 2020;Sakthivel et al, 2017;Soares et al, 2018;Vora et al, 2017;Wu et al, 2020;Yang et al, 2014;Yuan et al, 2016;Yue et al, 2018;Zhang et al, 2013;Zhang et al, 2020). Only two studies did not apply or mention adjuvant therapy(Ochoa et al, 2021;Yang et al, 2014).One study did not report any treatment details(Vakil et al, 2012).As stated in the inclusion criteria, HR-QoL outcomes were assessed in all studies by using the UW-QoL questionnaire.…”