Purpura Fulminans in a Child: A Case Report

Aroor, Shrikiran; Varma, Chaitanya; Mundkur, Suneel C

doi:10.7860/jcdr/2012/4339.2618

Cited by 6 publications

(5 citation statements)

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“…We performed a Medline search to identify any related articles using the key words "purpura fulminans" and "P. aeruginosa". As a result, we found two reports: one by Lerolle et al and one by Aroor et al [7,8] Lerolle et al reported the results of fluorescence confocal microscopy, which showed P. aeruginosa in the dermal vessels of a deceased patient with purpura fulminans. [7] Microorganisms were typically identified inside the capillaries in foci with multiple bacteria in the purpuric skin.…”

Section: Discussionmentioning

confidence: 76%

“…reported an eight-year-old boy who presented with a fever and purpuric rash involving all four limbs. [8] Their patient eventually developed gangrene of all digits and the pinna, and the condition deteriorated progressively until he was discharged against medical advice in a moribund state. In that case, the blood culture grew P., but whether or not it was P. aeruginosa was unknown.…”

Section: Discussionmentioning

confidence: 99%

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Acute Infectious Purpura Fulminans Complicated with Multiple Erosions

Ikegami¹,

Jitsuiki²,

Muramatsu³

et al. 2020

AJMCR

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An 80-year-old man was extremely skinny and developed a left leg phlegmon. He was admitted and underwent an infusion of cefazolin. On the third day, he suddenly collapsed, and advanced cardiac life support resulted in a return of his circulation. He showed vasopressor-resistant hypotension and therefore received an infusion of steroids and multiple supportive therapies. A blood culture later showed Pseudomonas aeruginosa. While his blood pressure increased, he showed peripheral and labile cyanotic changes, even though his peripheral arteries were palpable. On the third day after the collapse, he showed blisters at purpura sites and labile, resulting in the formation of erosions. On the fourth day, massive effusion was drained from the erosive lesions. He temporarily showed a return of consciousness, but his extremities became necrotic, and he ultimately died due to a secondary infection at the erosive lesions. The present fatal case of acute infectious purpura fulminans might have been induced by a P. aeruginosa infection due to complications with multiple blisters, similar to Stevens-Johnson syndrome/toxic epidermal necrolysis. Early aggressive surgical amputation or debridement might be required to obtain a survival outcome when encountering such cases.

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Section: Discussionmentioning

confidence: 76%

Section: Discussionmentioning

confidence: 99%

Acute Infectious Purpura Fulminans Complicated with Multiple Erosions

Ikegami¹,

Jitsuiki²,

Muramatsu³

et al. 2020

AJMCR

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“…However, it is convenient to think about other etiological possibilities. 6 The characteristic lesions of purpura fulminans are erythematous lesions greater than 2 mm until their color turn purplish on the center, which does not disappear upon acupressure. They are indurated, painful with palpation and secondary to capillary extravasation, progressing to necrosis and with the presence of thrombosis in the microcirculation.…”

Section: Discussionmentioning

confidence: 99%

Community-acquired pneumonia with infrequent presentation

Pérezpeña-Díazconti¹,

Moreno-Espinosa²,

Romero-Baizabal³

et al. 2023

BMHIME

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“…PF is a rare, life-threatening disorder of acute onset skin lesions due to disseminated intravascular coagulopathy (DIC) and small vessel thrombosis of the dermis, which is characterized by hemorrhagic infarction of skin (8). DIC triggers systemic activation of blood coagulation resulting in excessive blood clotting, which leads to endothelial injury.…”

Section: Discussionmentioning

confidence: 99%

Association of COVID-19 Infection and Purpura Fulminans

Dashti¹,

Dehghani

Moravej

et al. 2021

Arch Pediatr Infect Dis

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: Coronavirus disease 2019 (COVID-19) was officially declared as a pandemic on March 11, 2020. Although most patients with COVID-19 manifest fever and respiratory tract symptoms, extrapulmonary and atypical presentations, such as gastrointestinal, neurologic, and cardiovascular involvement as well as thromboembolic events have been reported amongst COVID-19 patients. Herein, we aim to describe a COVID-19 patient who progressed to purpura fulminans.

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Purpura Fulminans in a Child: A Case Report

Abstract: Purpura Fulminans is a life threatening condition characterised by cutaneous haemorrhage and gangrenous necrosis. We present such a case in an eight year old child.

Cited by 6 publications

References 0 publications

Acute Infectious Purpura Fulminans Complicated with Multiple Erosions

Acute Infectious Purpura Fulminans Complicated with Multiple Erosions

Community-acquired pneumonia with infrequent presentation

Association of COVID-19 Infection and Purpura Fulminans

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