Abstract:Aim: Hormone responsive breast cancer is the most prevalent cancer worldwide. Letrozole is a third-generation aromatase inhibitor widely used for the treatment of advanced breast cancer. The primary objective of the present work is to develop and optimize an injectable solid lipid nanoparticle incorporating letrozole to circumvent the side-effects of a marketed conventional formulation and thereby improve patient compliance. Materials and Methods: Emulsification solvent evaporation and melt dispersion techniqu… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.