Purtscher's retinopathy and fat embolism.

Roden, Dermot; Fitzpatrick, G.; O’Donoghue, H. N.; Phelan, Dermot

doi:10.1136/bjo.73.8.677

Cited by 47 publications

(21 citation statements)

References 4 publications

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“…15,22 The fat embolism syndrome (fever, respiratory distress, central nervous system changes and a petechial rash) occurs in approximately 5% of patients with long bone fractures and affects multiple organ systems. It may be fatal in 20% of severe cases.…”

Section: Fatmentioning

confidence: 99%

Purtscher’s retinopathy

Buckley

James

1996

Postgraduate Medical Journal

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Summary Purtscher’s retinopathy presents to the clinician as loss of vision in a patient with a history of a possible precipitating event such as recent major trauma, pancreatitis, childbirth or renal failure. The ophthalmological picture is one of ischaemia at the posterior pole with white patches of oedema and haemorrhages concentrated around the optic disc. The most probable pathological cause is embolisation of the peripapillary terminal arterioles supplying the superficial peripapillary capillary net. The nature of the embolic particles remains uncertain. Complement-mediated aggregates, fat, air, fibrin clots and platelet clumps may all be involved in what is most likely to be a multifactorial process. There is at present no recognised treatment for the condition.

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Section: Fatmentioning

confidence: 99%

Purtscher’s retinopathy

Buckley

James

1996

Postgraduate Medical Journal

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“…Fat emboli are known to occur both in trauma and pancreatis2" and fat emboli have been postulated as the cause of Purtscher's retinopathy in these situations. 15,22 The fat embolism syndrome (fever, respiratory distress, central nervous system changes and a petechial rash) occurs in approximately 5% of patients with long bone fractures and affects multiple organ systems. It may be fatal in 20% of severe cases.…”

Section: Fatmentioning

confidence: 99%

Purtscher’s Retinopathy

Forlini¹,

Forlini²

2017

Ophthalmology: Current and Future Developments

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Purtscher's retinopathy presents to the clinician as loss of vision in a patient with a history of a possible precipitating event such as recent major trauma, pancreatitis, childbirth or renal failure. The ophthalmological picture is one of ischaemia at the posterior pole with white patches of oedema and haemorrhages concentrated around the optic disc. The most probable pathological cause is embolisation of the peripapillary terminal arterioles supplying the superficial peripapillary capillary net. The nature of the embolic particles remains uncertain. Complement-mediated aggregates, fat, air, fibrin clots and platelet clumps may all be involved in what is most likely to be a multifactorial process. There is at present no recognised treatment for the condition.

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“…The pathogenic concept includes capillary occlusions due to complement-activated leukocytes or fat embolism [3,4], The visual outcome is extremely variable and dependent on the extent of optic nerve head and retinal involvement. Para central scotomata are common sequelae [5].…”

Section: Com M Entmentioning

confidence: 99%

Morphologic Changes of the Macula in a Patient with Purtscher’s Retinopathy

et al. 1997

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Purtscher’s retinopathy is a rare complication after trauma to the chest or bone fractures. We report about a patient, which we examined 6 months after a serious car accident. Visual acuity was 20/20 in both eyes. Examination with the Amsler grid revealed a paracentral scotoma in the left eye. In the fluorescein angiography of the left eye performed with a scanning laser ophthalmoscope we found capillary dropout, which corresponded well to the scotoma. Measured by digital image analysis, the area of the foveal avascular zone was eccentrically enlarged by a factor of 4. The mean perifoveal intercapillary area was also enlarged in the corresponding quadrant. This reflects that focal capillary dropout may result in scotoma rather than in a decrease in visual acuity as reported in other diseases.

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Purtscher's retinopathy and fat embolism.

Cited by 47 publications

References 4 publications

Purtscher’s retinopathy

Purtscher’s retinopathy

Purtscher’s Retinopathy

Morphologic Changes of the Macula in a Patient with Purtscher’s Retinopathy

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