Pyoderma vegetans: Association with diffuse T cell lymphoma (large cell type)

Welch, Keasley; Burke, William A.; Park, H. Kim

doi:10.1016/s0190-9622(89)80154-9

Cited by 20 publications

(10 citation statements)

References 12 publications

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“…Cases have been reported on a background of HIV-AIDS;[2–4] inflammatory bowel disease;[5] lupus nephritis;[6] and mycosis fungoides. [7] Treatment options for PV are curettage, antibiotics, and topical therapies including aluminium subacetate soaks and attention to any underlying systemic illness. In summary, we describe a 41-year-old male with known IgA deficiency in whom PV responded successfully to topical treatment.…”

Section: Discussionmentioning

confidence: 99%

Pyoderma vegetans with Ig A deficiency

et al. 2010

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Section: Discussionmentioning

confidence: 99%

Pyoderma vegetans with Ig A deficiency

et al. 2010

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“…HIV infection [10], malignant tumors, i.e. lymphomas [11], leukemia [12], carcinomas [13], alcoholism, nutritional deficit, diabetes mellitus [14], or therapy with immunosuppressive agents [4], and even in other situations such as bowel inflammatory disease [15, 16], and acne conglobata and follicular occlusion triad [17]. Treatment of this condition is usually very difficult.…”

Section: Discussionmentioning

confidence: 99%

Pyoderma Vegetans Associated with Severe Psoriatic Arthritis: Good Response to Etanercept

Carrera

Mascaró²,

Moreno-Romero³

et al. 2006

Dermatology

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Pyoderma vegetans (PV) is an inflammatory dermatosis, characterized clinically by large exudative vegetating plaques, and histopathologically by epidermal pseudoepitheliomatous hyperplasia and dense inflammatory infiltrates. Although PV is a very rare condition, it is a chronic disorder that may accompany any systemic process that compromises immunity. Treatment is very difficult, and correction of predisposing causes may be useful. We present a 49-year-old woman affected by severe psoriatic arthritis since she was 19, with giant verrucous plaques on her lower limbs that had worsened progressively during the last 15 years. After ruling out other vegetating cutaneous disorders, PV was diagnosed in association with psoriasis. Despite numerous previous systemic and topical therapeutic attempts no response was observed. Etanercept was introduced, which resulted in a marked improvement within 3 weeks. Herein, we report a diagnostic and therapeutic challenge of the first case of PV associated with psoriasis that presented a good response to etanercept.

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“…1 This theory has been supported by recent reports. 2,6,9 Pyoderma vegetans has been associated with ulcerative colitis, 5 diffuse T-cell lymphoma, 6 alcoholism with malnutrition, 1 HIV infection, 7 and chronic myeloid leukemia. 10 Su et al 2 reported seven patients with clinically characteristic pyoderma vegetans.…”

Section: Discussionmentioning

confidence: 99%

“…[1][2][3][4] This vegetating reaction is believed to be due to an immune system dysfunction or immunosuppressive state. Ulcerative colitis, 5 diffuse T-cell lymphoma, 6 and HIV infection 7 have all been linked to this condition.…”

Section: Sommairementioning

confidence: 99%