Pyridine-containing block copolymeric nano-assemblies obtained through complementary hydrogen-bonding directed polymerization-induced self-assembly in water

Abstract

Pyridine-containing block copolymers are a special type of macromolecules, and they can self-assemble into highly-ordered nano-objects for a wide range of applications due to their multiple properties including the hydrogen...

ROPISA of salicylic acidO-carboxyanhydride: fast polymerization followed byin situkinetics-driven self-assembly

“…Solvophobicity is a key driving force for PISA, but other forces such as hydrogen bonding, electrostatic interactions, and crystallization can also contribute to the process. 17–19…”

Polyacrylamide-Based Block Copolymer Bearing Pyridine Groups Shows Unexpected Salt-Induced LCST Behavior

“…In order to demonstrate the key role of hydrogen-bonding interactions between the pyridine and amides in the temperature response of the Px, varying amounts of urea—which is commonly utilized to disturb hydrogen bonds—were added into the solution [ 36 ]. It was observed that with increases in urea concentrations from 0 to 7 M, the CPT of the P2 (1 mg/mL, 500 mM NaCl) significantly increased from ca.…”

“…After 3 cycles of freezing and thawing, the reaction was kept at 70 °C for 24 h to ensure that conversion approached 100%. MPA and PEG-CTA were synthesized according to our previous work [ 36 ].…”

Oxidation-responsive polymer vesicles with order–disorder–order multiple-phase transitions

“…Yang and Hua et al reported a new RIPT system that is driven by hydrogen bonding. 34 They found that the hydrophilic poly(ethylene glycol)- b -poly[ N -(2-methyl pyridine) acrylamide] (PEG- b -PMPA) copolymer could self-assemble in water via PISA, driven by the hydrogen bonding between pyridine and amide groups. Owing to the hydrogen bonding, these assemblies manifested thermo- and pH-responsiveness, which provides a new avenue for the design of stimuli-responsive polymer assemblies.…”