Canaloplasty: A Minimally Invasive and Maximally Effective Glaucoma Treatment

Khaimi, Mahmoud A.

doi:10.1155/2015/485065

Cited by 63 publications

(62 citation statements)

References 23 publications

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“…; Sato et al. , ), canaloplasty (Khaimi ; Matlach et al. ), dual‐blade trabeculectomy (New World Medical Inc., Rancho Cucamonga, CA; Seibold et al.…”

Section: Discussionmentioning

confidence: 99%

Short‐term results of microhook ab interno trabeculotomy, a novel minimally invasive glaucoma surgery in Japanese eyes: initial case series

Tanito

Sano

Ikeda

et al. 2016

Acta Ophthalmologica

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“…; Sato et al. , ), canaloplasty (Khaimi ; Matlach et al. ), dual‐blade trabeculectomy (New World Medical Inc., Rancho Cucamonga, CA; Seibold et al.…”

Section: Discussionmentioning

confidence: 99%

Short‐term results of microhook ab interno trabeculotomy, a novel minimally invasive glaucoma surgery in Japanese eyes: initial case series

Tanito

Sano

Ikeda

et al. 2016

Acta Ophthalmologica

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“…ABiC also spares conjunctival manipulation, which means that future procedures can be performed if necessary [15] and is the only MIGS to address all aspects of ocular outflow.…”

Section: Introductionmentioning

confidence: 99%

Ab interno canaloplasty for the treatment of glaucoma: a case series study

Körber¹

2018

Spektrum Augenheilkd.

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SummaryPurposeTo describe and evaluate the efficacy of ab interno canaloplasty (ABiC) in patients with primary open-angle glaucoma (POAG).MethodsThis single-center consecutive case series study included patients with cataract and open-angle glaucoma (combined procedure) and pseudophakic patients (mean age, 76 years; range, 66–83 years) with POAG who underwent ABiC using the iTrack™ 250-μm microcatheter (Ellex Medical Lasers Pty Ltd, Adelaide, Australia) to circumferentially viscodilate and intubate Schlemm’s canal without placement of a tensioning suture. The primary endpoints were mean intraocular pressure (IOP) and mean number of glaucoma medications at 1, 3, 6, 9, and 12 months postoperatively.ResultsIn total, 20 patients (20 eyes) were enrolled in the study. Mean IOP reduced from 18.5 ± 3.44 mm Hg preoperatively to 14.88 ± 2.82 mm Hg (n = 17), 13.80 ± 2.05 (n = 12), 14.57 ± 2.59 mm Hg (n = 9) and 15.47 ± 2.42 (n = 6) at 1, 3, 6 and 9 months postoperatively. The 12‑month data for two patients showed that IOP had reduced from 17 mm Hg preoperatively to 16 mm Hg in one patient and from 20 mm Hg to 13 mm Hg in the other patient. The mean number of medications was reduced from 2.4 preoperatively to 0.25 at the last follow-up visit. There was one reported complication of limited descemetolysis near the limbus by the viscoelastic during the dilatation of Schlemm’s canal. No adverse events as a result of the device were reported.ConclusionsABiC was straightforward to perform in this group of patients with minimal complications. Although initial findings from this study indicate that ABiC is comparable to conventional canaloplasty in lowering IOP and medication dependency, long-term follow-up in a large patient cohort is required to confirm the efficacy of this minimally invasive glaucoma procedure.

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“…In Ab interno Canaloplasty (ABiC ™ ) , a new procedure, the microcatheter is inserted via an ab interno incision under gonioscopy, sparing the conjunctiva and sclera and eliminating the need for a tension suture. No clinical trials are published evaluating the safety or efficacy of this surgical technique[21]. …”

Section: 0 Increasing Trabecular Outflowmentioning

confidence: 99%

Microinvasive glaucoma surgery: an evidence-based assessment

Schehlein

Kaleem

Swamy

et al. 2017

Expert Review of Ophthalmology

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Introduction The advent of Microinvasive Glaucoma Surgery (MIGS) offers a novel approach in the treatment of glaucoma with the number of procedures developing at an exciting pace. Areas Covered MIGS procedures aim to lower intraocular pressure (IOP) via four mechanisms: (1) increasing trabecular outflow, (2) increasing outflow via suprachoroidal shunts, (3) reducing aqueous production, and (4) subconjunctival filtration. A comprehensive search for published studies for each Microinvasive Glaucoma Surgery (MIGS) device or procedure was undertaken using the electronic database PubMed. Search terms included ‘minimally invasive glaucoma surgery’, ‘microincisional glaucoma surgery’, and ‘microinvasive glaucoma surgery’. A manual search for each device or procedure was also performed. After review, randomized control trials and prospective studies were preferentially included. Expert Opinion These procedures offer several benefits: an improved safety profile allowing for intervention in earlier stages of glaucoma, combination with cataract surgery, and decreased dependence on patient compliance with topical agents. Established MIGS procedures have proven efficacy and more recent devices and procedures show promising results. Despite this, further study is needed to assess the long term IOP-lowering effectiveness of these procedures. Particularly, rigorous study with more randomized control trials and head-to-head comparisons would allow for better informed clinical and surgical decision-making. MIGS offers new solutions for glaucoma treatment.

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Canaloplasty: A Minimally Invasive and Maximally Effective Glaucoma Treatment

Cited by 63 publications

References 23 publications

Short‐term results of microhook ab interno trabeculotomy, a novel minimally invasive glaucoma surgery in Japanese eyes: initial case series

Short‐term results of microhook ab interno trabeculotomy, a novel minimally invasive glaucoma surgery in Japanese eyes: initial case series

Ab interno canaloplasty for the treatment of glaucoma: a case series study

Microinvasive glaucoma surgery: an evidence-based assessment

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