Pustulose exanthématique aiguë généralisée succédant à une morsure d’araignée : trois observations tunisiennes

Said, Z. Ben; Saïdi, W.; Boussofara, L.; Ghariani, N.; Belajouza, C.; Sriha, Badreddine; Denguezli, M.; Nouira, R.

doi:10.1016/j.annder.2010.06.015

Cited by 20 publications

(3 citation statements)

References 9 publications

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“…Earlier also, cases of AGEP secondary to insect bites have been reported from India[ 3 ] and also from other parts of the world. [ 28 29 30 31 32 33 ] The exact mechanism behind the development of AGEP following spider bite is unknown, but it is postulated that the spider venom contains sphingomyelinase, which can lead to the release of various inflammatory mediators that trigger AGEP. [ 33 34 ]…”

Section: Discussionmentioning

confidence: 99%

Etiopathological and clinical study of acute generalized exanthematous pustulosis: Experience from a tertiary care hospital in North India

Bhat

Akhtar

Ahmad

et al. 2020

Indian Dermatol Online J

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Section: Discussionmentioning

confidence: 99%

Etiopathological and clinical study of acute generalized exanthematous pustulosis: Experience from a tertiary care hospital in North India

Bhat

Akhtar

Ahmad

et al. 2020

Indian Dermatol Online J

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“…The latter is a serious skin reaction, often resulting from drug intake. However, other causes, such as infections, food allergies, 35 mercury exposure, 36 and spider bites 37 are increasingly reported 16…”

Section: Etiologymentioning

confidence: 99%

Acute localized exanthematous pustulosis: Clinical features, pathophysiology, and therapy

Idoudi

Lahouel

Litaiem³

et al. 2021

Dermatologic Therapy

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Acute localized exanthematous pustulosis (ALEP) is a rare disease characterized by the acute onset of multiple localized non‐follicular, pinhead‐sized pustules. ALEP is considered a localized form of acute generalized exanthematous pustulosis but its pathogeny is not well identified. We performed a systematic review of the literature of all publications regarding ALEP cases using the term “acute localized exanthematous pustulosis,” to provide an update on this disease and its management. Results and conclusion ALEP is an uncommon skin condition attributed primarily to a hypersensitivity reaction to a systemic drug (classical or herbal); though a contact mechanism has been reported. It may be misdiagnosed as infectious or inflammatory disease but the clinico‐pathological correlation in addition to the rapid response to withdrawal of the culprit agent supports this diagnosis. The pathogenesis of ALEP is still unclear, and there are no standardized treatment guidelines to manage this disease. Both AGEP and ALEP have a good prognosis if an early diagnosis is made.

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“…Because there was no history of drug use in their case, they attributed her AGEP lesions to the spider bite. [ 10 ] Makris et al reported (AGEP) triggered by a spider bite in 2009;[ 11 ] Pippirs et al reported AGEP following a Loxosceles spider bite in Great Britain in 2009;[ 12 ] and Lane et al reported AGEP and Coombs-positive hemolytic anemia in a child following Loxosceles reclusa envenomation in 2011. [ 13 ]…”

Section: Discusssionmentioning

confidence: 99%

Acute generalized exanthematous pustulosis due to insect bites?

et al. 2015

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Acute generalized exanthematous pustulosis is a rare severe cutaneous adverse reaction pattern that is mostly caused by the intake of drugs and rarely associated with viral infections, food allergens or toxins. Here we present the report of three patients who got admitted in our hospital for generalized pustulosis and fever after insect bites. The diagnosis of acute generalized exanthematous pustulosis was made by EuroSCAR scoring. The drug etiology was excluded and spider bite was implicated as the etiological agent in these cases of AGEP which are the first such reported cases in India.

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Pustulose exanthématique aiguë généralisée succédant à une morsure d’araignée : trois observations tunisiennes

Cited by 20 publications

References 9 publications

Etiopathological and clinical study of acute generalized exanthematous pustulosis: Experience from a tertiary care hospital in North India

Etiopathological and clinical study of acute generalized exanthematous pustulosis: Experience from a tertiary care hospital in North India

Acute localized exanthematous pustulosis: Clinical features, pathophysiology, and therapy

Acute generalized exanthematous pustulosis due to insect bites?

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