“…In agreement with our findings, some investigators have found that long-term disease results in decline in the HRQOL in children with epilepsy (Ronen et al, 2010;Wu et al, 2010), whereas other researchers have found no difference between epilepsy duration and their HRQOL (Connolly et al, 2006;Miller et al, 2003;Mrabet, Mrabet, Zouari, & Ghachem, 2004;Yong et al, 2006). Childhood-onset epilepsy has a prolonged detrimental effect on HRQOL, not only for children and adolescents, even in adults who are without seizures and free of drugs for many years (Mathiak et al, 2010).…”