Q-switched ruby laser therapy of nevus of Ota

Long- and Short-term Histological Observations of Congenital Nevi Treated With the Normal-Mode Ruby Laser

“…The Q-switched ruby laser could selectively damage such pigmentation, as previously reported for oculodermal melanosis and tattoos. 5,6,8 In our short-term studies in 3 patients, the pigmented cells in the epidermis showed considerable thermal damage following each laser treatment. Therefore, the nests of pigmented nevus cells seen in the epidermis of the poorly responsive lesions presumably represent the regeneration of nevus cells that contained little melanin and were thus spared from thermal damage.…”

“…The evaluation procedure used was previously described. 8 Results were classified on a 5-point scale regarding the clearing of pigmentation (excellent, good, fair, poor, or no change) ( Table 1). In patients with a successful outcome, the treated areas of the congenital nevi were free of scarring, and their appearance and texture resembled that of the surrounding normal skin (Figure 1, A).…”

“…In addition, the Qswitched ruby laser was used in 3 patients to eradicate the bluish color that persisted even after the deep pigmentation had been reduced by use of the normal-mode ruby laser (patients [6][7][8]. The variables used for the Q-switched ruby laser were the same as those used for the test irradiation.…”

Laser Treatment of Pigmented Lesions-2000

“…The Q-switched ruby (694 nm), Q-switched alexandrite (755 nm), and Q-switched Nd:YAG (1064 nm) lasers are all highly effective in targeting the dendritic melanocytic cells in the dermis, producing significant (Ͼ75%) or complete lesional clearing after an average of 4 to 6 laser treatments with fluences ranging from 5 to 12 J/cm 2 . [33][34][35][36] The degree of lightening is usually directly proportional to the number of treatments performed. In a recent study by Ueda et al, 37 the number of treatments using a Q-switched ruby laser at low fluences (5 J/cm 2 ) was shown to depend on the color of the lesions, with the brown and violet lesions achieving optimal clearing after 3 to 4 laser treatments, in contrast to the more heavily pigmented blue-green nevi, which required 6 treatments for the same degree of lightening.…”

Q-Switched Nd:YAG Laser Therapy of Acquired Bilateral Nevus of Ota-like Macules

“…Based on the principles of selective photothermolysis, nevus of Ota has been successfully treated with Q-switched ruby lasers 4,5 , Q-switched alexandrite lasers 6 , and Q-switched Nd:YAG lasers (QSNYL) 7 . The histological similarities between ABNOM and nevus of Ota suggested that laser therapy may also be successful in the treatment of ABNOM.…”