Oxidation-responsive polymer vesicles with order–disorder–order multiple-phase transitions

Abstract

Reaction-induced phase transition (RIPT) is an emerging strategy that allows the self-assembly of polymers and the regulation of nanoparticle morphology by in-situ chemical reactions. Despite the great potential, the driving...

Polymerization-induced self-assembly for the construction of nanostructured hydrogels

“…[29][30][31][32][33][34] Since its emergence, PISA has attracted intensive attention and has become the focus of polymer self-assembly. To date, various reversible deactivation radical polymerization techniques have been exploited in PISA, 35,36 including reversible addition-fragmentation chain-transfer radical polymerization (RAFT), [37][38][39] atom transfer radical polymerization (ATRP), 40,41 nitroxide mediated radical polymerization (NMP), 42,43 ringopening metathesis polymerization (ROMP), 44,45 and ringopening polymerization (ROP). [46][47][48] The monomer/solvent toolkit of PISA has also been greatly enlarged.…”

Oxidation-Responsive Polymeric Fluorinated Nanoparticles Prepared by Polymerization-Induced Self-Assembly

“…This transition from hydrophobic thioether to hydrophilic sulfoxide of MTEMA can lead to disassembly of polymeric nanoparticles. Similar thioether-based PISA systems have also been explored by Brendel, , Battaglia, Couturaud, and Huo to construct oxidation-responsive polymeric nanoparticles with potential applications in targeted drug delivery. Despite this progress, few of these PISA nanoparticles are capable of reporting oxidative conditions and the following oxidation-induced responsive behavior, which is a demanded feature in many biological applications …”