Quality of life and its association with insomnia and clinical variables in type 2 diabetes

Jain, Akhilesh; Sharmab, Rekha; Yadavc, Neelam; Chaudhary, Pavan; Jainc, Garima; Maanju, Mukesh

doi:10.21608/epx.2018.7011

Cited by 7 publications

(14 citation statements)

References 33 publications

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“…Furthermore, in people with diabetes or hypertension, insomnia is associated with an increased mortality rate (OR 7.17 [95% CI 1.41, 36.62]) [ 12 ]. Finally, in addition to poorer health outcomes, and perhaps most important for patients, insomnia negatively affects QoL, affecting all domains of QoL questionnaires [ 13 , 14 ], compared with those with type 2 diabetes without insomnia.…”

Section: Prevalence and Health Outcomes Of Sleep Disorders In Type 2 Diabetesmentioning

confidence: 99%

Sleep disorders in people with type 2 diabetes and associated health outcomes: a review of the literature

et al. 2021

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Sleep disorders are linked to development of type 2 diabetes and increase the risk of developing diabetes complications. Treating sleep disorders might therefore play an important role in the prevention of diabetes progression. However, the detection and treatment of sleep disorders are not part of standardised care for people with type 2 diabetes. To highlight the importance of sleep disorders in people with type 2 diabetes, we provide a review of the literature on the prevalence of sleep disorders in type 2 diabetes and the association between sleep disorders and health outcomes, such as glycaemic control, microvascular and macrovascular complications, depression, mortality and quality of life. Additionally, we examine the extent to which treating sleep disorders in people with type 2 diabetes improves these health outcomes. We performed a literature search in PubMed from inception until January 2021, using search terms for sleep disorders, type 2 diabetes, prevalence, treatment and health outcomes. Both observational and experimental studies were included in the review. We found that insomnia (39% [95% CI 34, 44]), obstructive sleep apnoea (55–86%) and restless legs syndrome (8–45%) were more prevalent in people with type 2 diabetes, compared with the general population. No studies reported prevalence rates for circadian rhythm sleep–wake disorders, central disorders of hypersomnolence or parasomnias. Additionally, several cross-sectional and prospective studies showed that sleep disorders negatively affect health outcomes in at least one diabetes domain, especially glycaemic control. For example, insomnia is associated with increased HbA1c levels (2.51 mmol/mol [95% CI 1.1, 4.4]; 0.23% [95% CI 0.1, 0.4]). Finally, randomised controlled trials that investigate the effect of treating sleep disorders in people with type 2 diabetes are scarce, based on a small number of participants and sometimes inconclusive. Conventional therapies such as weight loss, sleep education and cognitive behavioural therapy seem to be effective in improving sleep and health outcomes in people with type 2 diabetes. We conclude that sleep disorders are highly prevalent in people with type 2 diabetes, negatively affecting health outcomes. Since treatment of the sleep disorder could prevent diabetes progression, efforts should be made to diagnose and treat sleep disorders in type 2 diabetes in order to ultimately improve health and therefore quality of life. Graphical abstract

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Section: Prevalence and Health Outcomes Of Sleep Disorders In Type 2 Diabetesmentioning

confidence: 99%

Sleep disorders in people with type 2 diabetes and associated health outcomes: a review of the literature

et al. 2021

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“…Five case-control studies where diabetes respondents were compared with nondiabetes patients were identified,[ 26 35 36 37 38 ] whereas the remainder of studies were cross-sectional.…”

Section: R Esultsmentioning

confidence: 99%

“…Of the reviewed studies, only 14 reported gender and QoL. Poorer QoL in women than men were reported in nine studies on T2D[ 15 23 25 31 35 37 45 46 47 ] and in one study on T1D. [ 14 ] It is of interest that three studies had reported better QoL among female respondents with diabetes when compared to their male counterparts.…”

Section: R Esultsmentioning

confidence: 99%

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Quality of Life and Diabetes in India: A Scoping Review

Aarthy

Mikocka‐Walus

Pradeepa

et al. 2021

Indian Journal of Endocrinology and Metabolism

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In recent years, numerous studies have explored the quality of life (QoL) in those with diabetes mellitus. The aim of this scoping review was to explore the current state of knowledge on QoL and its various associated factors among people with diabetes in India. Three databases were searched (PubMed, Scopus, and Medline) and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed. A total of 41 articles were included in the review. The included studies were largely conducted in the Southern states and mainly investigated individuals with type 2 diabetes. The World Health Organization Quality of Life (WHOQOL-BREF) and Short Form Health Survey (SF-36) were the instruments used most often. In general, the studies showed that people with diabetes had poorer QoL than those without diabetes, and women with diabetes reported poorer QoL than men, consistent with findings across the world. However, the studies had significant methodological flaws which limit the validity and generalizability of the findings. Therefore, there is an urgent need to conduct high-quality QoL studies which are representative of all states of India as well as different types of diabetes in India in order to address this gap in the evidence.

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“…Insomnia has been shown to be associated with QOL in various populations such as cancer patients [21], patients with Type II diabetes [22]; and epilepsy [23].…”

Section: Qol Among Adolescents Living With Hivmentioning

confidence: 99%

Psychosocial predictors of quality of life among South Africa adolescents receiving antiretroviral therapy

et al. 2018

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Minimal research has been conducted to understand the relationship between psychosocial factors, fatigue, and quality of life among adolescents living with HIV. We studied 134 South African adolescents receiving an antiretroviral therapy (ART) at community clinics to examine the relationship between fatigue, sleep disturbance, depression, anxiety, pain and quality of life. Participants reported low levels of fatigue, insomnia, distress and pain and non-problematic levels of quality of life (QOL). In the regression model, the linear combination of these variables explained 49% of the variance in quality of life. Insomnia, anxiety, and depression significantly predicted quality of life but fatigue and pain did not. Future research may address the relationship between self-reported adherence and QOL, possibly by examining the role of viral load (VL) as a mediating variable. Further research may also focus on non-adherent adolescents to understand the ways in which fatigue and other factors such as school functioning and social interaction influence QOL.

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Quality of life and its association with insomnia and clinical variables in type 2 diabetes

Cited by 7 publications

References 33 publications

Sleep disorders in people with type 2 diabetes and associated health outcomes: a review of the literature

Sleep disorders in people with type 2 diabetes and associated health outcomes: a review of the literature

Quality of Life and Diabetes in India: A Scoping Review

Psychosocial predictors of quality of life among South Africa adolescents receiving antiretroviral therapy

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