Purinoceptors in blood feeding behaviour in the stable fly, Stomoxys calcitrans

Abstract

Both sexes of the stable fly, Stomoxys calcitrans L. (Diptera: Muscidae), have receptors on their mouthparts that mediate blood feeding. The potency ranking of the adenine nucleotides (ATP > ADP > AMP > adenosine) in eliciting feeding and suppressing the NaCl‐sensitive cell may indicate the involvement of a P2‐type receptor. This is supported by the lack of effect on feeding by methyl xanthines. Feeding‐related behavioural and electrophysiological results demonstrate that the potency of CH3‐S‐ATP is not greater than that of ATP. These ATP‐mediated responses are antagonized by ANAPP3. Results support the conclusion that the putative ‘ATP receptor’ involved in stable fly phagostimulation resembles the P2x purinoceptor of vertebrates.

Oviposition stimulants for the pipevine swallowtail butterfly,Battus philenor (Papilionidae), from anAristolochia host plant: Synergism between inositols, aristolochic acids and a monogalactosyl diglyceride

“…Though the resemblance of exteroreceptive purinoceptors in invertebrates to the enteroreceptive purinoceptors of vertebrates could have resulted from convergent evolution, it may instead result from an ancient common origin, perhaps dating back to the use of exogenous ATP detection by the earliest heterotrophs (Ascoli-Christensen et al 1991). Comparable analogies between neurotransmitter functions in vertebrates and chemoreceptive roles in invertebrates may indicate a similarly ancient origin for receptors responding to inositols and diacyl glycerides.…”