Qualitative and quantitative analysis of Radix Astragali products by fast high-performance liquid chromatography-diode array detection coupled with time-of-flight mass spectrometry through dynamic adjustment of fragmentor voltage

The advantages of using traditional Chinese medicine as an adjunctive therapy in the whole course of cancer treatment instead of only terminal stage of cancer

“…mongholicus, and one of the most famous and frequently used herbal medicines and healthy food supplements used as a tonic. It has been used for over 2000 years in TCM prescriptions for the treatment of animal bites and poisons, wounds and burns, nephritis, diabetes, albuminuria, hypertension, cirrhosis, and various cancers (24). Chemical constituent investigations on Radix Astragali indicated that it contains several bioactive constituents including, isoflavonoids, triterpenoid saponins, polysaccharides, amino butyric acids and various trace elements; of which triterpenoid saponins represent the major beneficial constituents responsible for the bioactivities and efficacies of Radix Astragali on human health (25).…”

Study of the Relationship between Genetics and Geography in Determining the Quality of Astragali Radix

“…In the case of AR, scientific data has confirmed that AR from Hunyuan, Shanxi Province does have the highest total concentration of active isoflavonoids and saponins when compared with drugs from other regions. 12,13) Phytochemical studies have shown that the main active components in medicinal plants are secondary metabolites which are produced during the growth and development of plants as they adapt to the environment. 14) These components are usually used as markers for identification and quality evaluation of TCMs.…”

Biopesticides from Natural Products: Current Development, Legislative Framework, and Future Trends

“…However, purification of these fractions requires more selective and environmentally friendly extraction techniques, such as supercritical fluid extraction using carbon dioxide, which is a widely used and sustainable process (Santos et al 2012). The organic fraction is collected, concentrated, and fractionated or purified using column chromatography, and active substances can be identified and quantified on chromatographic systems coupled to detection systems such as mass spectrometry (Qi et al 2008;Jalali et al 2012), or nuclear magnetic resonance techniques when the active substance is isolated in a very pure form (Asili et al 2009). …”