Quality of life in people with vitiligo: a systematic review and meta-analysis

Morrison, Blaise; Burden‐Teh, Esther; Batchelor, Jonathan; Mead, Emma; Grindlay, Douglas; Ratib, Sonia

doi:10.1111/bjd.15933

Cited by 47 publications

(34 citation statements)

References 9 publications

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“…However, because of the number of studies found and the theoretical difference between quality of life and psychological symptoms or disorders, it was decided it would be more appropriate to assess these outcomes separately. The systematic review on quality of life in people with vitiligo has been published . The methods used for this review were reported in accordance with the PRISMA statement …”

Section: Methodsmentioning

confidence: 99%

The prevalence of psychological comorbidity in people with vitiligo: a systematic review and meta-analysis

Osinubi

Grainge

Liu

et al. 2018

British Journal of Dermatology

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Section: Methodsmentioning

confidence: 99%

The prevalence of psychological comorbidity in people with vitiligo: a systematic review and meta-analysis

Osinubi

Grainge

Liu

et al. 2018

British Journal of Dermatology

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“…Since then, a growing body of evidence has confirmed that vitiligo has a major effect on the quality of life of patients [3,160,161,169,243,[246][247][248]. A recent meta-analysis which included 1,799 people with vitiligo confirmed the quality of life impairment in patients with Dermatology 2020;236:571-592 DOI: 10.1159/000506103 vitiligo compared with healthy controls [249]. Patients with vitiligo often have several psychological problems, such as depression, anxiety and shame which can result in low self-esteem and social isolation [161,245].…”

Section: Quality Of Lifementioning

confidence: 99%

Vitiligo: A Review

2020

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Vitiligo, a common depigmenting skin disorder, has an estimated prevalence of 0.5-2% of the population worldwide. The disease is characterized by the selective loss of melanocytes which results in typical nonscaly, chalky-white macules. In recent years, considerable progress has been made in our understanding of the pathogenesis of vitiligo which is now clearly classified as an autoimmune disease. Vitiligo is often dismissed as a cosmetic problem, although its effects can be psychologically devastating, often with a considerable burden on daily life. In 2011, an international consensus classified segmental vitiligo separately from all other forms of vitiligo, and the term vitiligo was defined to designate all forms of nonsegmental vitiligo. This review summarizes the current knowledge on vitiligo and attempts to give an overview of the future in vitiligo treatment.

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“…Non-segmental vitiligo (NSV) is an acquired chronic pigment disorder of the skin characterized by the development of patchy leukoderma, with a significant negative effect on the quality of life (1)(2)(3). NSV is the most common depigmenting disorder affecting approximately 1% of the world's population, regardless of gender, ethnicity or skin type (4).…”

Section: Introductionmentioning

confidence: 99%

Patient reported outcomes for intensified versus conventional NB-UVB treatment in non-segmental vitiligo

Uitentuis

Narayan

Wind³

et al. 2018

Journal of Dermatological Treatment

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Introduction: Treatment of non-segmental vitiligo (NSV) remains a challenge. Efficacy of NB-UVB treatment may increase with more frequent use or in combination with topical agents. Currently, data on the most effective treatment regimen lacking. Our objective is to retrospectively compare NB-UVB treatment regimens for non-segmental vitiligo. Methods: Patients with NSV treated with NB-UVB therapy were included in two time periods. Group I received NB-UVB therapy twice a week (conventional treatment) and group II received NB-UVB thrice a week, combined with topical agents (intensified treatment). Patients completed a questionnaire regarding the degree and onset of repigmentation, satisfaction and side effects. Results: Repigmentation scores did not differ significantly between the two groups. Onset of repigmentation in the first three months seemed higher in group II, but this difference was not significant (23.4% vs 51.1%; p ¼ .11). In both groups the majority of the patients were moderately to very satisfied (group I: 70.2% group II: 73.3%). The occurrence of adverse effects was comparable.Conclusions: This study indicates that conventional and intensified treatment for NSV seem to be comparable. The intensified treatment might be more effective to speed up the onset of repigmentation, but larger prospective studies are needed to objectify these findings. ARTICLE HISTORY

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Quality of life in people with vitiligo: a systematic review and meta-analysis

Cited by 47 publications

References 9 publications

The prevalence of psychological comorbidity in people with vitiligo: a systematic review and meta-analysis

The prevalence of psychological comorbidity in people with vitiligo: a systematic review and meta-analysis

Vitiligo: A Review

Patient reported outcomes for intensified versus conventional NB-UVB treatment in non-segmental vitiligo

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