Quality of life in dermatomyositis

Goreshi, Renato; Chock, Monika; Foering, Kristen; Feng, Rui; Okawa, Joyce; Rose, Mathew; Fiorentino, David; Werth, Victoria P.

doi:10.1016/j.jaad.2010.10.016

Cited by 88 publications

(107 citation statements)

References 47 publications

Supporting

Mentioning

106

Contrasting

Unclassified

Order By: Relevance

“…6,8,9,11,20–26 Across all Skindex-29 subscales, QoL for adults with facial PWS (composite score, 24.6) was lower than QoL for persons without skin disease (composite score, 9). Facial PWS was the third-lowest mean Skindex-29 score (composite score and subscore), with the emotion subscore being the most affected (mean, 34.4; SD = 25.8).…”

Section: Resultsmentioning

confidence: 93%

Quality of life in adults with facial port-wine stains

Hagen

Grey

Korta

et al. 2017

Journal of the American Academy of Dermatology

View full text Add to dashboard Cite

Background Facial port-wine stains (PWS) are considered by some an aesthetic skin problem, yet impact on quality of life (QoL) has not been objectively documented. Objective We sought to (1) characterize the effect of PWS on QoL in adults, (2) to identify the clinical and demographic factors that affect QoL, and (3) to compare our results with QoL studies in other skin conditions. Methods In total, 244 adults with facial PWS completed an online QoL survey, which included the Skindex-29 instrument. Results QoL in adults with facial PWS was diminished, especially from an emotional perspective. Variables associated with reduced QoL in all Skindex-29 subdomains included comorbid depression, limited facial mobility, and presence of other skin conditions. Persons with hypertrophy had more emotional and symptomatic impairment. The composite dermatologic-specific QoL scores were similar to those of cutaneous T-cell lymphoma, rosacea, alopecia, and vitiligo. Limitations Selection bias was a potential limitation, as participants were primarily recruited from patient support groups. Conclusion Our analysis demonstrates that the presence of a facial PWS has a significant negative impact on QoL. Dermatologists caring for patients with PWS should inquire about QoL, provide appropriate support and resources, and consider QoL when discussing treatment options and obtaining authorization for these procedures.

show abstract

Section: Resultsmentioning

confidence: 93%

Quality of life in adults with facial port-wine stains

Hagen

Grey

Korta

et al. 2017

Journal of the American Academy of Dermatology

View full text Add to dashboard Cite

show abstract

“…Mental health issues are not well described in cutaneous lupus erythematosus (CLE) and dermatomyositis (DM), though patients with CLE and DM have decreased quality of life 1,2 . Mental disorders have an increased prevalence in dermatology patients, with 10.1% and 17.2% of dermatology outpatients having clinical depression and anxiety respectively 3 .…”

Section: Research Lettermentioning

confidence: 99%

A cross-sectional study of untreated depression and anxiety in cutaneous lupus erythematosus and dermatomyositis

Achtman

Kling

Feng

et al. 2016

Journal of the American Academy of Dermatology

Self Cite

View full text Add to dashboard Cite

“…Pain is thought to be a less significant symptom than itch in patients with DM, but this study found that pain significantly improved in the responders compared to the non-responders. 3 …”

Section: Discussionmentioning

confidence: 99%

“…3 One study found that, like DM, many quality of life measures in CLE improved as skin disease activity improved. Chang et al showed that treatment of CLE skin disease activity (as measured by the CLE Disease Area and Severity Index [CLASI]) correlated with an improvement in Skindex-29 emotions and symptoms subscale scores: emotions r sp =0.39 (P=0.01) and, symptoms r sp =0.33 (P=0.04).…”

Section: Discussionmentioning

confidence: 99%

“…2 Goreshi et al observed that skin-specific quality of life measures in patients with dermatomyositis were comparable to those of patients with cutaneous lupus erythematosus (CLE) and vulvodynia, and much higher than those of many other dermatologic diseases. 3 His study also found that the physical symptoms of DM were worse than those of CLE, type 2 diabetes, clinical depression, and hypertension, and that the social and emotional symptoms of DM were worse than those of congestive heart failure, recent myocardial infarction, type 2 diabetes, and hypertension. In total, Goreshi et al found that a higher DM skin disease activity score correlated with a poorer quality of life.…”

Section: Introductionmentioning

confidence: 91%

See 1 more Smart Citation

Improvement in the cutaneous disease activity of patients with dermatomyositis is associated with a better quality of life

et al. 2014

View full text Add to dashboard Cite

Background Cutaneous dermatomyositis (DM) disease activity is associated with a decreased quality of life. Objectives This prospective study assessed if an improvement in quality of life, as measured by the Skindex-29 and patient-reported itch and pain on a 10-point visual analog scale (VAS), correlated with an improvement in cutaneous DM disease activity. Methods Patients with a completed cutaneous DM disease area and severity index (CDASI) at two visits separated by at least two months were classified into responder (n=15) and non-responder (n=30) groups according to the point change in the CDASI activity scores between visits. Responders had at least a four-point improvement in CDASI activity, indicating clinically relevant improvement. Results The change from baseline to the follow-up visit of the Skindex-29 subscale scores for the responders versus the non-responders were significantly different: emotions P=0.0047, functioning P=0.0026, and symptoms P<0.0001. The change in VAS score between responders and non-responders was also significant for itch (P=0.0135) and pain (P=0.0367). The was no significant difference between the groups in terms of disease subtype, sex, race, age, treatment for DM, smoking history, or history of malignancy within five years of DM diagnosis. Conclusions This is the first study to demonstrate that the quality of life of patients with DM improved as their cutaneous disease activity decreased.

show abstract

Quality of life in dermatomyositis

Abstract: Background-Quality of life (QoL) for patients with inflammatory skin disease can be significant, but has been evaluated in just one study in dermatomyositis (DM).

Cited by 88 publications

References 47 publications

Quality of life in adults with facial port-wine stains

Quality of life in adults with facial port-wine stains

A cross-sectional study of untreated depression and anxiety in cutaneous lupus erythematosus and dermatomyositis

Improvement in the cutaneous disease activity of patients with dermatomyositis is associated with a better quality of life

Contact Info

Product

Resources

About