Quality of life in non cystic fibrosis bronchiectasis(NCFB): predictors and correlation with other outcome parameters

Chaurasia, Sheetal; Reddy, Anish; Haran, Alamelu; Chawla, Pavny

doi:10.1183/1393003.congress-2017.pa3698

Cited by 1 publication

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“…The quality of life of people with bronchiectasis is negatively affected by respiratory symptoms and treatment burden. 44 Gaining some insight into the possible contribution of upper airway symptoms to health‐related quality of life highlights the value of assessment of chronic rhinosinusitis symptoms as part of clinical practice. This lends further support to studies examining the management of chronic rhinosinusitis symptoms on this important patient‐reported outcome.…”

Section: Discussionmentioning

confidence: 99%

The clinical impact of self‐reported symptoms of chronic rhinosinusitis in people with bronchiectasis

Lee

Nicolson

Bondarenko

et al. 2021

Immunity Inflam & Disease

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Background: Chronic rhinosinusitis affects 62% of adults with bronchiectasis and is linked to greater bronchiectasis severity. However, the impact of symptoms of chronic rhinosinusitis on disease-specific and cough-related quality of life is unknown. Methods:In this cross-sectional study, adults with stable bronchiectasis and chronic rhinosinusitis symptoms completed the sinonasal outcome test-22 (SNOT-22), quality of life-bronchiectasis questionnaire, and Leicester cough questionnaire. Bronchiectasis severity was assessed using the bronchiectasis severity index (BSI) and chest high-resolution computed tomography (HRCT).Results: Sixty participants with bronchiectasis (mean [SD] forced expiratory volume in 1 s of 73.2 [25.5] %predicted) were included. Greater severity of chronic rhinosinusitis symptoms (based on SNOT-22) was moderately associated with impaired cough-related quality of life (according to the Leicester cough questionnaire; all r > −.60) and impaired bronchiectasis-specific quality of life (based on the quality of life-bronchiectasis questionnaire), with impaired physical function (r = −.518), less vitality (r = −.631), reduced social function (r = −.546), greater treatment burden (r = −.411), and increased severity of respiratory symptoms (r = −.534). Chronic rhinosinusitis symptoms were unrelated to disease severity according to the BSI (r = .135) and HRCT scoring (all r < .200). The severity of chronic rhinosinusitis symptoms was not affected by sputum color (p = .417) or the presence of Pseudomonas aeruginosa colonization (p = .73). Conclusions: In adults with bronchiectasis, chronic rhinosinusitis has a consistent and negative impact on both cough-related and bronchiectasisspecific quality of life.

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Section: Discussionmentioning

confidence: 99%