Quality by design‐based optimization of formulation and process parameters for berberine nanosuspension for enhancing its dissolution rate, bioavailability, and cardioprotective activity
Abstract:Berberine (BER) is a natural alkaloid that is extracted from the root and bark of Berberis aristata (family Berberidaceae). It is commonly known as "Daru haldi" in Urdu. In traditional Chinese medicine and Ayurveda, BER formulations are widely used to treat illnesses like hypertension, and inflammatory conditions. BER has also been extensively explored for many pharmacological activities such as anti-arrhythmic, antimalarial, anticancer, anti-hyperglycemic, antioxidant, hepatoprotective, and antimicrobial acti… Show more
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