Quality of Life and Its Predictors Among Children and Adolescents With Cancer

Pan, Hsien-Ting; Wu, Li‐Min; Wen, Shu‐Hui

doi:10.1097/ncc.0000000000000433

Cited by 46 publications

(28 citation statements)

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“…Furthermore, the children complaining a discomfort of TKI-therapy reported dissatisfaction with appearance, and impaired communication problems. This nding can be explained by the experience of pain, nausea and fatigue, which impaired their ability to fully participate in physical and social activities [15,34,36] . Moreover, the change in body image caused by TKI-therapy, such as weight gain, skin rash, or skin color, causes children to develop inferiority and then refuse to socialize [8] .…”

Section: Discussionmentioning

confidence: 99%

“…Female gender, living alone, severity of the malignant disease, high intensive treatment and poor response to treatment had a negative impact on HRQoL in childhood cancer survivors [4][5][6][7][8][9][10][11][12][13][14] . Meanwhile, higher education and better communication with parents are related to higher HRQoL [15][16][17] . Unlike other cancer patients, children with CML in the chronic phase (CML-CP) mainly receive long-term oral TKIs as outpatients, enabling them to participate normally in family and school life, so their HRQoL and the associated variables may also be different.…”

Section: Introductionmentioning

confidence: 99%

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Health-related Quality of Life in Children With Chronic Myeloid Leukemia in the Chronic Phase

Zheng

Dou

Zhang

et al. 2021

Preprint

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Purpose To explore the health-related quality of life (HRQoL) and associated variables in children with chronic myeloid leukemia in the chronic phase (CML-CP) receiving tyrosine kinase inhibitors (TKIs).Methods A cross-sectional questionnaire was given to children with CML and their parents, who were <18 years at diagnosis of CML and <19 years at study. The questionnaire consisted of three parts, including demographic information, clinical information, and the Chinese version of Pediatric Quality of Life InventoryTM (PedsQL™) Cancer Module 3.0 as HRQoL questionnaire.Results 289 questionnaires were collected, and data from 207 (71.6%) respondents were analyzed. Multivariate analysis showed that children with symptoms had worse pain (-10.7; P<0.001), nausea(-17.9; P<0.001), treatment anxiety(-6.7; P=0.008), worse appearance self-assessment (-7.5; P<0.001) and communication problems(-3.9; P=0.028), and worse HRQoL(-4.1; P=0.013). Children whose mothers had low educational qualifications complained worse pain(-8.3; P=0.005), worried more about the future (-11.6; P=0.002), had poor self-assessment (-5.1; P=0.045), and worse HRQoL (-6.5; P=0.002). Children at a younger age of study when studied had more procedural anxiety (3.3; P=0.008), more cognition problems (3.4; P=0.001), and worse HRQoL (1.4; P=0.040), while increasing age at diagnosis had worse appearance self-assessment (-2.1; P=0.015) and HRQoL (-1.4; P=0.039). Other variables significantly associated with worse HRQoL included female sex and rural household registration. Parents reported more gastrointestinal disorders and worry about the future and had less concern about appearance than reported children.Conclusions This study suggests that female gender, increasing age at diagnosis, younger age at study, lower mother’s education level, and TKI-related symptoms reported were significantly-associated with worse HRQoL. Parents and children have different priorities in the HRQoL.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Health-related Quality of Life in Children With Chronic Myeloid Leukemia in the Chronic Phase

Zheng

Dou

Zhang

et al. 2021

Preprint

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“…Children with cancer were the main focus of most of studies worldwide. A cross-sectional study involved 150 children aged between 7-18 years without mental illness [19] . The study found that children aged 16-18 reported lower school functioning but more sleep and fatigue.…”

Section: Discussionmentioning

confidence: 99%

Assessment of Quality of life Among Children with Cancer, Children Undergoing Hemodialysis and Children with Thalassemia: A Comparative Study

Afifi¹,

Khamis²,

Baraka³

et al. 2020

Preprint

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Purpose This study aims to evaluate health-related quality of life among children with different chronic conditions and make a comparison among them. In addition, the study will draw a comparison between children’s perspective about their quality of life and parents’ perspective. Furthermore, the study will address the associations between quality of life with disease severity, duration and the presence of other co-morbidities. Methods This was a prospective, analytical, correlational study design in which Pediatric Quality of Life Inventory (PedsQL 4.0 generic core scale) was administered to assess quality of life on 110 children; 50 children with cancer, 30 children with thalassemia and 30 children undergoing hemodialysis. Researchers interviewed children as well as their parents. Results Results showed that children with Thalassemia had the lowest scores and suffered from poor quality of life compared to the other two groups of children. Interestingly, quality of life level among children undergoing dialysis was lower than children with cancer. However, there were marked discrepancy between child’s and parents’ answers on scale questions. The level of quality of life, in all children, were statistically significant in relation with family size, income and parents’ education. Conclusion We identified high prevalence of poor level of health-related quality of life among children included in this study. The findings support that the quality of life among children with chronic conditions should receive more attention in our local medical settings.

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“…[4567] The quality of life of children who are affected by psychosocial problems and have to cope with many stressful situations[6] is also diminishing. [89] It is for this reason that the development of psychosocial programs to support children is gaining more and more importance.…”

Section: Introductionmentioning

confidence: 99%

Intervention Protocol: Technology-Based Psychosocial Motivation for Children with Cancer and Their Parents: A Randomized Trial

Şengül

Törüner

2020

Asia-Pacific Journal of Oncology Nursing

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Objective:This experimental randomized controlled trial will be to examine the impact of a technology-based psychosocial motivation program on children and families who are being followed up on a diagnosis of cancer.Methods:The research is based on the “Transactional Model of Stress and Coping.” This study will be conducted on children with leukemia, aged 9–18 years, and their parents, who will be followed in the consolidation treatment phase in the hematology wards and outpatient clinic of a university hospital. Data collection will consist of the children's and parents' descriptive characteristic form, the Spielberger State Anxiety Inventory for Parents, the State-Trait Anxiety Inventory for Children, the Pediatric Cancer Coping Scale, the Pediatric Quality of Life Inventory, and process evaluation forms. A 10-week program will be implemented for the children in the intervention group through web-based training, coaching interviews and counseling via video mobile calls, mobile messages and children's stories, progressive muscle relaxation and breathing exercises, and imagination interventions. During the same period, parents will also receive web-based training, coaching sessions, counseling, mobile messages, and progressive muscle relaxation exercises.Results:It is thought that after the intervention the stress level of the child and the family will decrease, the coping skills of the children will improve, and their quality of life will increase.Conclusions:It is thought that the treatment process can be affected positively by providing psychosocial support to children and their families who receive cancer treatment.

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Quality of Life and Its Predictors Among Children and Adolescents With Cancer

Abstract: Routinely evaluating fatigue and school functioning in pediatric patients with cancer is warranted, as well as developing educational programs to enhance the management of fatigue and relationship issues, especially for those who were given a diagnosis recently or for late adolescents.

Cited by 46 publications

References 47 publications

Health-related Quality of Life in Children With Chronic Myeloid Leukemia in the Chronic Phase

Health-related Quality of Life in Children With Chronic Myeloid Leukemia in the Chronic Phase

Assessment of Quality of life Among Children with Cancer, Children Undergoing Hemodialysis and Children with Thalassemia: A Comparative Study

Intervention Protocol: Technology-Based Psychosocial Motivation for Children with Cancer and Their Parents: A Randomized Trial

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