Quadrivalent Human Papillomavirus Vaccine: Recommendations of the Advisory Committee on Immunization Practices (ACIP)

Markowitz, Lauri E.; Dunne, Eileen F.; Saraiya, Mona; Lawson, Herschel W.; Chesson, Harrell W.; Unger, Elizabeth R.

doi:10.1037/e601292007-001

Cited by 1,317 publications

(1,764 citation statements)

References 98 publications

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“…Recently, HPV vaccines have been devised to provide protection against HPV gene products. Some of these have shown promise as immunotherapies for HPV-associated cancers [37][38][39].…”

Section: Discussionmentioning

confidence: 99%

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Papillomas of the External Ear Canal: Report of Ten cases in Chinese Patients with HPV In Situ Hybridization

Wang

Yee

Wen

et al. 2009

Head and Neck Pathol

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Squamous papilloma is a benign exophytic proliferation which can occur occasionally in the external ear canal. It is widely assumed that the Human Papilloma Virus (HPV) is an etiologic factor of papillomas. Available techniques for detection of HPV genomes include immunohistochemistry, Southern blot hybridization, in situ hybridization (ISH), and polymerase chain reaction. To our knowledge, HPV typing has not been reported on tissue sections of papillomas in the external ear canal. We report HPV ISH analysis in ten cases of papillomas, involving the external ear canal in Chinese patients. These papilloma excrescences were less than 1 cm in diameter, and were benign morphologically. Automated HPV ISH analysis was performed for the hybridization of DNA probes, including both low-risk and high-risk HPV subtypes. HPV ISH results revealed that seven out of ten cases were positive for low-risk HPV (6, 11), three cases demonstrated no hybridization for low-risk HPV probe, and none of the cases revealed any detection of high-risk HPV (16, 18, 31, 33, 35, 39, 51, 52, 56, 58, and 66). On follow-up after 18-29 months (average 24.5 months), eight patients were doing well, with no local recurrence after excision. Two patients were lost to follow-up. Our results confirm that benign papillomas of the external ear canal are associated with low-risk HPV infection with benign behavior and neither recurrence nor high grade dysplasia.

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“…Recently, HPV vaccines have been devised to provide protection against HPV gene products. Some of these have shown promise as immunotherapies for HPV-associated cancers [37][38][39].…”

Section: Discussionmentioning

confidence: 99%

“…The low risk group DNA probe contains HPV genotypes 6 and 11, while the high risk HPV group contains HPV genotypes 16,18,31,33,35,39, 51, 52, 56, 58, and 66. Positive and negative controls were hybridized alongside the study cases.…”

Section: Methodsmentioning

confidence: 99%

Papillomas of the External Ear Canal: Report of Ten cases in Chinese Patients with HPV In Situ Hybridization

Wang

Yee

Wen

et al. 2009

Head and Neck Pathol

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“…Several HPV vaccines have been developed, including a bivalent (strains 16 and 18) and a quadrivalent (strains 16, 18, 6, and 11) vaccine (Harper et al, 2004;Villa et al, 2005;Harper et al, 2006). The Centers for Disease Control and Prevention's Advisory Committee on Immunization Practices (ACIP) recommends routine vaccination of girls aged 11-12 years, as well as for those aged 13-26 years who have not been previously vaccinated (Markowitz et al, 2007;Vadaparampil et al, 2011). A quadrivalent vaccine was licensed by the US Food and Drug Administration (FDA) for use in males 9 through 26 years of age in 2009 (American Academy of Pediatrics, 2012).…”

Section: Knowledge and Attitudes About Human Papillomaviruses And Immmentioning

confidence: 99%

Knowledge and Attitudes about Human Papillomaviruses and Immunization among Turkish Pediatricians

Özsürekçi

Öncel²,

Bayhan³

et al. 2013

Asian Pacific Journal of Cancer Prevention

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“…Fortunately more than 80% of HPV infections are removed over a 3-4 years without any intervention; on the other hand primary prevention trough vaccination and screening for cervical cancer seems to be effective (Wong, 2009). HPV vaccine is safe and reduces development of cervical cancer up to 70% (Medeiros, 2005;Zhao et al, 2012) which should be administered before or shortly after sexual contact to have optimal effectiveness (Markowitz et al, 2007;Pollack …”

Section: Introductionmentioning

confidence: 99%

Knowledge and Attitude of Iranian University Students toward Human Papilloma Virus

Ghojazadeh

Azar²,

Saleh³

et al. 2012

Asian Pacific Journal of Cancer Prevention

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Introduction: Increasing prevalence of human papilloma virus (HPV) infection and its association with cervical cancer as a leading cause of death make it necessary to evaluate and improve the public knowledge, especially of university students, about this cause of disease. Methods: A cross-sectional study of knowledge and attitude of a total 669 students from Tabriz University of Medical Sciences was therefore performed with a modified validated questionnaire, arranged into 5 parts and containing 55 questions, in July 2011. Questions were directed to study socio-demographic characteristics of the participant, knowledge about HPV disease, transmission route, relationship with cervical cancer, predisposing factors, and participants attitude toward people with HPV infection. Results: All of the participants were Moslem with a mean age 25.6±5.33 years of age. All of the participants had heard of HPV, and acquired their knowledge through university courses (90.6%); the majority of them knew that HPV is a sexually transmitted disease and a potential cause for genital warts but general knowledge about details was not high. Mean knowledge score of residents and post graduate midwifery and nursing students was high as compared to other groups (P<0.001). Statements that indicated the presence of fear to communicate with people suffering HPV and people's avoidance to rely on babysitting of these patients were observed. Educational level (β=0.21, P<0.001), age (β=0.18, P=0.002,) and smoking (β=-0.11, P=0.006) were predicted to effect knowledge. Conclusions: Moderate level of knowledge about HPV among medical university students makes it necessary to set effective national public health efforts on HPV education and prevention considering he excess of young population in Iran vulnerable to cervical cancer.

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Quadrivalent Human Papillomavirus Vaccine: Recommendations of the Advisory Committee on Immunization Practices (ACIP)

Cited by 1,317 publications

References 98 publications

Papillomas of the External Ear Canal: Report of Ten cases in Chinese Patients with HPV In Situ Hybridization

Papillomas of the External Ear Canal: Report of Ten cases in Chinese Patients with HPV In Situ Hybridization

Knowledge and Attitudes about Human Papillomaviruses and Immunization among Turkish Pediatricians

Knowledge and Attitude of Iranian University Students toward Human Papilloma Virus

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