Quadriceps echo intensity can be an index of muscle size regardless of age in 65 or more years old

Akima, Hiroshi; Yoshiko, Akito; Ogawa, Madoka; Maeda, Hisashi; Tomita, Aya; Ando, R.; Tanaka, Noriko

doi:10.1016/j.exger.2020.111015

Cited by 16 publications

(21 citation statements)

References 39 publications

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“…In agreement with our observations, Akima et al 28 observed that the quadriceps muscle thickness was negatively associated with muscle echo intensity ( r = −0.438 to −0.736) in older males and females. Similarly, several others have observed negative associations between muscle echo intensity and muscle thickness in older adults 27,31,33 . However, negative associations between muscle thickness and echo intensity in older adults are not always observed ( r = −0.10) 14 .…”

Section: Discussionmentioning

confidence: 67%

“…Similarly, several others have observed negative associations between muscle echo intensity and muscle thickness in older adults. 27,31,33 However, negative associations between muscle thickness and echo intensity in older adults are not always observed (r = À0.10). 14 Interestingly, Chang et al 34 observed a moderate negative association between rectus femoris muscle thickness and echo intensity (r = À0.48) in 140 community-dwelling older adults, but weak associations for the biceps (r = À0.18), triceps (r = À0.07), and the gastrocnemius (r = À0.20) muscles.…”

Section: Discussionmentioning

confidence: 99%

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Influence of Subcutaneous Adipose Tissue and Skeletal Muscle Thickness on Rectus Femoris Echo Intensity in Younger and Older Males and Females

Paris

Bell

Avrutin

et al. 2021

J of Ultrasound Medicine

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Objectives-Ultrasound measurements of muscle echo intensity are commonly used surrogates of muscle composition (eg, intramuscular adipose tissue). However, given that soundwaves are increasingly attenuated with tissue depth, the interpretation of echo intensity may be confounded by adipose and skeletal muscle thickness. Our objectives are to compare the associations between adipose or muscle tissue thickness and rectus femoris echo intensity in younger and older males and females.Methods-Participants included in this analysis were derived from 3 previously published cohorts of younger (<45 years) and older (≥60 years) males and females. Ultrasound images of the rectus femoris were evaluated for muscle thickness, echo intensity, and subcutaneous adipose tissue thickness.Results-Older adults (n: 49 males, 19 females) had a higher body mass index (P = .001) compared with younger adults (n: 37 males, 49 females). Muscle thickness was negatively associated with echo intensity in older males (r = À0.59) and females (r = À0.53), whereas no associations were observed in younger males (r = 0.00) or females (r = À0.11). Subcutaneous adipose tissue thickness displayed no associations with echo intensity in any group.Conclusions-Despite the known influence of subcutaneous adipose tissue thickness on beam attenuation, we observed no association with muscle echo intensity, indicating that adipose tissue correction may be required to better understand muscle echo intensity across differences in adiposity. The negative associations between muscle thickness and echo intensity in older, but not younger adults, suggests these associations may be related to the co-occurrence of skeletal muscle atrophy and intramuscular adipose tissue infiltration with advancing age.

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Section: Discussionmentioning

confidence: 67%

Section: Discussionmentioning

confidence: 99%

Influence of Subcutaneous Adipose Tissue and Skeletal Muscle Thickness on Rectus Femoris Echo Intensity in Younger and Older Males and Females

Paris

Bell

Avrutin

et al. 2021

J of Ultrasound Medicine

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“…Forward stepwise multiple regression analysis was performed using variables that made a significant contribution to the variance (input criteria, P ≤ 0.05 and output criteria, P ≤ 0.100 were the default software settings). The dependent variable was the %IntraMAT of the trunk muscles and the independent variables were age, BMI, %body fat, abdominal circumference, diastolic blood pressure, systolic blood pressure, alcohol consumption category, smoking category, VAT and SCAT CSAs, and muscle tissue CSA and frequency of exercise (all groups analysis only), on the basis of the findings of our previous studies [ 18 , 20 , 32 ] and the results of simple correlation analyses. To avoid multicollinearity in the analysis, we checked that the variance inflation factor was lower than the set criterion of 10 in all the stepwise regression analyses.…”

Section: Methodsmentioning

confidence: 99%

Skeletal muscle and abdominal circumference explain intramuscular fat, independent of exercise frequency, in middle-aged Japanese men

et al. 2022

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The purpose of this study was to examine how intramuscular adipose tissue (IntraMAT) can be characterized using physical and functional characteristics, muscle size, and/or adipose tissue in four different exercise frequency groups of middle-aged Japanese men. One thousand twenty-eight middle-aged men (age, 47.5 ± 8.1 years; height, 170.5 ± 5.8 cm; body mass, 67.0 ± 9.3 kg; body mass index, 21.9 ± 5.3 kg/m2) were allocated to four groups on the basis of their weekly exercise frequency: Group 1, no exercise, n = 334; Group 2, once a week, n = 271; Group 3, a few days a week, n = 269; and Group 4, every day, n = 154. Their body composition, blood pressure, and handgrip strength were assessed. A single-slice computerized tomography image at the level of the umbilicus was acquired and the CSAs of IntraMAT, muscle tissue, and subcutaneous and visceral adipose tissues (SCAT and VAT) were calculated. The %IntraMAT significantly correlated with physical characteristics, such as age, BMI, abdominal circumference, and muscle tissue CSA. Stepwise multiple regression analysis was performed, with the %IntraMAT as the dependent variable. Muscle tissue CSA and abdominal circumference were the common independent variables across groups to explain the variability of the %IntraMAT. It was also extracted %body fat and age for Group 2, age, handgrip strength, and BMI for Group 3, and smoking category for Group 4. These results suggested that muscle tissue size and abdominal circumference would be the strong predictors to explain %IntraMAT of the trunk muscle across four groups, and that age, %body fat, BMI, and SCAT, handgrip strength and smoking category were also good predictors for each group with different exercise frequency in middle-aged Japanese men.

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“…The exercises selected involve muscle groups (e.g. quadriceps femoris) with higher age-related loss ( Abe et al, 2014 ; Janssen et al, 2000 ; Lynch et al, 1999 ), which are associated to functional capacity in older individuals ( Akima et al, 2020 ; Byrne et al, 2016 ; Misic et al, 2007 ; Suzuki et al, 2001 ; Wilhelm et al, 2014 ). Moreover, a sequence of progression of squat exercise is shown in Fig.…”

Section: Home-based Resistance Training As a Strategy To Avoid A Harmmentioning

confidence: 99%

COVID-19 pandemic is an urgent time for older people to practice resistance exercise at home

Machado

Pinto

Brusco

et al. 2020

Experimental Gerontology

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Social distancing measures have been used to contain the COVID-19 pandemic; nevertheless, it causes unintended greater time at home and consequently a reduction in general physical activity and an increase in sedentary time, which is harmful to older people. A decrease in daily physical activities and an increase in sedentary time culminates in an impactful skeletal muscle disuse period and reduction in neuromuscular abilities related to functional capacity. Home-based resistance training is a strategy to mitigate physical inactivity and improve or retain muscle function and functional performance. Therefore, it is an urgent time to encourage older people to perform resistance exercises at home to avoid a harmful functional decline and promote physical health.

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Quadriceps echo intensity can be an index of muscle size regardless of age in 65 or more years old

Cited by 16 publications

References 39 publications

Influence of Subcutaneous Adipose Tissue and Skeletal Muscle Thickness on Rectus Femoris Echo Intensity in Younger and Older Males and Females

Influence of Subcutaneous Adipose Tissue and Skeletal Muscle Thickness on Rectus Femoris Echo Intensity in Younger and Older Males and Females

Skeletal muscle and abdominal circumference explain intramuscular fat, independent of exercise frequency, in middle-aged Japanese men

COVID-19 pandemic is an urgent time for older people to practice resistance exercise at home

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