Pyodermatitis–Pyostomatitis Vegetans of the Eyelids

Leibovitch, Igal; Ooi, Colin; Huilgol, Shyamala C.; Reid, Cathy; James, Craig; Selva, Dinesh

doi:10.1016/j.ophtha.2005.04.027

Cited by 25 publications

(5 citation statements)

References 21 publications

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“…reported a case report of pyodermatitis–pyostomatitis vegetans of the eyelid that completely healed with systemic steroids and sulfasalazine. [ 8 ] In our patient, lesions were located on shoulders, sternum, lower extremity and appeared 3 months after the total colectomy operation.…”

Section: Discussionmentioning

confidence: 71%

Pyodermatitis vegetans after total colectomy

Uzunçakmak

Akdeniz

Karadağ

et al. 2015

Indian Dermatol Online J

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Pyostomatitis–pyodermatitis vegetans (PPV) is a rare dermatological manifestation of inflammatory bowel disease, characterized by erythematous, vesiculopustular, exudative, annular, and/or vegetating plaques over the intertriginous regions that may precede or appear at the same time as the mucosal lesions. Systemic corticosteroids, dapsone, sulfasalazine, azathioprine, cyclosporine, and subtotal/total colectomy are the most common treatment options. A 16-year-old male patient presented to our outpatient clinic with a four months history of thickly crusted erosions on his trunk, back, and lower extremity. He had ulcerative colitis for four years and total colectomy was done seven months ago. Clinical and histopathological examination of his lesions were consistent with pyostomatitis vegetans. Although subtotal/total colectomy has been reported as a treatment option for PPV, lesions reappeared three months after total colectomy in our patient.

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Section: Discussionmentioning

confidence: 71%

Pyodermatitis vegetans after total colectomy

Uzunçakmak

Akdeniz

Karadağ

et al. 2015

Indian Dermatol Online J

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“…1,4,5 It is associated with gastrointestinal disease and has been described as a highly specific marker for inflammatory bowel diseases (IBD). 6,7 Diagnostic differentiation between PD-PSV and pemphigus vegetans is essential, even though immunosuppressant regimen would be similar. The association of PD-PSV with IBD is well known, and IBD precedes the onset of oral lesions by months or years in most cases.…”

Section: Discussionmentioning

confidence: 99%

Case for diagnosis

Mesquita

Costa

2012

An. Bras. Dermatol.

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Pyodermatitis-pyostomatitis vegetans is a rare mucocutaneous dermatosis characterized by pustular and vegetating lesions of the skin and oral mucosa. It is considered a highly specific marker for inflammatory bowel diseases. The authors describe a case of pyodermatitis-pyostomatitis vegetans in a pediatric patient who presented marked clinical improvement after beginning treatment with oral corticosteroids, azathioprine, and dapsone. Bowel surveillance is mandatory, since the dermatosis is associated with inflammatory bowel diseases in more than 70% of patients, especially ulcerative colitis.

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“…The response to systemic steroids is usually very good [11, 13]. Many other treatment modalities, including dapsone, azathioprine, cyclosporine and laser debridement, have been reported only anecdotally in case reports and are generally accepted as second-line therapies [1, 2, 10, 13]. Besides these therapies, topical tacrolimus complementing total colectomy has also been reported to be beneficial in cleaning lesions [10].…”

Section: Discussionmentioning

confidence: 99%

Pyoderma Vegetans Associated with Ulcerative Colitis: A Case with Good Response to Steroids

Canpolat¹,

Cemil²,

Yılmazer

et al. 2011

Case Rep Dermatol

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Pyoderma vegetans (PV) is a very rare disorder characterized by erythematous, vesiculopustular, exudative, vegetating plaques usually localized in the inguinal and axillary folds. The etiology of PV is not known, but it is often associated with bacterial infections in immunocompromised patients. Major histopathological features in PV are pseudoepitheliomatous hyperplasia and intraepidermal and subepidermal neutrophilic or eosinophilic microabscesses. It is well known that these lesions are frequently associated with inflammatory bowel diseases, such as ulcerative colitis (UC) and Crohn’s disease. No standardized treatment plan is available for PV, although antibiotic treatment has often been used, with variable results. The standard first-line therapy is still systemic steroids. Herein, we report a case of PV associated with UC with unusual localization that showed a good response to systemic corticosteroid, antibiotic and sulfasalazine therapy.

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Pyodermatitis–Pyostomatitis Vegetans of the Eyelids

Cited by 25 publications

References 21 publications

Pyodermatitis vegetans after total colectomy

Pyodermatitis vegetans after total colectomy

Case for diagnosis

Pyoderma Vegetans Associated with Ulcerative Colitis: A Case with Good Response to Steroids

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