Pyostomatitis vegetans. Report of two cases and review of the literature

Ruiz-Roca, Juan Antonio; Berini-Aytés, Leonardo; Gay‐Escoda, Cosme

doi:10.1016/j.tripleo.2003.08.022

Cited by 54 publications

(33 citation statements)

References 14 publications

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“…Additionally, PD-PSV associated with liver dysfunction or primary sclerosing cholangitis were reported [2,8] . Our patient developed primary sclerosing cholangitis and UC prior to developing PD-PSV.Various treatments for PD-PSV have been reported [2,3] . Since PD-PSV reflects high disease activity, treatment of the IBD is essential.…”

mentioning

confidence: 74%

“…Treatment with topical or systemic corticosteroids for PD-PSV has been benIntroduction Pyodermatitis-pyostomatitis vegetans (PD-PSV) is a rare pustular and vegetating dermatosis frequently associated with inflammatory bowel diseases (IBD) [1] , among which ulcerative colitis (UC) is the most common disease and generally precedes the onset of PD-PSV. The first course of action when treating PD-PSV should be to control the IBD [2,3] . Additionally, various topical or systemic treatments for PD-PSV have been reported.…”

Section: Discussionmentioning

confidence: 99%

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Pyodermatitis-Pyostomatitis Vegetans Associated with Ulcerative Colitis: Successful Treatment with Total Colectomy and Topical Tacrolimus

et al. 2008

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confidence: 74%

Section: Discussionmentioning

confidence: 99%

Pyodermatitis-Pyostomatitis Vegetans Associated with Ulcerative Colitis: Successful Treatment with Total Colectomy and Topical Tacrolimus

et al. 2008

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“…Oral manifestations can also be caused by IBD‐induced malabsorption. Common oral signs and symptoms in patients with CD include pyostomatis vegetans, gingival hyperplasia, papillomatosis of the oral mucosa, vesicular eruptions such as in pemphigus vegetans, periodontitis, and caries (Sundh & Emilson 1989, Mergulhao et al 2005, Ruiz‐Roca et al 2005, Brito et al 2008). Different gingival and mucosal lesions have been reported in association with IBD including hypertrophy and swelling of lips, gingival hyperplasia, resembling epulis fissuratum, cobblestone appearance of the oral mucosa and palate, presence of vesicles, erosions, ulcers, aphthous‐like ulcerations, polypoid “taglike” lesions, and areas of necrosis (“snail‐track” lesions) (Ojha 2007).…”

Section: Extra‐intestinal Manifestations Of Ibdmentioning

confidence: 99%

What can we learn about biofilm/host interactions from the study of inflammatory bowel disease

Indriolo

Greco

Ravelli

et al. 2011

J Clinic Periodontology

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Objectives: The aim of this review was to evaluate possible common pathogenic pathways and risk factors in inflammatory bowel disease (IBD) and periodontitis. Materials and Methods: A MEDLINE-PubMed research was conducted. Results: The pathogenesis of both diseases is multi-factorial leading to a substantial defect of the mucosal barrier, deregulation of the immune response and chronic inflammation of the mucosa. Environmental factors, particularly bacteria, are key factors in the pathogenesis of both diseases. Genetic predisposition is a key factor in the IBD pathogenesis, while a clear role of genetics in the pathogenesis of periodontitis is still unclear. The immune response in IBD is mediated by T lymphocytes as a consequence of a genetic trait associated with T-cell deregulation. On the other hand, in periodontitis plasma cells and lymphocytes are the predominant cells in the chronic inflammatory lesion, with the presence of B cells being proportionally larger than T cells. Conclusion: IBD and periodontitis share several factors in their aetiology and pathogenesis, although they also have distinct characteristics.

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“…There is not a single treatment protocol, and none of the treatment regimens presented solid scientific evidence of having superior efficacy. 2,3,8,9 …”

Section: Discussionmentioning

confidence: 99%

Case for diagnosis

Mesquita

Costa

2012

An. Bras. Dermatol.

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Pyodermatitis-pyostomatitis vegetans is a rare mucocutaneous dermatosis characterized by pustular and vegetating lesions of the skin and oral mucosa. It is considered a highly specific marker for inflammatory bowel diseases. The authors describe a case of pyodermatitis-pyostomatitis vegetans in a pediatric patient who presented marked clinical improvement after beginning treatment with oral corticosteroids, azathioprine, and dapsone. Bowel surveillance is mandatory, since the dermatosis is associated with inflammatory bowel diseases in more than 70% of patients, especially ulcerative colitis.

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Pyostomatitis vegetans. Report of two cases and review of the literature

Cited by 54 publications

References 14 publications

Pyodermatitis-Pyostomatitis Vegetans Associated with Ulcerative Colitis: Successful Treatment with Total Colectomy and Topical Tacrolimus

Pyodermatitis-Pyostomatitis Vegetans Associated with Ulcerative Colitis: Successful Treatment with Total Colectomy and Topical Tacrolimus

What can we learn about biofilm/host interactions from the study of inflammatory bowel disease

Case for diagnosis

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