Quality Evaluation of Polar and Active Components in Crude and Processed<i>Fructus Corni</i>by Quantitative Analysis of Multicomponents with Single Marker

Jiang, Yuhong; Chen, Hui; Wang, Liling; Zou, Jingxiang; Zheng, Xiao; Liu, Zhihui

doi:10.1155/2016/6496840

Cited by 19 publications

(15 citation statements)

References 11 publications

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“…Secoiridoids are believed to be even more advanced due to the more complicated biostynthetic steps (Xiang et al, 1996). Thus, the most closely related in the iridoids transformation pathway compounds, such as loganin ( 1 ), loganic acid ( 3 ), cornin ( 4 ), sweroside ( 5 ), and representative of secoiridoids, cornuside ( 6 ), have been detected both in fruits of C. mas and C. officinalis (Deng et al, 2013; Ma et al, 2014; Perova et al, 2014; Sochor et al, 2014; Kucharska et al, 2015; Jiang et al, 2016). However, it should be noted that in the 26 cultivars of C. mas it was shown that the most abundant iridoid was loganic acid ( 3 ) (81.5–461.1 mg/100 g fw) constituting 88–96% of total iridoids (86.9–493.7 mg/100 g fw).…”

Section: Similarities and Differences In The Chemical Composition Of mentioning

confidence: 99%

Cornus mas and Cornus Officinalis—Analogies and Differences of Two Medicinal Plants Traditionally Used

Czerwińska

Melzig

2018

Front. Pharmacol.

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Among 65 species belonging to the genus Cornus only two, Cornus mas L. and Cornus officinalis Sieb. et Zucc. (Cornaceae), have been traditionally used since ancient times. Cornus mas (cornelian cherry) is native to southern Europe and southwest Asia, whereas C. officinalis (Asiatic dogwood, cornel dogwood) is a deciduous tree distributed in eastern Asia, mainly in China, as well as Korea and Japan. Based on the different geographic distribution of the closely related species but clearly distinct taxa, the ethnopharmacological use of C. mas and C. officinalis seems to be independently originated. Many reports on the quality of C. mas fruits were performed due to their value as edible fruits, and few reports compared their physicochemical properties with other edible fruits. However, the detailed phytochemical profiles of C. mas and C. officinalis, in particular fruits, have never been compared. The aim of this review was highlighting the similarities and differences of phytochemicals found in fruits of C. mas and C. officinalis in relation to their biological effects as well as compare the therapeutic use of fruits from both traditional species. The fruits of C. mas and C. officinalis are characterized by the presence of secondary metabolites, in particular iridoids, anthocyanins, phenolic acids and flavonoids. However, much more not widely known iridoids, such as morroniside, as well as tannins were detected particularly in fruits of C. officinalis. The referred studies of biological activity of both species indicate their antidiabetic and hepatoprotective properties. Based on the available reports antihyperlipidemic and anticoagulant activity seems to be unique for extracts of C. mas fruits, whereas antiosteoporotic and immunomodulatory activities were assigned to preparations of C. officinalis fruits. In conclusion, the comparison of phytochemical composition of fruits from both species revealed a wide range of similarities as well as some constituents unique for cornelian cherry or Asiatic dogwood. Thus, these phytochemicals are considered the important factor determining the biological activity and justifying the use of C. mas and C. officinalis in the traditional European and Asiatic medicine.

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Section: Similarities and Differences In The Chemical Composition Of mentioning

confidence: 99%

Cornus mas and Cornus Officinalis—Analogies and Differences of Two Medicinal Plants Traditionally Used

Czerwińska

Melzig

2018

Front. Pharmacol.

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“…The relative correction factor for component I (internal standard) is the ratio of the absolute correction factor for component I to standard substance S (reference compound). In previous studies, loganin has also been used as the internal standard to calculate different components of Fructus corni (Jiang et al, ). Several studies on relative correction factors are available (Dou et al, ; He et al, ; He, Liu, Tian, Li, & Yang, ; Huang, Yang, Shi, Wang, & Wang, ; Kong, Zhu, Wang, Zhang, & Feng, ).…”

Section: Resultsmentioning

confidence: 99%

“…In previous studies of QAMS, researchers have investigated the stability of different columns and instruments (Wang, Zhang, Sun, & Chen, ). Other studies have investigated the reproducibility of the relative correction factors of different instruments and columns (Li et al, ; Zhu et al, ), and different column temperatures and flow rates (Jiang et al, ). In this study, the stability of the relative correction factors of different column temperatures (25, 30 and 30°C), two brands of columns (namely, Waters Acquity BEH C 18 , 100 × 2.1 mm, 1.7 μm and Thermo Syncronis C 18 , 100 × 2.1 mm, 1.7 μm) and three assistants were investigated.…”

Section: Resultsmentioning

confidence: 99%

Quality evaluation for Radix Astragali based on fingerprint, indicative components selection and QAMS

Huang

Yin²,

Dong

et al. 2018

Biomedical Chromatography

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Radix Astragali (RA) is one of the most widely used Chinese herbs prescribed in many Chinese formulas to reinforce 'Qi' and treat vital energy deficiency. This study combined fingerprinting with quantitative analysis multi-components by a single marker (QAMS) to improve the quality control standard for RA on the basis of existing quality control methods of traditional Chinese medicinal materials. UPLC-ESI-TOF-MS technique was used to evaluate the quality of RA by fingerprinting and QAMS. Using the anti-inflammatory, anti-oxidation and anti-anoxic activities to screen characteristic components of RA, the calycosin-7-O-β-d-glucoside (CG), ononin, astragaloside IV, astragaloside II, calycosin and astrageloside I significantly inhibited ear edema in mice, the calycosin and CG had good antioxidant activity and the astragaloside I had a significant anti-hypoxia activity. Astragaloside I, astragaloside II, astragaloside IV, ononin, calycosin and CG had significant pharmacological actions. These components were comprehensively used as the indicative components for the quality control of RA. Astragaloside I was used as the internal standard of the relative correction factors of CG (13.45), ononin (0.51), calycosin (12.08), astragaloside IV (0.73) and astragaloside II (0.81). Astragaloside I and CG were used as internal standards of the relative correction factors of the flavonoids and saponins of ononin (1.11), calycosin (0.04), astragaloside IV (0.73) and astragaloside II (0.81). The study combined fingerprinting with QAMS to improve the quality control standard for RA.

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“…Three components have clear chemical structure, obvious pharmaceutical properties, and convenient detection, so they should be considered for study first. QAMS, which has many advantages such as low cost and high efficiency, has been widely used in the determination of traditional Chinese medicine and multi-index components in recent years [ 17 , 22 – 26 ]. In this experiment, the 3 components to be tested were curcumin derivatives and curcumin was a representative component of these compounds and is easy to obtain.…”

Section: Discussionmentioning

confidence: 99%

Study on Quality Standard of Processed Curcuma Longa Radix

Chen

Zhao

Quan

et al. 2017

Evidence-Based Complementary and Alternative Medicine

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To control the quality of Curcuma Longa Radix by establishing quality standards, this paper increased the contents of extract and volatile oil determination. Meanwhile, the curcumin was selected as the internal marker, and the relative correlation factors (RCFs) of demethoxycurcumin and bisdemethoxycurcumin were established by high performance liquid chromatography (HPLC). The contents of multicomponents were calculated based on their RCFs. The rationality and feasibility of the methods were evaluated by comparison of the quantitative results between external standard method (ESM) and quantitative analysis of multicomponents by single-marker (QAMS). Ethanol extracts ranged from 9.749 to 15.644% and the mean value was 13.473%. The volatile oil ranged from 0.45 to 0.90 mL/100 g and the mean value was 0.66 mL/100 g. This method was accurate and feasible and could provide a reference for further comprehensive and effective control of the quality standard of Curcuma Longa Radix and its processed products.

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Quality Evaluation of Polar and Active Components in Crude and ProcessedFructus Corniby Quantitative Analysis of Multicomponents with Single Marker

Cited by 19 publications

References 11 publications

Cornus mas and Cornus Officinalis—Analogies and Differences of Two Medicinal Plants Traditionally Used

Cornus mas and Cornus Officinalis—Analogies and Differences of Two Medicinal Plants Traditionally Used

Quality evaluation for Radix Astragali based on fingerprint, indicative components selection and QAMS

Study on Quality Standard of Processed Curcuma Longa Radix

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