Quality of Life and Cost-effectiveness of a 3-Year Trial of Lifestyle Intervention in Primary Health Care

Eriksson, Margareta; Hagberg, Lars; Lindholm, Lars; Malmgren‐Olsson, Eva‐Britt; Österlind, Jonas; Eliasson, Mats

doi:10.1001/archinternmed.2010.301

Cited by 83 publications

(58 citation statements)

References 31 publications

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“…Similar result was shown by Corby K Martin et al 2009 found significant improvement in all dimension of quality of life with exercise in sedentary postmenopausal women and improvements in quality of life were dose dependent [52]. Margareeta k Eriksson et al 2010 also found improvement in physical functioning and social functioning and reduced body pain with exercise and dietary counselling in CVD patient [53].…”

Section: Health Related Quality Of Life (Hrqol)supporting

confidence: 62%

Comparative Study on Effect of Breathing and Aerobic Exercise on General Health in Asymptomatic Population

Hota¹,

Mohanty²,

Pattanaik³

2017

IOSR JDMS

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Section: Health Related Quality Of Life (Hrqol)supporting

confidence: 62%

Comparative Study on Effect of Breathing and Aerobic Exercise on General Health in Asymptomatic Population

Hota¹,

Mohanty²,

Pattanaik³

2017

IOSR JDMS

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“…Studies (29–33) in the general population demonstrated a positive effect of physical activity on health status, physical fitness, and various metabolic measures. Randomized controlled trials (RCTs) (34–41) among adults with chronic conditions have shown a positive effect of interventions aimed to increase physical activity and incremental benefit in QALY outcomes. Change in QALY between intervention and control groups in these trials have been reported to range from 0.01 to 0.13 over 12 months.…”

Section: Discussionmentioning

confidence: 99%

Relationship of meeting physical activity guidelines with quality-adjusted life-years

Sun¹,

Song²,

Manheim³

et al. 2014

Seminars in Arthritis and Rheumatism

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Objective The Quality Adjusted Life Year (QALY) is a standard outcome measure used in cost-effectiveness analyses. This study investigates whether attainment of federal physical activity guidelines is associated with higher QALY estimates among adults with or at increased risk for knee osteoarthritis. Methods This is a prospective study of 1794 Osteoarthritis Initiative participants. Physical activity was measured using accelerometers at baseline. Participants were classified as 1) Meeting Guidelines (≥150 minutes of moderate-to-vigorous [MV] activity per week acquired in sessions ≥10 minutes), 2) Insufficiently Active (≥1 MV session[s]/week but below guideline), or 3) Inactive (zero MV sessions/week). A health-related utility score was derived from participant responses to the 12 item Short-Form Health Survey at baseline and two years later. QALY was calculated as the area under utility curve over two years. Relationship of physical activity level to median QALY adjusted for socioeconomic and health factors was estimated using quantile regression. Results Relative to the Inactive, median QALYs over two years were significantly higher for the Meeting Guidelines (0.112, 95% confidence interval [CI] 0.067–0.157) and Insufficiently Active (0.058, 95% CI 0.028–0.088) groups controlling for socioeconomic and health factors. Conclusion We found a significant graded relationship between greater physical activity level and higher QALYs. Using the more conservative estimate of 0.058, if an intervention could move someone out of the Inactive group and costs <$2900 over two years, it would be considered cost effective. Our analysis supports interventions to promote physical activity even if recommended levels are not fully attained.

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“…[12][13][14] These interventions can also be successfully implemented in a cost-effective way in primary care settings to reduce CVD risk and to improve quality of life. 131 Pedometer programs and mass media-based community campaigns have been found to be the most cost-effective, whereas general practitioner referral to an exercise physiologist was the least cost-effective because of travel costs and the associated time spent on consultation and screening. 127 A behavior-based intervention in which participants were taught to integrate daily moderately vigorous physical activity into their lives was found to be more cost-effective than a structured exercise program for improving physical activity and cardiovascular health.…”

Section: Physical Activitymentioning

confidence: 99%

Value of Primordial and Primary Prevention for Cardiovascular Disease

Weintraub¹,

Daniels²,

Burke³

et al. 2011

Circulation

455

265

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Abstract-The process of atherosclerosis may begin in youth and continue for decades, leading to both nonfatal and fatal cardiovascular events, including myocardial infarction, stroke, and sudden death. With primordial and primary prevention, cardiovascular disease is largely preventable. Clinical trial evidence has shown convincingly that pharmacological treatment of risk factors can prevent events. The data are less definitive but also highly suggestive that appropriate public policy and lifestyle interventions aimed at eliminating tobacco use, limiting salt consumption, encouraging physical exercise, and improving diet can prevent events. There has been concern about whether efforts aimed at primordial and primary prevention provide value (ie, whether such interventions are worth what we pay for them). Although questions about the value of therapeutics for acute disease may be addressed by cost-effectiveness analysis, the long time frames involved in evaluating preventive interventions make cost-effectiveness analysis difficult and necessarily flawed. Nonetheless, cost-effectiveness analyses reviewed in this policy statement largely suggest that public policy, community efforts, and pharmacological intervention are all likely to be cost-effective and often cost saving compared with common benchmarks. The high direct medical care and indirect costs of cardiovascular disease-approaching $450 billion a year in 2010 and projected to rise to over $1 trillion a year by 2030 -make this a critical medical and societal issue. Prevention of cardiovascular disease will also provide great value in developing a healthier, more productive society. (Circulation. 2011;124:967-990.)

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Quality of Life and Cost-effectiveness of a 3-Year Trial of Lifestyle Intervention in Primary Health Care

Abstract: Lifestyle intervention in primary care improves QOL and is highly cost-effective in relation to standard care. Trial Registration clinicaltrials.gov Identifier: NCT00486941.

Cited by 83 publications

References 31 publications

Comparative Study on Effect of Breathing and Aerobic Exercise on General Health in Asymptomatic Population

Comparative Study on Effect of Breathing and Aerobic Exercise on General Health in Asymptomatic Population

Relationship of meeting physical activity guidelines with quality-adjusted life-years

Value of Primordial and Primary Prevention for Cardiovascular Disease

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