Quality of life following glaucoma surgery: canaloplasty versus trabeculectomy

The results of canaloplasty (CP) and Hydrus Microstent (HM) implantation were retrospectively compared at 24 months' follow-up in a cohort of subjects referred to our Institution for uncontrolled IOP in primary or secondary (e.g., pseudoexfoliative and pigmentary) open-angle glaucoma. The outcome was labelled as “complete” success, “qualified” success, or “failure” if, two years after surgery, the eyes operated on needed “no” hypotensive medications, “some” hypotensive medications, or further glaucoma surgery to attain the target IOP, respectively. Both CP and HM implant allowed significant IOP reductions, with comparable rate of clinical success and safety profile. A slightly (albeit not significant) better trend for a “complete” clinical success was observed in the CP group.

Section: Discussionmentioning

confidence: 79%

Comparison of Surgical Outcomes between Canaloplasty and Schlemm’s Canal Scaffold at 24 Months’ Follow-Up

Gandolfi

Ungaro

Ghirardini

et al. 2016

“…In 2014, Klink and coworkers [ 27 ] assessed quality of life and patient satisfaction after canaloplasty and trabeculectomy. Patients reported a better quality of life after canaloplasty, particularly with regard to positive postoperative mood, satisfaction with outcome, and lower rates of visual and nonvisual symptoms.…”

Section: Resultsmentioning

confidence: 99%

Canaloplasty: Current Value in the Management of Glaucoma

Cagini

Peruzzi

Fiore

et al. 2016

Canaloplasty is a nonpenetrating blebless surgical technique for open-angle glaucoma, in which a flexible microcatheter is inserted within Schlemm's canal for the entire 360 degrees. When the microcatheter exits the opposite end, a 10-0 prolene suture is tied and it is then withdrawn, by pulling microcatheter back through the canal in the opposite direction. Ligation of prolene suture provides tension on the canal and facilitates aqueous outflow. The main advantage of canaloplasty is that this technique avoids the major complications of fistulating surgery related to blebs and hypotony. Currently, canaloplasty is performed in glaucoma patients with early to moderate disease and combination with cataract surgery is a suitable option in patients with clinically significant lens opacities.

“…Over a decade after the first Canaloplasty procedure was performed, evidence pertaining to the long-term efficacy and safety of this noninvasive, restorative glaucoma surgery continues to accumulate. Today, more than 50 peer-reviewed clinical studies attest to the fact that Canaloplasty is as effective as trabeculectomy in lowering intraocular pressure (IOP) and reducing dependence on medications [ 1 – 6 ].…”

Section: Introductionmentioning

confidence: 99%

Canaloplasty: A Minimally Invasive and Maximally Effective Glaucoma Treatment

Khaimi

2015

Canaloplasty is a highly effective, minimally invasive, surgical technique indicated for the treatment of open-angle glaucoma that works by restoring the function of the eye's natural outflow system. The procedure's excellent safety profile and long-term efficacy make it a viable option for the majority of glaucoma patient types. It can be used in conjunction with existing drug based glaucoma treatments, after laser or other types of incisional surgery, and does not preclude or affect the outcome of future surgery. Numerous scientific studies have shown Canaloplasty to be safe and effective in lowering IOP whilst reducing medication dependence. A recent refinement of Canaloplasty, known as ab-interno Canaloplasty (ABiC), maintains the IOP-lowering and safety benefits of traditional (ab-externo) Canaloplasty using a more efficient, simplified surgical approach. This paper presents a review of Canaloplasty indications, clinical data, and complications, as well as comparisons with traditional incisional glaucoma techniques. It also addresses the early clinical evidence for ABiC.