Pycnanthuquinone C: A New Terpenoid-Quinone from <i>Pycnanthus angolensis</i>

Wabo, Hippolyte K.; Tatsimo, Simplice N; Tané, Pierre; Connolly, Joseph D.

doi:10.1055/s-2007-967103

Cited by 24 publications

(19 citation statements)

References 9 publications

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“…[83], Wabo et al . [98] and Tamokou et al . [99] on Senecio mannii , Ceiba pentandra , Diospyros canaliculata , Psorospermum febrifugum , Pycnanthus angolensis and Coula edulis respectively.…”

Section: Resultsmentioning

confidence: 99%

Cameroonian medicinal plants: a bioactivity versus ethnobotanical survey and chemotaxonomic classification

Ntie‐Kang

Lifongo

Mbaze

et al. 2013

BMC Complement Altern Med

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BackgroundIn Cameroon herbs are traditionally used to meet health care needs and plans are on the way to integrate traditional medicine in the health care system, even though the plans have not been put into action yet. The country however has a rich biodiversity, with ~8,620 plant species, some of which are commonly used in the treatment of several microbial infections and a range of diseases (malaria, trypanosomiasis, leishmaniasis, diabetes and tuberculosis).MethodsOur survey consisted in collecting published data from the literature sources, mainly from PhD theses in Cameroonian university libraries and also using the author queries in major natural product and medicinal chemistry journals. The collected data includes plant sources, uses of plant material in traditional medicine, plant families, region of collection of plant material, isolated metabolites and type (e.g. flavonoid, terpenoid, etc.), measured biological activities of isolated compounds, and any comments on significance of isolated metabolites on the chemotaxonomic classification of the plant species. This data was compiled on a excel sheet and analysed.ResultsIn this study, a literature survey led to the collection of data on 2,700 secondary metabolites, which have been previously isolated or derived from Cameroonian medicinal plants. This represents distinct phytochemicals derived from 312 plant species belonging to 67 plant families. The plant species are investigated in terms of chemical composition with respect to the various plant families. A correlation between the known biological activities of isolated compounds and the ethnobotanical uses of the plants is also attempted. Insight into future direction for natural product search within the Cameroonian forest and Savanna is provided.ConclusionsIt can be verified that a phytochemical search of active secondary metabolites, which is inspired by knowledge from the ethnobotanical uses of medicinal plants could be very vital in a drug discovery program from plant-derived bioactive compounds.

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Section: Resultsmentioning

confidence: 99%

Cameroonian medicinal plants: a bioactivity versus ethnobotanical survey and chemotaxonomic classification

Ntie‐Kang

Lifongo

Mbaze

et al. 2013

BMC Complement Altern Med

View full text Add to dashboard Cite

show abstract

“…and Thonn) Taub. (12117/SRFCam) Tonic, purgative, emetic, convulsions, leprosy, anti-inflammatroy, rheumatic pains (Dalziel, 1948;Ojewole and Adesina, 1983;Oliver-Bever, 1983 (Keay et al, 1964;Lok et al, 1983;Omobuwajo et al, 1992;Akendengué and Louis, 1994;Fort et al, 2000;Wabo et al, 2007;Abrantes et al, 2008) Bark leaves, root, wood Leaves (19.76) Antihelmintic and anticancer: dihydroguaiaretic acid (Abrantes et al, 2008), Antihyperglycemic: pycnanthuquinones A and B (Luo et al, 1999;Fort et al, 2000;Gbolade and Adeyemi, 2008), Antimicrobial: pycnanthulignene A pycnanthulignene C 3,4-dimethoxy-3 ,4 -methylenedioxy-7,7 -epoxylignan; genkwainin; pycnanthulignene C; 4,5-dimethoxy-3 ,4 -methylenedioxy-2,7 -cycloligna-7,7 -diene; pycnanthulignene A; calycosin; biochanin A; prunetin …”

Section: Whole Plantmentioning

confidence: 99%