Quality of life 9 years after an intensive care unit stay: A long-term outcome study

Stricker, Kay H.; Sailer, Susanne; Uehlinger, Dominik E.; Rothen, Hans Ulrich; Zenklusen, Regula M. Zuercher; Frick, Sonia

doi:10.1016/j.jcrc.2010.11.004

Cited by 14 publications

(7 citation statements)

References 38 publications

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“…The outcome of ICU treatment is mostly reported as mortality or report on a specific diagnostic group 37 , 38 . Ten years mortality after ICU discharge of our study was 63% and somewhat higher than found by Stricker after 9 years 33 . This may be due to the fact that Stricker included patients who were admitted longer than 24 h while we included only patients with an ICU stay longer than 48 h and therefore those patients were possibly sicker with a higher probability of death.…”

Section: Discussioncontrasting

confidence: 55%

Health-related quality of life in ICU survivors—10 years later

Hofhuis

Schrijvers

Schermer

et al. 2021

Sci Rep

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Many Intensive Care (ICU) survivors experience long lasting impairments in physical and psychological health as well as social functioning. The objective of our study was to evaluate these effects up to 10 years after ICU discharge. We performed a long-term prospective cohort study in patients admitted for longer than 48 h in a medical-surgical ICU. We evaluated health-related quality of life (HRQOL) before ICU admission using the Short-form-36 (SF-36), at ICU discharge, at hospital discharge and at 1, 2, 5 and 10 years follow up (all by patients). Changes in HRQOL were assessed based on linear mixed modeling. We included a total of 749 patients (from 2000 to 2008). During 10 years 475 (63.4%) patients had died, 125 (16.7%) patients were lost to follow up and 149 (19.9%) patients could be evaluated. The mean scores of four HRQOL dimensions (i.e., physical functioning (p < 0.001; mean 54, SD 32, effect size 0.77, 95% CI [0.54–1.0]), role-physical (p < 0.001; mean 44, SD 47, effect size 0.65, 95% CI [0.41–0.68] general health (p < 0.001; mean 52, SD 27, effect size 0.48; 95% CI 0.25–0.71) and social functioning (p < 0.001; mean 72, SD 32, effect size 0.41, 95% CI [0.19–0.64]) were still lower 10 years after ICU discharge compared with pre-admission levels (n = 149) and with an age reference population. Almost all SF-36 dimensions changed significantly over time from ICU discharge up to 10 years after ICU discharge. Over the 10 year follow up physical functioning of medical-surgical ICU survivors remains impaired compared with their pre-admission values and an age reference population. However, effect sizes showed no significant differences suggesting that surviving patients largely regained their age-specific HRQOL at 10 years.

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Section: Discussioncontrasting

confidence: 55%

Health-related quality of life in ICU survivors—10 years later

Hofhuis

Schrijvers

Schermer

et al. 2021

Sci Rep

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“…Survivors of critical illness may endure psychological and physical pathologies such as anxiety, depression, post‐traumatic stress disorder (PTSD), fatigue, polyneuromyopathy, reduced mobility, and shortness of breath and low HRQoL after hospital discharge (Stricker et al ., ; Kowalczyk et al ., ; Fumis et al ., ). As a consequence, patients often require both physical and psychological support during their rehabilitation (Needham et al ., ; Jones, ).…”

Section: Background: Problem Identificationmentioning

confidence: 99%

Outcomes and experiences of relatives of patients discharged home after critical illness: a systematic integrative review

Stayt

Venes

2018

Nursing in Critical Care

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Background Patients discharged from intensive care may experience psychological and physical deficits resulting in a long and complex rehabilitation upon discharge. Relatives are also vulnerable to psychological pathologies and diminished health‐related quality of life following the patients' critical illness. Relatives often provide care during the patients' rehabilitation, which may influence their health. Aim To report the outcomes and experiences of relatives of patients discharged home after critical illness. Design Systematic integrative review. Methods Electronic databases Cumulative Index of Nursing and Allied Health Literature, PubMed, Embase®, and PsychINFO® were searched using keywords, synonyms, and medical subject headings. Reference lists of articles and critical care journals were manually searched. Studies eligible for inclusion reported primary research and were published in English between 2007 and 2017. Studies were appraised using the Critical Appraisal Skills Programme checklists. Data were extracted and then analysed according to framework. Findings Twenty‐five studies were included: 19 quantitative, 4 qualitative, and 1 mixed method study. Three themes were identified: health and well‐being, employment and lifestyle, and caregiving role. Health and well‐being reports the incidence and significance of psychological morbidity such as post‐traumatic stress disorder, anxiety, and depression. Employment and lifestyle describes the impact of caregiving on the relative's ability to work and engage in usual social activities. The final theme describes and discusses the caregiving role in terms of activities of daily living, knowledge and skills, and adaption to the role. Conclusions There is a significant and meaningful impact on outcomes and experiences of relatives of patients discharged home after critical illness. Relatives' caregiving is embedded within the context of their psychological morbidity and social adjustment. Relevance to practice If informal care giving is to be sustainable, there is a need to design effective strategies of supporting families through all stages of the critical illness trajectory.

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“…(13,27,28) There are few papers on COPD patients with severe exacerbations who require ICU hospitalization (9,14) or that include COPD patients after ICU discharge. (3,5,8,10) Studies evaluating patients with chronic respiratory disease after ICU hospitalization are very important because they add information about the possible benefits of ICU admissions in these chronically ill patients.…”

Section: Discussionmentioning

confidence: 99%

Chronic obstructive pulmonary disease exacerbation in the intensive care unit: clinical, functional and quality of life at discharge and 3 months of follow up

Viana¹,

Pincelli²,

Pizzichini³

et al. 2017

Revista Brasileira De Terapia Intensiva

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ObjectiveThe purpose of this study was to evaluate the clinical/functional aspects and quality of life of chronic obstructive pulmonary disease patients who were discharged after an intensive care unit admission for acute respiratory failure.MethodsThis prospective study included chronic obstructive pulmonary disease patients who were admitted to two intensive care units between December of 2010 and August of 2011 and evaluated over three visits after discharge. Thirty patients were included, and 20 patients completed the three-month follow up.ResultsThere was a significant improvement in the following: forced expiratory flow in one second (L) (1.1/1.4/1.4; p = 0.019), six-minute walk test (m) (- /232.8 /272.6; p = 0.04), BODE score (7.5/5.0/3.8; p = 0.001), cognition measured by the Mini Mental State Examination (21/23.5/23.5; p = 0.008) and quality of life measured by the total Saint George Respiratory Questionnaire score (63.3/56.8/51, p = 0.02). The mean difference in the total score was 12.3 (between visits 1 and three). Important clinical differences were observed for the symptom score (18.8), activities score (5.2) and impact score (14.3). The majority of participants (80%) reported they would be willing to undergo a new intensive care unit admission.ConclusionDespite the disease severity, there was a significant clinical, functional and quality of life improvement at the end of the third month. Most patients would be willing to undergo a new intensive care unit admission.

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Quality of life 9 years after an intensive care unit stay: A long-term outcome study

Cited by 14 publications

References 38 publications

Health-related quality of life in ICU survivors—10 years later

Health-related quality of life in ICU survivors—10 years later

Outcomes and experiences of relatives of patients discharged home after critical illness: a systematic integrative review

Chronic obstructive pulmonary disease exacerbation in the intensive care unit: clinical, functional and quality of life at discharge and 3 months of follow up

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