Qiju Dihuang Decoction for Hypertension: A Systematic Review and Meta‐Analysis

Abstract

Objective. To systematically evaluate the efficacy of Chinese herbal medicine Qiju Dihuang Decoction (QDD) for hypertension. Methods. A comprehensive literature search of randomized controlled trials using QDD to treat hypertension was conducted in 7 electronic databases, including Chinese databases. Subjects and abstracts of the trials were read in NoteExpress for preliminary screening, and the full text was read for further screening. The data extraction table was made for the selected 19 trials, and risk of bias was assessed by using the Cochrane collaboration tool, followed by data analysis using Rev Man 5.3. Results. The antihypertensive efficacy of QDD is 1.45 times that of antihypertensive drugs and 1.56 times that of conventional therapies, which can also reduce the endothelin level. QPAD exhibits an antihypertensive effect, and its clinical efficacy is 1.34 times and 1.61 times that of antihypertensive drugs, which can not only significantly lower the diastolic blood pressure but also reduce the 24 h mean ambulate blood pressure. At the same time, it can decrease the TCM syndrome score, inhibit the inflammation, protect the renal function, reduce the insulin resistance, and improve the life quality of patients. Conclusion. QDD can effectively reduce blood pressure and improve the life quality of patients with hypertension, which plays a certain role in preventing hypertension complications. However, due to the methodological deficiencies, more rigorous randomized controlled trials will be needed in the future to provide stronger evidence.

An Epidemiological Study on the Relationship between Drug Control Program and Patient Compliance in Elderly Patients with Hypertension

“…(2) Qiju Dihuang Decoction has the functions of clearing liver and cooling blood, reducing fire and diuresis, and clearing heat, inducing heat and reducing heat pressure effect. After taking the medicine, it can quickly relieve the problem of high blood pressure and treat constipation, dizziness, and other adverse conditions [33]; (3) Erxian Decoction can also be used to treat hypertension in the elderly. e function of conditioning Chong and Ren to lower blood pressure is quite significant [34].…”

PROTOCOL: Home‐based care for people with dementia: A systematic review

“…Subgroup analysis will be conducted to examine the effects of varying interventions and populations, as well as the heterogeneity of included studies. In case a quantitative synthesis is not possible, study findings will be synthesized narratively (Campbell, 2020; Yang, 2018). The data (e.g., events, sample size, and point estimates) will be presented with forest plot or table and grouped by different outcomes and comparisons.…”

Efficacy of felodipine and enalapril in the treatment of essential hypertension with coronary artery disease and the effect on levels of Salusin-β, Apelin, and PON1 gene expression in patients

“…Some studies have reported that vascular endothelial cell damage and local inflammatory responses have a greater relationship with the development of hyperemia and coronary heart disease (28), which can increase vascular tension and exacerbate thrombosis, among which Sa-lusin-β can promote the release of inflammatory factors in the body and aggravate the degree of damage to vascular endothelial cells, which in turn induces coronary heart disease and is expected to become an important marker for predicting the development of coronary heart disease. Serum Apelin has diuretic, vasodilating and vascular regenerative effects, and is a protective factor in coronary artery disease.…”