Quality of life in patients with Sjögren’s syndrome and sicca complex

Abstract

To investigate the general and oral quality of life in patients with Sjögren's syndrome (SS) and sicca complex. Forty-four patients with SS were studied consecutively, 33 were primary SS and 11 secondary SS, classified in accordance with the Vitali European criteria. The Spanish version of the Medical Outcome Short Form (36) Health Survey questionnaire (SF-36) was used to evaluate general quality of life and the Oral Health Impact Profile (OHIP-49) Spanish version to study oral quality of life. Regarding general quality of life using the SF-36, when comparing the SS and the control groups, lower scores were obtained in the SS groups in all domains and on comparing primary and secondary SS, lower scores were found for primary SS in all the subscales. With respect to oral quality of life using the OHIP-49 (all items), we found lower scores for the primary SS group with respect to the control group. Patients with primary SS present lower scores for both oral and general quality of life.

The Potential Role for Early Biomarker Testing as Part of a Modern, Multidisciplinary Approach to Sjögren’s Syndrome Diagnosis

“…Due to the range of medical complications associated with SS, it is not surprising that the disease is associated with significant impairments in quality of life [23][24][25][26][27] and functioning [25,28]. Patients with SS also have a high rate of depression [26].…”

Sicca symptoms and their impact on quality of life among very long-term survivors after hematopoietic SCT

“…This has been shown for example, for patients with Sjö gren's syndrome, a disease with the predominant finding of oral and ocular sicca symptoms. 22 Data on the occurrence of sicca syndrome and the impact on QoL among long-term survivors after allogeneic HSCT is scarce. We therefore aimed in this study to examine the prevalence of sicca syndrome in long-term survivors of HSCT and to assess its impact on QoL, compared with their HLA-identical sibling donors.…”

Qualidade de vida oral e sistemica na Sindrome de Sjogren Primaria

“…Sendo a SS uma doença sistémica com grande foco semiológico a nível oral, para profissionais de saúde revela-se importante analisar a componente oral e sistémica numa avaliação global da qualidade de vida. [9][10][11]31 Como tal, espera-se a progressão futura da investigação na área.…”

“…[1][2][3] Ao longo dos últimos anos, alguns estudos têm sido realizados de modo a aferir o impacto que a SS possui na qualidade de vida sistémica (QVS) e oral (QVO). [9][10][11] A avaliação da qualidade de vida consiste na utilização de instrumentos construídos de forma a avaliar a perspetiva do doente, os quais são traduzidos, validados e testados psicometricamente para uma cultura social específica. 12 Na análise da qualidade de vida, em pacientes com SS, destacam-se na literatura os questionários Short Form Health Survey (SF) e Oral Health Impact Profile (OHIP), que avaliam a QVS e QVO respetivamente.…”

“…12 Na análise da qualidade de vida, em pacientes com SS, destacam-se na literatura os questionários Short Form Health Survey (SF) e Oral Health Impact Profile (OHIP), que avaliam a QVS e QVO respetivamente. [9][10][11] A relação entre a QVO e QVS em pacientes com SS nunca foi estudada em Portugal. Assim sendo, este estudo surge com o objetivo de avaliar a possível correlação entre um questionário de QVO (OHIP-14), um questionário de QVS (SF-12), o fluxo salivar não estimulado (FSNE), o fluxo salivar estimulado mecanicamente (FSEM) e o índice de CPO, bem como as suas eventuais relações com a utilização de prótese removível, numa amostra da população portuguesa com Síndrome de Sjögren Primária (SSP).…”