Pyoderma gangrenosum and Chlamydia pneumoniae infection in a diabetic man: Pathogenic role or coincidence?

Antimicrobial Treatment of Multiple Sclerosis

“…This is a survival mechanism involving a phenotypic simplification of the metabolic economy under the onset of stress conditions. Survival in this form may depend upon a nonoxidative metabolic pathway [9]. The finding that Chlamydiae enter the cryptic form when starved of amino acids [10] lends support to the idea of persistence being a stringent response.…”

Chlamydia pneumoniae and Chronic Skin Wounds: A Focused Review

“…Abrams et al (1999) claimed that 12 of 27 patients with cutaneous T cell lymphoma had a C. pneumoniae-associated protein that activated Sezary T cells. Vannucci et al (2000) detected C. pneumoniae serologically in a diabetic patient with pyoderma gangrenosum-like lesions that responded dramatically to antibiotics directed against Chlamydia. Sams et al (2001) identi®ed by serologic, immunohistochemical, and culture methods C. pneumoniae in a patient with pyoderma gangrenosum that responded to prolonged antichlamydial antibiotic therapy with decreases in anti-C. pneumoniae antibody titers.…”