Quality of Life Considerations in Endoscopic Endonasal Management of Anterior Cranial Base Tumors

Saraswathula, Anirudh; Porras, Jose L.; Mukherjee, Debraj; Rowan, Nicholas R.

doi:10.3390/cancers15010195

Cited by 4 publications

(1 citation statement)

References 102 publications

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“…Currently, facial reconstructions of patients with empty nose syndrome (ENS) have yielded satisfactory results compared with other methods [17]. Some studies [18,19] have proposed the digital reconstruction of body parts, such as the nasal airways using modeling from CT scan images and then the creation of these parts through 3D printing. Through the digital model, the analysis and computation of parameters such as pressure, velocity, and turbulent kinetic energy (TKE) can be compared with other models.…”

Section: Introductionmentioning

confidence: 99%

Computational Human Nasal Reconstruction Based on Facial Landmarks

Tuan

Thinh

2023

Mathematics

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This research presented a mathematical-based approach to the computational reconstruction of the human nose through images with anthropometric characteristics. The nasal baselines, which were generated from facial aesthetic subunits combined with the facial landmarks, were reconstructed using interpolation and Mesh adaptive direct search algorithms to generate points that would serve as the support for the layer-by-layer reconstruction. The approach is proposed as the basis for nasal reconstruction in aesthetics or forensics rather than focusing on the applications of image processing or deep learning. A mathematical model for the computational reconstruction was built, and then volunteers were the subjects of nasal reconstruction experiments. The validations based on the area errors—which are based on four samples and eight sub-regions with different values depending on the regions C1, C2, and C3 and nasal shapes of the volunteers—were measured to prove the results of the mathematical model. Evaluations have demonstrated that the computer-reconstructed noses fit the original ones in shape and with minimum area errors. This study describes a computational reconstruction based on a mathematical approach directly to facial anthropometric landmarks to reconstruct the nasal shape.

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Section: Introductionmentioning

confidence: 99%

Computational Human Nasal Reconstruction Based on Facial Landmarks

Tuan

Thinh

2023

Mathematics

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Multi‐center study on sellar reconstruction after endoscopic transsphenoidal pituitary surgery

Ali,

Leland,

Stickney

et al. 2024

Int Forum Allergy Rhinol

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IntroductionSurgical techniques for sellar reconstruction include no reconstruction, use of synthetic materials, autologous grafts, and/or vascularized flaps. The aim of this study was to conduct a multi‐center study comparing the efficacy and postoperative morbidity associated with different sellar reconstruction techniques.MethodsA retrospective chart review of patients who underwent endoscopic transsphenoidal surgery for pituitary tumors from five participating sites between January 2021 and March 2023 was performed. The variables included demographics, tumor characteristics, reconstruction technique, postoperative cerebrospinal fluid leak (CSF) leak, and 22‐item Sino‐Nasal Outcome Test (SNOT‐22) scores. Comparisons of postoperative complications, SNOT‐22 scores, and duration of surgery by type of onlay reconstruction were evaluated using Fisher's exact test, analysis of variance, and Kruskal‒Wallis test.ResultsFive hundred and one patients were identified. The median tumor size was 2.1 cm, and 64% were non‐functioning. Intraoperative CSF leak was identified in 38% of patients. A total of 89% of patients underwent onlay reconstruction: 49% were reconstructed with mucosal grafts, 35% with nasoseptal flaps, and 5% with other onlay techniques. Nasoseptal flaps were utilized more frequently in the setting of giant pituitary adenomas (>3 cm), medial cavernous sinus wall resection, and high‐flow intraoperative CSF leaks. Cases who utilized mucosal grafts had an overall shorter operating time (median: 183 min vs. 240 min; p < 0.001). Five postoperative CSF leaks were identified, and therefore, statistical analysis could not be performed for this complication.ConclusionThe effectiveness and morbidity of different sellar reconstruction techniques are comparable. Vascularized flaps were utilized more frequently in the setting of larger tumors and high‐flow intraoperative CSF leaks.

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Material Removal Mechanism and Force Modeling in Ultrasonic Vibration-Assisted Micro-Grinding Biological Bone

Sun,

Li,

Zhou

et al. 2023

Chin. J. Mech. Eng.

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Micro-grinding with a spherical grinding head has been deemed an indispensable method in high-risk surgeries, such as neurosurgery and spine surgery, where bone grinding has long been plagued by the technical bottleneck of mechanical stress-induced crack damage. In response to this challenge, the ultrasound-assisted biological bone micro-grinding novel process with a spherical grinding head has been proposed by researchers. Force modeling is a prerequisite for process parameter determination in orthopedic surgery, and the difficulty in establishing and accurately predicting bone micro-grinding force prediction models is due to the geometric distribution of abrasive grains and the dynamic changes in geometry and kinematics during the cutting process. In addressing these critical needs and technical problems, the shape and protrusion heights of the wear particle of the spherical grinding head were first studied, and the gradual rule of the contact arc length under the action of high-speed rotating ultrasonic vibration was proposed. Second, the mathematical model of the maximum thickness of undeformed chips under ultrasonic vibration of the spherical grinding head was established. Results showed that ultrasonic vibration can reduce the maximum thickness of undeformed chips and increase the range of ductile and bone meal removals, revealing the mechanism of reducing grinding force. Further, the dynamic grinding behavior of different layers of abrasive particles under different instantaneous interaction states was studied. Finally, a prediction model of micro-grinding force was established in accordance with the relationship between grinding force and cutting depth, revealing the mechanism of micro-grinding force transfer under ultrasonic vibration. The theoretical model’s average deviations are 10.37% in x-axis direction, 6.85% in y-axis direction, and 7.81% in z-axis direction compared with the experimental results. This study provides theoretical guidance and technical support for clinical bone micro-grinding.

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Quality of Life Considerations in Endoscopic Endonasal Management of Anterior Cranial Base Tumors

Cited by 4 publications

References 102 publications

Computational Human Nasal Reconstruction Based on Facial Landmarks

Computational Human Nasal Reconstruction Based on Facial Landmarks

Multi‐center study on sellar reconstruction after endoscopic transsphenoidal pituitary surgery

Material Removal Mechanism and Force Modeling in Ultrasonic Vibration-Assisted Micro-Grinding Biological Bone

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