“…Many published results express gross overestimates of cholecystokinin concentrations and provide little confidence that estimates actually relate to true concentrations of one or more of the many molecular forms of the peptide. One attempt to overcome such difficulties is to develop an antiserum to the amino-terminal region of the cholecystokinin octapeptide which does not cross-react with gastrins (Adrian et al 1983). This provides the possibility of direct estimation of cholecystokinin octapeptide without subtracting gastrin immunoreactivity.…”
“…Many published results express gross overestimates of cholecystokinin concentrations and provide little confidence that estimates actually relate to true concentrations of one or more of the many molecular forms of the peptide. One attempt to overcome such difficulties is to develop an antiserum to the amino-terminal region of the cholecystokinin octapeptide which does not cross-react with gastrins (Adrian et al 1983). This provides the possibility of direct estimation of cholecystokinin octapeptide without subtracting gastrin immunoreactivity.…”
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