Abstract:A range of psychological outcomes are common in people with vitiligo. The prevalence of anxiety was influenced by type of screening tool, suggesting the need for validation of psychological outcome screening tools in the field of dermatology.
“…An uncontrolled study of Indian adults and children found that vitiligo patients with suicidal ideation were more likely to turn to alcohol as a coping mechanism . A recent systematic review of 29 studies showed that other MH comorbidities for example adjustment disorder, substance disorder and alcohol abuse were evident in vitiligo patients . The present study found that vitiligo was associated with primary hospitalization for virtually every MH disorder examined and was more likely to be hospitalized for suicidal risk, alcohol and substance abuse.…”
Background
Vitiligo has a complex bidirectional relationship with mental health (MH) disturbances. However, little is known about the relationship between vitiligo and MH emergencies.
Objective
To examine the associations of vitiligo and MH hospitalizations in the United States.
Methods
Data from the 2002 to 2012 National Inpatient Sample were analysed, including a ~20% sample of all US hospitalizations (n = 87 053 155 children and adults). Prevalence of hospitalization for MH disorders, their length of stay (LOS) and cost of care were determined for those with vitiligo compared to those without vitiligo.
Results
Hospitalization for MH disorders occurred more commonly in those with vitiligo compared to those without vitiligo (4.17% vs. 2.18%). In multivariable logistic regression models, vitiligo was associated with higher odds of admission for any MH disorder [adjusted odds ratio (95% confidence interval): 1.69 (1.61–1.78)], including 14 of 15 MH disorders examined. Associated MH disorders included anxiety, schizophrenia, depression, suicidal risk, personality disorder, ADD/ADHD and conduct disorder, substance use disorder, childhood and adolescent psychiatric illnesses, alcohol‐related disorders, adjustment disorders, developmental disorders, impulse control disorders, history of mental health disorders and miscellaneous mental health disorders. Vitiligo patients hospitalized with any MH disorder had higher geometric‐mean (95% confidence interval) cost of inpatient care [$10 992 ($10 477–$11 507) vs. $10 082 ($9728–$10 435)] and LOS [5.6 (5.3–5.8) vs. 4.8 (4.6–4.9); P < 0.0001] compared to those without vitiligo, with $10.5 million excess annual costs from hospitalization with MH disorders in persons with vitiligo.
Conclusions
Persons with vitiligo had increased hospitalization for multiple MH disorders, which were associated with a considerable cost burden.
“…An uncontrolled study of Indian adults and children found that vitiligo patients with suicidal ideation were more likely to turn to alcohol as a coping mechanism . A recent systematic review of 29 studies showed that other MH comorbidities for example adjustment disorder, substance disorder and alcohol abuse were evident in vitiligo patients . The present study found that vitiligo was associated with primary hospitalization for virtually every MH disorder examined and was more likely to be hospitalized for suicidal risk, alcohol and substance abuse.…”
Background
Vitiligo has a complex bidirectional relationship with mental health (MH) disturbances. However, little is known about the relationship between vitiligo and MH emergencies.
Objective
To examine the associations of vitiligo and MH hospitalizations in the United States.
Methods
Data from the 2002 to 2012 National Inpatient Sample were analysed, including a ~20% sample of all US hospitalizations (n = 87 053 155 children and adults). Prevalence of hospitalization for MH disorders, their length of stay (LOS) and cost of care were determined for those with vitiligo compared to those without vitiligo.
Results
Hospitalization for MH disorders occurred more commonly in those with vitiligo compared to those without vitiligo (4.17% vs. 2.18%). In multivariable logistic regression models, vitiligo was associated with higher odds of admission for any MH disorder [adjusted odds ratio (95% confidence interval): 1.69 (1.61–1.78)], including 14 of 15 MH disorders examined. Associated MH disorders included anxiety, schizophrenia, depression, suicidal risk, personality disorder, ADD/ADHD and conduct disorder, substance use disorder, childhood and adolescent psychiatric illnesses, alcohol‐related disorders, adjustment disorders, developmental disorders, impulse control disorders, history of mental health disorders and miscellaneous mental health disorders. Vitiligo patients hospitalized with any MH disorder had higher geometric‐mean (95% confidence interval) cost of inpatient care [$10 992 ($10 477–$11 507) vs. $10 082 ($9728–$10 435)] and LOS [5.6 (5.3–5.8) vs. 4.8 (4.6–4.9); P < 0.0001] compared to those without vitiligo, with $10.5 million excess annual costs from hospitalization with MH disorders in persons with vitiligo.
Conclusions
Persons with vitiligo had increased hospitalization for multiple MH disorders, which were associated with a considerable cost burden.
“…The clinical evaluation was done by independent dermatologists. The reaction to repigmentation therapy was based on the evaluation of doctors: excellent for 75%‐100% repigmentation, good for 50%‐75%, moderate for 25%‐50%, and mild for <25% …”
Section: Methodsmentioning
confidence: 99%
“…Quantitative reaction assessment was also conducted for accurate statistical assessment in a numerical proportion …”
Section: Methodsmentioning
confidence: 99%
“…Evidence indicates that an excimer laser can encourage melanocyte proliferation and migration with subsequent regimentation improvement in the therapy of vitiligo. Furthermore, this method allows the therapy of tiny, badly accessible and resistant fields, resulting in better outcomes compared to standard phototherapy …”
Background
Excimer laser therapy of vitiligo generally takes months to years to achieve excellent outcomes. Platelet‐rich plasma is an autologous preparation with a focus on various growth factors that can help with vitiligo repigmentation.
Objectives
To assess the additive effect of PRP in the therapy of vitiligo on the results of the excimer laser.
Patients and Methods
A comparative study included 52 patients (8 males and 44 females) in two groups with stable (no new lesion for 6 months), nonsegmental and symmetrical vitiligo. Group I (26 patients): The patient was treated by intradermal PRP injection and the excimer laser, while group II (26 patients) was treated with the excimer laser only. The PRP injection was repeated every 3 weeks for 4 months and excimer laser two times a week and for 16 weeks till complete response. VAS for patient's satisfaction assessment, safety assessment for complications, and follow‐up for 3 months was done. Clinical (repigmentation response) and histopathological assessment was done.
Results
There was a higher statistically significant treatment response in group I compared with group II. In addition, a statistically significant correlation between the treatment response and the lesion site in group I (P < .000). A significant difference in VAS between both groups (P < .000). Few the side effects were reported.
Conclusion
The combination of PRP and excimer laser phototherapy is an efficient vitiligo treatment as PRP increases the excimer laser impact and also improves the result.
“…Skin diseases can have considerable impact on a patient's well‐being and can evoke negative emotions such as shame, embarrassment, and stress. They can also make patients feel inferior, stigmatized, and discriminated against, particularly, if the disease develops on exposed areas of the body 7 . Vitiligo is one such disease, and it is reported that roughly 75% of vitiligo patients have a psychological disorder 3 .…”
Vitiligo is an autoimmune dermatologic disorder that causes chronic skin depigmentation, which affects an estimated 1% of the world's population. This disfiguring condition can have devastating psychological consequences on its sufferers. The field of psychodermatology examines psychiatric manifestations of dermatologic conditions. Although previous research in this area has been done on other skin disorders, no large‐scale review exists on the dermatologic‐psychiatric connection in vitiligo specifically. The current article will discuss the psychodermatology of vitiligo with an emphasis on depression, stress, and low self‐esteem. The social and cultural considerations will also be explored. Finally, the implications of these psychiatric manifestations on treatment will be discussed, with the goal of implementing early psychiatric intervention for those with vitiligo.
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